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Butriptyline hydrochloride

CAS No.
5585-73-9
Chemical Name:
Butriptyline hydrochloride
Synonyms
Evadyne;AY-62014;ButriptylineHCl;Butriptylene hydrochloride;Butriptyline hydrochloride;(+/-)-10,11-Dihydro-N,N,beta-trimethyl-5H-dibenzo[a,d]cycloheptene-5-propanamine hydrochloride;(±)-[10,11-dihydro-beta-methyl-5H-dibenzo[a,d]cycloheptene-5-propyl]di(methyl)ammonium chloride;5H-Dibenzo[A,D]cycloheptene-5-propylamine, 10,11-dihydro-N,N,-.beta.-trimethyl-,hydrochloride, DL-;(2)(.+-.)-10,11-Dihydro-N,N,.beta.-trimethyl-5H-dibenzo[A,D]cycloheptene-5-propylamine hydrochloride;5H-Dibenzo[A,D]cycloheptene-5-propylamine, 10,11-dihydro-N,N,.beta.-trimethyl-, hydrochloride, (.+-.)-
CBNumber:
CB4875420
Molecular Formula:
C21H27N.ClH
Molecular Weight:
329.91
MDL Number:
MFCD00941485
MOL File:
5585-73-9.mol
Last updated:2022-12-21 16:56:50

Butriptyline hydrochloride Properties

Melting point 188-190° (dec)
FDA UNII LIJ2H8658W
NIST Chemistry Reference Butriptyline(5585-73-9)

SAFETY

Risk and Safety Statements

RIDADR  3249
HazardClass  6.1(b)
PackingGroup  III
Toxicity LD50 in mice (mg/kg): 120 i.p.; 345 orally (Voith, Herr)

Butriptyline hydrochloride price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth Carbosynth FB148401 ButriptylineHydrochloride 5585-73-9 50mg $75 2021-12-16 Buy
Biosynth Carbosynth FB148401 ButriptylineHydrochloride 5585-73-9 100mg $130 2021-12-16 Buy
Biosynth Carbosynth FB148401 ButriptylineHydrochloride 5585-73-9 250mg $260 2021-12-16 Buy
Biosynth Carbosynth FB148401 ButriptylineHydrochloride 5585-73-9 500mg $455 2021-12-16 Buy
American Custom Chemicals Corporation API0016531 BUTRIPTYLINE HYDROCHLORIDE 95.00% 5585-73-9 5MG $502.92 2021-12-16 Buy
Product number Packaging Price Buy
FB148401 50mg $75 Buy
FB148401 100mg $130 Buy
FB148401 250mg $260 Buy
FB148401 500mg $455 Buy
API0016531 5MG $502.92 Buy

Butriptyline hydrochloride Chemical Properties,Uses,Production

Originator

Evadyne,Ayerst,UK,1975

Uses

b-blocker

Manufacturing Process

A solution of dibenzo[a,e]cycloheptadiene in anhydrous xylene is added in a dropwise fashion with stirring to a suspension of sodium hydride in refluxing anhydrous xylene. The mixture is heated at reflux for two hours with continual agitation and there is then added dropwise a solution of 2-methyl-3- dimethylaminopropyl chloride in an equal volume of xylene. The mixture is then heated for fifteen hours, after which time it is cooled and decomposed by the cautious addition of ice water. The layers are separated and the aqueous layer extracted with ether. The combined organic layers are next extracted with 10% hydrochloric acid and the acidic extracts then rendered alkaline by the addition of ammonium hydroxide. The precipitated oil is extracted three times with chloroform. The chloroform extracts are dried and concentrated in vacuo, the residue being distiiled to yield the product.

Therapeutic Function

Antidepressant

Butriptyline hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Butriptyline hydrochloride Suppliers

Global( 17)Suppliers
Supplier Tel Email Country ProdList Advantage
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49391 58
Dayang Chem (Hangzhou) Co.,Ltd.
571-88938639 +8617705817739 info@dycnchem.com CHINA 52867 58
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58
GIHI CHEMICALS CO.,LIMITED
+8618058761490 info@gihichemicals.com China 50000 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24018 58
Shaanxi Dideu Newmaterial Co., Ltd. 029-63373950 15353716720 1052@dideu.com China 10011 58
Carbosynth -- sales@carbosynth.com United Kingdom 6018 58
(±)-[10,11-dihydro-beta-methyl-5H-dibenzo[a,d]cycloheptene-5-propyl]di(methyl)ammonium chloride Butriptyline hydrochloride ButriptylineHCl (+/-)-10,11-Dihydro-N,N,beta-trimethyl-5H-dibenzo[a,d]cycloheptene-5-propanamine hydrochloride AY-62014 Butriptylene hydrochloride Evadyne (2)(.+-.)-10,11-Dihydro-N,N,.beta.-trimethyl-5H-dibenzo[A,D]cycloheptene-5-propylamine hydrochloride 5H-Dibenzo[A,D]cycloheptene-5-propanamine, 10,11-dihydro-N,N,.beta.-trimethyl-, hydrochloride, (.+-.)- 5H-Dibenzo[A,D]cycloheptene-5-propylamine, 10,11-dihydro-N,N,.beta.-trimethyl-, hydrochloride, (.+-.)- 5H-Dibenzo[A,D]cycloheptene-5-propylamine, 10,11-dihydro-N,N,-.beta.-trimethyl-,hydrochloride, DL- 5585-73-9 C21H28NCl C21H27NClH