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Copper tripeptide

CAS No.
89030-95-5
Chemical Name:
Copper tripeptide
Synonyms
Copper tripeptide;GHK Copper;DEXM74;Ghk-Cu;DEX M 74;DEX M-74;DEX-M-74;GHK.CU.HAC;GHK-Cu (1:1);Ghk-Cu/AHK-CU
CBNumber:
CB52651405
Molecular Formula:
C14H21CuN6O4
Molecular Weight:
400.91
MDL Number:
MFCD09842093
MOL File:
89030-95-5.mol
Last updated:2024-05-16 17:35:26

Copper tripeptide Properties

storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility Soluble in DMSO
Sequence (Cu2+ )H-Glu-His-Lys-OH
InChIKey DDNUEECOCUBKBT-MIIMWFGWNA-L
SMILES C([C@@H]1CC2=CNC=N2[Cu+2]2NCC(=O)[N-]12)(=O)N[C@H](C(=O)[O-])CCCCN |&1:1,16,r|
EWG's Food Scores 1
FDA UNII 6BJQ43T1I9

Copper tripeptide price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC C685438 CopperPeptide(GHK-Cu) 89030-95-5 500mg $130 2021-12-16 Buy
ChemScene CS-0015088 Coppertripeptide 99.40% 89030-95-5 500mg $130 2021-12-16 Buy
Biosynth Carbosynth FC138108 Copper peptide(GHK-Cu) 89030-95-5 2g $170 2021-12-16 Buy
ChemScene CS-0015088 Coppertripeptide 99.40% 89030-95-5 250mg $90 2021-12-16 Buy
Biosynth Carbosynth FC138108 Copper peptide(GHK-Cu) 89030-95-5 1g $90 2021-12-16 Buy
Product number Packaging Price Buy
C685438 500mg $130 Buy
CS-0015088 500mg $130 Buy
FC138108 2g $170 Buy
CS-0015088 250mg $90 Buy
FC138108 1g $90 Buy

Copper tripeptide Chemical Properties,Uses,Production

Description

Copper tripeptide, also known as [N2-(N-Glycyl-L-histidyl)-L-lysinato(2-)]copper or GHK-Cu, is a naturally occurring tripeptide. It was first isolated from human plasma but can be found in saliva and urine. During wound healing, it may be freed from existing extracellular proteins via proteolysis. Studies have shown that GHK-Cu has a maximal biological effect at 10-9 mol/L and Its concentration in the body decreases with age[1].

Uses

Copper tripeptide (GHK-Cu) can be used as a skin antiaging agent. It could lead to the extracellular matrix accumulation increases in the rat wound model. Copper Peptide preparations were able to promote wound healing rates in diabetic ulcers and patients undergoing Mohs surgery. It could induce angiogenesis in rabbit models at 10?12 mol/L by acting as a chemoattractant for capillary cells. It may also improve the autocrine growth factor milieu in keloid fibroblasts[1-2]. It can also be doped into It can also be doped into binary binary PBDB-T: ITIC to tune the crystallinity and phase separation of the active layer, improving the performance of polymer solar cells[3].

Mechanism of action

At this concentration (10-9 mol/L), GHK-Cu has been shown to increase messenger RNA production for collagen, elastin, proteoglycans, and glycosaminoglycans in fibroblasts. It has been demonstrated that GHK-Cu stimulates cultured normal fibroblasts to synthesize collagen and induces a dose-dependent increase in the synthesis of glycosaminoglycans. It could stimulate the regeneration of skin, nervous tissue, bones, lungs, and liver, protect the liver from oxidative damage, restore the activity of irradiated fibroblasts, reduce inflammation, and increase levels of antioxidant enzymes[1].

Side effects

Copper tripeptide (GHK-Cu) is considered to be very safe but there are always a few side effects related to any substance that is taken for health. When using creams, you might have mild skin irritation if you are one of the very few people with sensitivity. When the substance has been injected, people have reported that they experience cramping and burning at the injection site.
Other reported side effects are: Headache; Dizziness; Fatigue; Nausea; Elevated blood pressure; Lowered blood pressure; Increase in appetite; Redness and pain at the injection site; Cramping at the injection site.

References

[1] Jeffrey D, et al. Effects of Copper Tripeptide on the Growth and Expression of Growth Factors by Normal and Irradiated Fibroblasts. Archives of Facial Plastic Surgery, 2005; 7.
[2] Huang J, et al. Efficient Ternary Polymer Solar Cells with Tunable Crystallinity and Phase Separation of Active Layers via Incorporating GHK-Cu. ACS Applied Materials Interfaces, 2021; 13: 46927–46937.
[3] Pickart L, et al.Modulation of Gene Expression in Human Breast Cancer MCF7 and Prostate Cancer PC3 Cells by the Human Copper-Binding Peptide GHK-Cu, 2021; 5.

Copper tripeptide Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 177)Suppliers
Supplier Tel Email Country ProdList Advantage
CONTIDE BIOTECH CO.,LTD
+85253358525 xena@healthtide-api.com China 594 58
Hebei Xunou new energy Technology Co., LTD
+undefined17531957005 xunou8@hbxunou.com China 36 58
BOC Sciences
+16314854226 inquiry@bocsci.com United States 19743 58
zhuzhou dingcheng meihei comestic co.,ltd
+undefined18873369619 dingchengbusiness8@163.com China 242 58
Hubei Yuanao Technology CO Ltd
+86-15377628618 +86-15377628618 info@yuanaotech.com China 6 58
Sichuan HongRi Pharma-Tech Co.,Ltd
+86-028-64841719 +8615680023009 daisy@enlaibio.com China 1369 58
Zhejiang Hangyu API Co., Ltd
+8617531972939 anna@api-made.com China 2944 58
hebei hongtan Biotechnology Co., Ltd
+86-86-1913198-3935 +8617331935328 sales03@chemcn.cn China 952 58
ZHEJIANG JIUZHOU CHEM CO., LTD
+86-0576225566889 +86-13454675544 admin@jiuzhou-chem.com;jamie@jiuzhou-chem.com;alice@jiuzhou-chem.com China 19949 58
Shanghai Chinqesen Biotechnology Co., Ltd.
+86-16628886292 +86-19521323435 sales2@qschem-pharma.com China 46 58

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  • Apr 22,2024

View Lastest Price from Copper tripeptide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
?GHK-Cu pictures 2024-05-17 ?GHK-Cu
89030-95-5
US $55.00-40.00 / box 1box 99.99% 1000 hebei hongtan Biotechnology Co., Ltd
GHK-Cu pictures 2024-05-17 GHK-Cu
89030-95-5
US $55.00-40.00 / BOX 1BOX 99% 1000 hebei hongtan Biotechnology Co., Ltd
GHK-Cu.hcl pictures 2024-05-17 GHK-Cu.hcl
89030-95-5
US $0.00-0.00 / kg 1kg 98+ 1T Sichuan HongRi Pharma-Tech Co.,Ltd
  • ?GHK-Cu pictures
  • ?GHK-Cu
    89030-95-5
  • US $55.00-40.00 / box
  • 99.99%
  • hebei hongtan Biotechnology Co., Ltd
  • GHK-Cu pictures
  • GHK-Cu
    89030-95-5
  • US $55.00-40.00 / BOX
  • 99%
  • hebei hongtan Biotechnology Co., Ltd
  • GHK-Cu.hcl pictures
  • GHK-Cu.hcl
    89030-95-5
  • US $0.00-0.00 / kg
  • 98+
  • Sichuan HongRi Pharma-Tech Co.,Ltd
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