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CID5721353

CAS No.
301356-95-6
Chemical Name:
CID5721353
Synonyms
CID5721353;BCL6 inhibitor;79-6(CID5721353);CID-5721353;CID 5721353;CID5721353 BDL6 inhribitor;BCL6 inhibitor(CID5721353);CID5721353, BCL6 inhibitor;79-6 (CID5721353, BCL6 inhibitor);CID 5721353;CID-5721353;CID 5721353;Apoptosis,Inhibitor,CID5721353,Bcl-2 Family,CID-5721353,inhibit,CID 5721353
CBNumber:
CB53159456
Molecular Formula:
C15H9BrN2O6S2
Molecular Weight:
457.28
MDL Number:
MFCD31729277
MOL File:
301356-95-6.mol
Last updated:2023-05-21 10:59:17

CID5721353 Properties

Density 2.06±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
pka 3.02±0.23(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

CID5721353 price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 22967 CID-5721353 301356-95-6 1mg $32 2024-03-01 Buy
Cayman Chemical 22967 CID-5721353 301356-95-6 5mg $70 2024-03-01 Buy
Cayman Chemical 22967 CID-5721353 301356-95-6 10mg $109 2024-03-01 Buy
Cayman Chemical 22967 CID-5721353 301356-95-6 25mg $190 2024-03-01 Buy
AK Scientific 6486CL 2-[5-(5-Bromo-2-oxoindol-3-yl)-4-hydroxy-2-sulfanylidene-1,3-thiazol-3-yl]butanedioicacid 301356-95-6 5mg $313 2021-12-16 Buy
Product number Packaging Price Buy
22967 1mg $32 Buy
22967 5mg $70 Buy
22967 10mg $109 Buy
22967 25mg $190 Buy
6486CL 5mg $313 Buy

CID5721353 Chemical Properties,Uses,Production

Description

CID-5721353 is an inhibitor of the transcriptional repressor B cell lymphoma 6 (Bcl-6; Ki = 147 μM). It is selective for Bcl-6 over Kaiso, hypermethylated in cancer 1 (HIC1), and promyelocytic leukemia zinc finger (PLZF) at 50 μM. CID-5721353 is cytotoxic against Bcl-6-dependent SU-DLH-6, SU-DLH-4, Farage, OCI-LY7, OCI-LY1, and OCI-LY10 diffuse large B cell lymphoma (DLBCL) cells (GI50s = 0.024-0.936 mM) but not Bcl-6-independent Toledo or OCI-LY4 DLBCL cells (GI50 = >15 mM for both). It increases expression of the Bcl-6 target genes ATR, TP53, CD69, p21, and CD44 in SU-DLH-6 and SU-DHL-4 cells when used at a concentration of 50 μM. CID-5721353 (50 mg/kg) reduces tumor growth in OCI-LY7 and SU-DHL-6 mouse xenograft models.

CID5721353 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 49)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32686 60
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
+86-021-61551413 +8618813727289 contact@trustwe.com China 5738 58
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd
+86-86-22-87899925 +86-8618522618860 18522618860@163.com China 694 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10523 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58
ShenZhen Trendseen Biological Technology Co.,Ltd.
13417589054 trendseenbio@gmail.com China 11681 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 57511 58

View Lastest Price from CID5721353 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
CID5721353 pictures 2019-12-26 CID5721353
301356-95-6
US $1.00 / KG 1KG 97%-99.9% 100kg Career Henan Chemical Co
  • CID5721353 pictures
  • CID5721353
    301356-95-6
  • US $1.00 / KG
  • 97%-99.9%
  • Career Henan Chemical Co
CID5721353 CID5721353, BCL6 inhibitor BCL6 inhibitor(CID5721353) CID5721353 BDL6 inhribitor CID-5721353;CID 5721353 79-6 (CID5721353, BCL6 inhibitor) CID 5721353;CID-5721353;CID 5721353 2-(5-(5-bromo-2-oxoindolin-3-ylidene)-4-oxo-2-thioxothiazolidin-3-yl)succinic acid BCL6 inhibitor Butanedioic acid, 2-[5-(5-bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinyl]- Apoptosis,Inhibitor,CID5721353,Bcl-2 Family,CID-5721353,inhibit,CID 5721353 79-6(CID5721353) 301356-95-6 C15H9BrN2O6S2 API