ChemicalBook >> CAS DataBase List >>CID5721353
CID5721353
- CAS No.
- 301356-95-6
- Chemical Name:
- CID5721353
- Synonyms
- CID5721353;BCL6 inhibitor;79-6(CID5721353);CID-5721353;CID 5721353;CID5721353 BDL6 inhribitor;BCL6 inhibitor(CID5721353);CID5721353, BCL6 inhibitor;79-6 (CID5721353, BCL6 inhibitor);CID 5721353;CID-5721353;CID 5721353;Apoptosis,Inhibitor,CID5721353,Bcl-2 Family,CID-5721353,inhibit,CID 5721353
- CBNumber:
- CB53159456
- Molecular Formula:
- C15H9BrN2O6S2
- Molecular Weight:
- 457.28
- MDL Number:
- MFCD31729277
- MOL File:
- 301356-95-6.mol
Last updated:2023-05-21 10:59:17
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
CID5721353 price More Price(8)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 22967 | CID-5721353 | 301356-95-6 | 1mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 22967 | CID-5721353 | 301356-95-6 | 5mg | $70 | 2024-03-01 | Buy |
Cayman Chemical | 22967 | CID-5721353 | 301356-95-6 | 10mg | $109 | 2024-03-01 | Buy |
Cayman Chemical | 22967 | CID-5721353 | 301356-95-6 | 25mg | $190 | 2024-03-01 | Buy |
AK Scientific | 6486CL | 2-[5-(5-Bromo-2-oxoindol-3-yl)-4-hydroxy-2-sulfanylidene-1,3-thiazol-3-yl]butanedioicacid | 301356-95-6 | 5mg | $313 | 2021-12-16 | Buy |
CID5721353 Chemical Properties,Uses,Production
Description
CID-5721353 is an inhibitor of the transcriptional repressor B cell lymphoma 6 (Bcl-6; Ki = 147 μM). It is selective for Bcl-6 over Kaiso, hypermethylated in cancer 1 (HIC1), and promyelocytic leukemia zinc finger (PLZF) at 50 μM. CID-5721353 is cytotoxic against Bcl-6-dependent SU-DLH-6, SU-DLH-4, Farage, OCI-LY7, OCI-LY1, and OCI-LY10 diffuse large B cell lymphoma (DLBCL) cells (GI50s = 0.024-0.936 mM) but not Bcl-6-independent Toledo or OCI-LY4 DLBCL cells (GI50 = >15 mM for both). It increases expression of the Bcl-6 target genes ATR, TP53, CD69, p21, and CD44 in SU-DLH-6 and SU-DHL-4 cells when used at a concentration of 50 μM. CID-5721353 (50 mg/kg) reduces tumor growth in OCI-LY7 and SU-DHL-6 mouse xenograft models.
CID5721353 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 49)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd | +86-86-22-87899925 +86-8618522618860 | 18522618860@163.com | China | 694 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
View Lastest Price from CID5721353 manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2019-12-26 | CID5721353
301356-95-6
|
US $1.00 / KG | 1KG | 97%-99.9% | 100kg | Career Henan Chemical Co |
- CID5721353
301356-95-6
- US $1.00 / KG
- 97%-99.9%
- Career Henan Chemical Co
CID5721353
CID5721353, BCL6 inhibitor
BCL6 inhibitor(CID5721353)
CID5721353 BDL6 inhribitor
CID-5721353;CID 5721353
79-6 (CID5721353, BCL6 inhibitor)
CID 5721353;CID-5721353;CID 5721353
2-(5-(5-bromo-2-oxoindolin-3-ylidene)-4-oxo-2-thioxothiazolidin-3-yl)succinic acid
BCL6 inhibitor
Butanedioic acid, 2-[5-(5-bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinyl]-
Apoptosis,Inhibitor,CID5721353,Bcl-2 Family,CID-5721353,inhibit,CID 5721353
79-6(CID5721353)
301356-95-6
C15H9BrN2O6S2
API