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ChemicalBook >> CAS DataBase List >>1-(4-CHLORO-BENZYL)-1 H-INDOLE-3-CARBALDEHYDE

1-(4-CHLORO-BENZYL)-1 H-INDOLE-3-CARBALDEHYDE

1-(4-CHLORO-BENZYL)-1 H-INDOLE-3-CARBALDEHYDE Structure
1-(4-CHLORO-BENZYL)-1 H-INDOLE-3-CARBALDEHYDE structure
CAS No.
75629-57-1
Chemical Name:
1-(4-CHLORO-BENZYL)-1 H-INDOLE-3-CARBALDEHYDE
Synonyms
CS-1229;Oncrasin 1;ZERO/008607;ZINC00439476;AKOS B014321;Oncrasin 1 >ASISCHEM N15726;ART-CHEM-BB B014321;CHEMBRDG-BB 5601604;1-(4-chlorobenzyl)indole-3-carbaldehyde
CBNumber:
CB4698434
Molecular Formula:
C16H12ClNO
Molecular Weight:
269.73
MDL Number:
MFCD01051808
MOL File:
75629-57-1.mol
Last updated:2023-06-30 15:45:59
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1-(4-CHLORO-BENZYL)-1 H-INDOLE-3-CARBALDEHYDE Properties

Melting point 115.0 to 119.0 °C
Boiling point 465.5±30.0 °C(Predicted)
Density 1.21±0.1 g/cm3(Predicted)
storage temp. Inert atmosphere,2-8°C
solubility DMSO: ≥20mg/mL
form powder
color off-white to light tan
Sensitive Light Sensitive

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Hazard Codes  Xi
WGK Germany  3
HS Code  2933.99.9000
HazardClass  IRRITANT
NFPA 704
0
2 0

1-(4-CHLORO-BENZYL)-1 H-INDOLE-3-CARBALDEHYDE price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 496265 Oncrasin-1 75629-57-1 25mg $128 2023-06-20 Buy
Sigma-Aldrich O0516 Oncrasin-1 ≥98% (HPLC) 75629-57-1 5mg $109 2022-05-15 Buy
TCI Chemical O0450 Oncrasin 1 >95.0%(HPLC) 75629-57-1 10mg $112 2024-03-01 Buy
TCI Chemical O0450 Oncrasin 1 >95.0%(HPLC) 75629-57-1 50mg $390 2024-03-01 Buy
Alfa Aesar J64018 Oncrasin 1 75629-57-1 10mg $128 2021-12-16 Buy
Product number Packaging Price Buy
496265 25mg $128 Buy
O0516 5mg $109 Buy
O0450 10mg $112 Buy
O0450 50mg $390 Buy
J64018 10mg $128 Buy

1-(4-CHLORO-BENZYL)-1 H-INDOLE-3-CARBALDEHYDE Chemical Properties,Uses,Production

Uses

Oncrasin 1 is a proapoptotic compound.

Definition

ChEBI: Oncrasin-1 is a member of the class of indoles that is 1H-indole substituted by 4-chlorobenzyl and formyl groups at positions 1 and 3, respectively. It is an anti-cancer agent that is active against lung cancer cells with K-Ras mutations. It has a role as an apoptosis inducer and an antineoplastic agent. It is a member of indoles, a member of monochlorobenzenes and an arenecarbaldehyde.

Biological Activity

Proapoptotic agent that induces abnormal nuclear aggregation of PKC ι and suppresses RNA transcription. Exhibits antiproliferative effects against various human tumor cell lines with K-Ras mutations (IC 50 ≤ 3 μ M) with minimal effects on normal epithelial cells and inhibits human xenograft growth by 75% in vivo .

storage

+4°C

1-(4-CHLORO-BENZYL)-1 H-INDOLE-3-CARBALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

1-(4-CHLORO-BENZYL)-1 H-INDOLE-3-CARBALDEHYDE Suppliers

Global( 115)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32686 60
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19553 58
Wuhan Chemwish Technology Co., Ltd 		027-67849912 sales@chemwish.com CHINA 10828 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		+8613580539051 joe@yuhengpharm.com CHINA 21149 58
Career Henan Chemica Co 		+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
LEAPCHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 43348 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 57511 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
BOC Sciences 		58
Wuhan Chemwish Technology Co., Ltd 		58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		58
Career Henan Chemica Co 		58
InvivoChem 		58
TargetMol Chemicals Inc. 		58
LEAPCHEM CO., LTD. 		58
Aladdin Scientific 		58
J & K SCIENTIFIC LTD. 76

75629-57-1(1-(4-CHLORO-BENZYL)-1 H-INDOLE-3-CARBALDEHYDE)Related Search:

Indibulin 1-(3,4-DICHLORO-BENZYL)-1H-INDOLE-3-CARBALDEHYDE 1-(4-CHLORO-BENZYL)-1 H-INDOLE-3-CARBALDEHYDE ASISCHEM R41968 1-(2,4-DICHLORO-BENZYL)-1H-INDOLE-3-CARBALDEHYDE
1-(2-CHLORO-BENZYL)-1H-INDOLE-3-CARBALDEHYDE 1-(4-CHLOROBENZYL)-N-PHENYL-1H-INDOLE-3-CARBOXAMIDE METHYL 1-(2,4-DICHLOROBENZOYL)-1H-INDOLE-3-CARBOXYLATE METHYL 1-(4-CHLOROBENZOYL)-1H-INDOLE-3-CARBOXYLATE CBI-BB ZERO/008374
CBI-BB ZERO/005692 1-(4-CHLOROBENZYL)-N-(4-METHOXYPHENYL)-1H-INDOLE-3-CARBOXAMIDE 1H-INDOLE-3-CARBOXYLIC ACID, 1-[(2,4-DICHLOROPHENYL)METHYL]-,METHYL ESTER ASISCHEM V95851 1-(4-CHLOROBENZYL)-1H-INDOLE-3-CARBOXYLIC ACID
1H-INDOLE-3-CARBOXYLIC ACID, 1-[(3,4-DICHLOROPHENYL)METHYL]-, METHYL ESTER 5-BROMO-1-(4-CHLOROBENZYL)-1H-INDOLE-3-CARBALDEHYDE N-BENZYL-1-(4-CHLOROBENZYL)-1H-INDOLE-3-CARBOXAMIDE

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1-(4-CHLORO-BENZYL)-1 H-INDOLE-3-CARBALDEHYDE AKOS B014321 CHEMBRDG-BB 5601604 ART-CHEM-BB B014321 ASISCHEM N15726 Oncrasin 1 1-[(4-Chlorophenyl)methyl]-1H-indole-3-carboxaldehyde 1-(4-chlorobenzyl)-1H-indole-3-carbaldehyde(SALTDATA: FREE) 1-[(4-chlorophenyl)methyl]-3-indolecarboxaldehyde ZERO/008607 ZINC00439476 1-[(4-chlorophenyl)methyl]indole-3-carbaldehyde 1-(4-chlorobenzyl)indole-3-carbaldehyde 1-[(4-chlorophenyl)methyl]-1H-indole-3-carbaldehyde CS-1229 Oncrasin-1 - CAS 75629-57-1 - Calbiochem Oncrasin 1 > 1H-Indole-3-carboxaldehyde, 1-[(4-chlorophenyl)methyl]- 1-(4-Chlorobenzyl)-1H-indole-3-carboxaldehyde 75629-57-1 C16H12CINO Apoptosis Inducers