Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>OLOMOUCINE II

OLOMOUCINE II

OLOMOUCINE II Structure
OLOMOUCINE II structure
CAS No.
500735-47-7
Chemical Name:
OLOMOUCINE II
Synonyms
Nsc736738;Olomoucine II - CAS 500735-47-7 - Calbiochem;Olomoucine ii, 6-[(2-hydroxybenzyl)amino]-2-[1-(hydroxymethyl)propylamino]- 9-isopropylpurine;2-[[[2-[[(1R)-1-(Hydroxymethyl)propyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]methyl]phenol;Phenol, 2-[[[2-[[(1R)-1-(hydroxymethyl)propyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]methyl]-
CBNumber:
CB4504061
Molecular Formula:
C19H26N6O2
Molecular Weight:
370.45
MDL Number:
MFCD06411574
MOL File:
500735-47-7.mol
Last updated:2023-07-14 17:34:45
Request For Quotation

OLOMOUCINE II Properties

Boiling point 618.5±65.0 °C(Predicted)
Density 1.32
storage temp. −20°C
solubility chloroform: 50 mg/mL, soluble
form powder
pka 9.83±0.30(Predicted)

SAFETY

Risk and Safety Statements

Safety Statements  22-24/25
WGK Germany  3

OLOMOUCINE II price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 495621 Olomoucine II 500735-47-7 5mg $308 2023-01-07 Buy
American Custom Chemicals Corporation API0008354 OLOMOUCINE II 95.00% 500735-47-7 1MG $144.9 2021-12-16 Buy
Product number Packaging Price Buy
495621 5mg $308 Buy
API0008354 1MG $144.9 Buy

OLOMOUCINE II Chemical Properties,Uses,Production

Definition

ChEBI: 2-[[[2-(1-hydroxybutan-2-ylamino)-9-propan-2-yl-6-purinyl]amino]methyl]phenol is a thiopurine.

General Description

A cell-permeable 2,6,9-trisubstituted purine analog that acts as a potent, reversible, and ATP-competitive inhibitor of Cdk1/B with an IC50 of 20 nM and displays increased potency over purvalanol A (Cat. No. 540500; IC50 = 50 nM), Roscovitine (Cat. No. 557360; IC50 = 450 nM), Bohemine (Cat. No. 203600; IC50 = 1.1 μM) and Olomoucine (Cat. No. 495620; IC50 = 7.0 μM). Further, exerts greater in vitro cytotoxicity in various cancer cell lines (IC50 = 3.0 μM, 5.3 μM, 6.3 μM, 6.3 μM and 11.1 μM for CEM, MCF7, HOS, G631 and K562, respectively).

Biochem/physiol Actions

Cell permeable: yes

OLOMOUCINE II Preparation Products And Raw materials

Raw materials

Preparation Products

OLOMOUCINE II Suppliers

Global( 11)Suppliers
Supplier Tel Email Country ProdList Advantage
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 52927 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58
ChemeGen 中国 18818260767 sales@chemegen.com China 6975 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24131 58
Supplier Advantage
Aladdin Scientific 		58
Sigma-Aldrich 80
Shanghai EFE Biological Technology Co., Ltd. 58
ChemeGen 中国 58
TargetMol Chemicals Inc. 58

500735-47-7(OLOMOUCINE II)Related Search:

Ro 3306 N9-ISOPROPYL-OLOMOUCINE (S)-ROSCOVITINE NU6140 3-amino-10H-acridine-9-thione
ARCYRIAFLAVIN A PURVALANOL A 2(BIS-(HYDROXYETHYL)AMINO)-6-(4-METHOXYBENZYLAMINO)-9-ISOPROPYL-PURINE AMINOPURVALANOL A SU 9516
NU6102 OLOMOUCINE

1of3

Nsc736738 Olomoucine ii, 6-[(2-hydroxybenzyl)amino]-2-[1-(hydroxymethyl)propylamino]- 9-isopropylpurine 2-[[[2-[[(1R)-1-(Hydroxymethyl)propyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]methyl]phenol Olomoucine II - CAS 500735-47-7 - Calbiochem Phenol, 2-[[[2-[[(1R)-1-(hydroxymethyl)propyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]methyl]- 500735-47-7