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Wnt Agonist

CAS No.
853220-52-7
Chemical Name:
Wnt Agonist
Synonyms
BML;-284;AMBMP;BML-284;CS-2376;Wnt Agonist;2-Amino-4-[3;Wnt agonist 1;Wnt Agonist I;BML-284 (BML 284
CBNumber:
CB42750501
Molecular Formula:
C19H18N4O3
Molecular Weight:
350.37
MDL Number:
MFCD09908087
MOL File:
853220-52-7.mol
MSDS File:
SDS
Last updated:2023-05-18 11:31:20

Wnt Agonist Properties

Boiling point 623.4±65.0 °C(Predicted)
Density 1.353±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: soluble20mg/mL, clear
pka 6.62±0.10(Predicted)
form Yellowish sticky solid
color white to beige

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/38
Safety Statements  26-39
WGK Germany  3

Wnt Agonist price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML0698 CID 11210285 hydrochloride ≥98% (HPLC) 853220-52-7 5mg $119 2024-03-01 Buy
Sigma-Aldrich SML0698 CID 11210285 hydrochloride ≥98% (HPLC) 853220-52-7 25mg $386 2024-03-01 Buy
Sigma-Aldrich 681665 Wnt Agonist - CAS 853220-52-7 - Calbiochem The Wnt Agonist, also referenced under CAS 853220-52-7, controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for Cancer applications. 853220-52-7 5mg $265 2024-03-01 Buy
Cayman Chemical 19903 Wnt Agonist I ≥98% 853220-52-7 5mg $93 2024-03-01 Buy
Cayman Chemical 19903 Wnt Agonist I ≥98% 853220-52-7 10mg $120 2024-03-01 Buy
Product number Packaging Price Buy
SML0698 5mg $119 Buy
SML0698 25mg $386 Buy
681665 5mg $265 Buy
19903 5mg $93 Buy
19903 10mg $120 Buy

Wnt Agonist Chemical Properties,Uses,Production

Uses

CID 11210285 hydrochloride has been used as a Wnt agonist.

Definition

ChEBI: N4-(1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)pyrimidine-2,4-diamine is a member of pyrimidines.

Biological Activity

wnt agonist 1 is a small-molecule agonist of wnt signaling pathway [1].the wnt signaling pathway is an important signal transduction pathway that involved in a variety of physiological and pathological processes by regulating genes involved in cellular adhesion, proliferation, and differentiation [1].wnt agonist 1 is a cell-permeable wnt signaling pathway agonist. wnt agonist 1 induced b-catenin- and tcf-dependent transcriptional activity in a dose-dependent way with ec50 of 0.7 μm. in xenopus embryos, treatment with wnt agonist 1 (10 μm) from developmental stage 10.5 to stage 40 resulted in substantial head defects, such as diminished heads and complete loss of eyes, and reduced eyes and heads. this phenotype is similar to that which results from wnt over-expression in head specification during early embryonic development.

Biochem/physiol Actions

CID 11210285 is a cell-permeable, potent and selective activator of Wnt signaling without inhibiting GSK-3β. CID 11210285is a Wnt agonist.

References

liu j, wu x, mitchell b, et al. a small-molecule agonist of the wnt signaling pathway. angew chem int ed engl. 2005 mar 18;44(13):1987-90.

Wnt Agonist Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 78)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32686 60
Biochempartner
0086-13720134139 candy@biochempartner.com CHINA 967 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd
+86-86-22-87899925 +86-8618522618860 18522618860@163.com China 694 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10523 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
LEAP CHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 24738 58
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58
ShenZhen Trendseen Biological Technology Co.,Ltd.
13417589054 trendseenbio@gmail.com China 11681 58

View Lastest Price from Wnt Agonist manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Wnt Agonist pictures 2019-12-24 Wnt Agonist
853220-52-7
US $1.00 / g 1g 99% 20kg Career Henan Chemical Co
  • Wnt Agonist pictures
  • Wnt Agonist
    853220-52-7
  • US $1.00 / g
  • 99%
  • Career Henan Chemical Co

Wnt Agonist Spectrum

AMBMP CID 11210285 hydrochloride N4-(1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)-2,4-pyrimidinediamine hydrochloride Wnt agonist 1 BML-284 2-Amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine hydrochloride Wnt agonist 1 (BML-284) N4-(1,3-Benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)-2,4-pyrimidinediamine Wnt Agonist Wnt Agonist I BML-284 (BML 284 CS-2376 Wnt Agonist - CAS 853220-52-7 - Calbiochem Wnt Agonist I in DMSO - CAS 853220-52-7 - Calbiochem BML-284 (Wnt agonist 1) Wnt agonist 1 hydrochloride 2-Amino-4-[3 4-(methylenedioxy)benzylamino]-6-(3-methoxyphenyl)pyrimidine BML-284;2-AMINO-4-[3;4-(METHYLENEDIOXY)BENZYLAMINO]-6-(3-METHOXYPHENYL)PYRIMIDINE CID 11210285 HCL(BML-284 HCl) -284 BML 2,4-Pyrimidinediamine, N4-(1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)- BML-284 HCl,Wnt Agonist N-cadherin,E-cadherin,malformed phenotype,BML 284,Wnt,inhibit,AGS,BML284,BML-284,TCF,Inhibitor,cardiac defect,MNK45 853220-52-7