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RAS INHIBITORY PEPTIDE

CAS No.
159088-48-9
Chemical Name:
RAS INHIBITORY PEPTIDE
Synonyms
VPPPVPPRRR-NH2;RAS INHIBITORY PEPTIDE;Sos SH3 domain inhibitor;Sos SH3 domain inhibitor inhibitor;VAL-PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG;HSOS (1149-1158) N10 SH3 BINDING DOMAIN;H-VAL-PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG-OH;L-Arginine, L-valyl-L-prolyl-L-prolyl-L-prolyl-L-valyl-L-prolyl-L-prolyl-L-arginyl-L-arginyl-
CBNumber:
CB5356014
Molecular Formula:
C53H91N19O11
Molecular Weight:
1170.41
MDL Number:
MFCD00237248
MOL File:
159088-48-9.mol
Last updated:2023-05-18 11:31:15

RAS INHIBITORY PEPTIDE Properties

Density 1.52±0.1 g/cm3(Predicted)
storage temp. −20°C
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: Miscible; PBS (pH 7.2): 10 mg/ml
form A crystalline solid
pka 3.31±0.10(Predicted)

SAFETY

Risk and Safety Statements

WGK Germany  3

RAS INHIBITORY PEPTIDE price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 17474 Ras Inhibitory Peptide ≥95% 159088-48-9 500μg $68 2024-03-01 Buy
Cayman Chemical 17474 Ras Inhibitory Peptide ≥95% 159088-48-9 1mg $116 2024-03-01 Buy
Cayman Chemical 17474 Ras Inhibitory Peptide ≥95% 159088-48-9 5mg $502 2024-03-01 Buy
Cayman Chemical 17474 Ras Inhibitory Peptide ≥95% 159088-48-9 10mg $869 2024-03-01 Buy
Usbiological R1198-40 Ras Inhibitory Peptide 159088-48-9 1mg $531 2021-12-16 Buy
Product number Packaging Price Buy
17474 500μg $68 Buy
17474 1mg $116 Buy
17474 5mg $502 Buy
17474 10mg $869 Buy
R1198-40 1mg $531 Buy

RAS INHIBITORY PEPTIDE Chemical Properties,Uses,Production

Description

Son of sevenless homolog 1 (Sos1) is a guanine nucleotide exchange factor (GEF) that directs the exchange of Ras-GDP to Ras-GTP by binding to SH3 domains of the growth factor receptor-bound protein 2 (Grb2), leading to the activation of ERK. Ras inhibitory peptide is a synthetic peptide that contains the sequence PVPPR, which corresponds to a region within human Sos1 that interacts with an SH3 domain of Grb2. It specifically blocks the interaction of the GEF with Grb2, preventing an interaction that is essential for Ras activation by receptor tyrosine kinases, including epidermal growth factor receptor.

RAS INHIBITORY PEPTIDE Preparation Products And Raw materials

Raw materials

Preparation Products

RAS INHIBITORY PEPTIDE Suppliers

Global( 47)Suppliers
Supplier Tel Email Country ProdList Advantage
Shenzhen Nexconn Pharmatechs Ltd
+86-755-89396905 +86-15013857715 admin@nexconn.com China 10247 58
Zhejiang Hangyu API Co., Ltd
+8617531972939 anna@api-made.com China 2944 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
GL Biochem (Shanghai) Ltd 21-61263452 13641803416 ymbetter@glbiochem.com China 9981 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42982 64
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15421 60
Hangzhou Peptidego Biotech Co.,Ltd. 0571-87213919 eric@peptidego.com China 6347 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
Nanjing Meihao Pharmaceutical Technology Co., Ltd. meitaochem@126.com meitaochem@126.com China 19105 58
BOC Sciences -- info@bocsci.com USA 0 65

159088-48-9(RAS INHIBITORY PEPTIDE)Related Search:

RAS INHIBITORY PEPTIDE VPPPVPPRRR-NH2 VAL-PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG H-VAL-PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG-OH HSOS (1149-1158) N10 SH3 BINDING DOMAIN Sos SH3 domain inhibitor L-Arginine, L-valyl-L-prolyl-L-prolyl-L-prolyl-L-valyl-L-prolyl-L-prolyl-L-arginyl-L-arginyl- Sos SH3 domain inhibitor inhibitor 159088-48-9 C53H91N19O11 BioChemical Cell Signaling and Neuroscience Cell Biology Reagents G Protein Function G Proteins and Cyclic Nucleotides