[N2-(N-글리실-L-히스티딜)-L-리시나토(2-)]구리

[N2-(N-글리실-L-히스티딜)-L-리시나토(2-)]구리
[N2-(N-글리실-L-히스티딜)-L-리시나토(2-)]구리 구조식 이미지
카스 번호:
89030-95-5
한글명:
[N2-(N-글리실-L-히스티딜)-L-리시나토(2-)]구리
동의어(한글):
[N2-(N-글리실-L-히스티딜)-L-리시나토(2-)]구리
상품명:
Copper tripeptide
동의어(영문):
Copper tripeptide;GHK Copper;DEXM74;Ghk-Cu;DEX M 74;DEX M-74;DEX-M-74;GHK.CU.HAC;GHK-Cu (1:1);Ghk-Cu/AHK-CU
CBNumber:
CB52651405
분자식:
C14H21CuN6O4
포뮬러 무게:
400.91
MOL 파일:
89030-95-5.mol

[N2-(N-글리실-L-히스티딜)-L-리시나토(2-)]구리 속성

저장 조건
under inert gas (nitrogen or Argon) at 2–8 °C
용해도
DMSO에 용해됨
시퀀스
(Cu2+ )H-Glu-His-Lys-OH
InChIKey
DDNUEECOCUBKBT-MIIMWFGWNA-L
SMILES
C([C@@H]1CC2=CNC=N2[Cu+2]2NCC(=O)[N-]12)(=O)N[C@H](C(=O)[O-])CCCCN |&1:1,16,r|

안전

[N2-(N-글리실-L-히스티딜)-L-리시나토(2-)]구리 C화학적 특성, 용도, 생산

개요

Copper tripeptide, also known as [N2-(N-Glycyl-L-histidyl)-L-lysinato(2-)]copper or GHK-Cu, is a naturally occurring tripeptide. It was first isolated from human plasma but can be found in saliva and urine. During wound healing, it may be freed from existing extracellular proteins via proteolysis. Studies have shown that GHK-Cu has a maximal biological effect at 10-9 mol/L and Its concentration in the body decreases with age[1].

용도

Copper tripeptide (GHK-Cu) can be used as a skin antiaging agent. It could lead to the extracellular matrix accumulation increases in the rat wound model. Copper Peptide preparations were able to promote wound healing rates in diabetic ulcers and patients undergoing Mohs surgery. It could induce angiogenesis in rabbit models at 10?12 mol/L by acting as a chemoattractant for capillary cells. It may also improve the autocrine growth factor milieu in keloid fibroblasts[1-2]. It can also be doped into It can also be doped into binary binary PBDB-T: ITIC to tune the crystallinity and phase separation of the active layer, improving the performance of polymer solar cells[3].

부작용

Copper tripeptide (GHK-Cu) is considered to be very safe but there are always a few side effects related to any substance that is taken for health. When using creams, you might have mild skin irritation if you are one of the very few people with sensitivity. When the substance has been injected, people have reported that they experience cramping and burning at the injection site.
Other reported side effects are: Headache; Dizziness; Fatigue; Nausea; Elevated blood pressure; Lowered blood pressure; Increase in appetite; Redness and pain at the injection site; Cramping at the injection site.

[N2-(N-글리실-L-히스티딜)-L-리시나토(2-)]구리 준비 용품 및 원자재

원자재

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