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(R)-N-Boc-glutamic acid-1,5-dimethyl ester

(R)-N-Boc-glutamic acid-1,5-dimethyl ester structure

CAS No.: 59279-60-6

Chemical Name:: (R)-N-Boc-glutamic acid-1,5-dimethyl ester

Synonyms: N-Boc-L-Glutamic acid dimethyl ester;BOC-GLU(OME)-OME;BOC-L-GLU(OME)-OME;Dimethyl N-(tert-Butoxycarbonyl)-L-glutamate;BOC-GLU(OME)-OME 45G;BOC-L-GLUTAMIC ACID DIMETHYL ESTER;dimethyl(tert-butoxycarbonyl)-L-glutamate;(S)-diMethyl 2-(tert-butoxycarbonylaMino)pentanedioate;BOC-L-GLU(ME)-OME;Dimethyl (2S)-2-(tert-butoxycarbonylamino)pentanedioate

CBNumber:: CB5853917

Molecular Formula:: C12H21NO6

Molecular Weight:: 275.3

MDL Number:: MFCD03094774

MOL File:: 59279-60-6.mol

MSDS File:: SDS

Last updated:2024-03-26 11:13:42

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(R)-N-Boc-glutamic acid-1,5-dimethyl ester Properties

Melting point	43.0 to 47.0 °C
Boiling point	370.9±32.0 °C(Predicted)
Density	1.117±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), DMSO (Slightly)
pka	10.86±0.46(Predicted)
form	Liquid
color	Colorless to pale yellow
CAS DataBase Reference	59279-60-6(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H332-H335

Precautionary statements

P261-P280-P305+P351+P338

HS Code

2922420090

NFPA 704

	0
0		0

(R)-N-Boc-glutamic acid-1,5-dimethyl ester price More Price(41)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	D4536	Dimethyl N-(tert-Butoxycarbonyl)-L-glutamate >98.0%(HPLC)(N)	59279-60-6	1g	$30	2024-03-01	Buy
TCI Chemical	D4536	Dimethyl N-(tert-Butoxycarbonyl)-L-glutamate >98.0%(HPLC)(N)	59279-60-6	5g	$87	2024-03-01	Buy
Alfa Aesar	H62056	N-Boc-L-glutamic acid 1,5-dimethyl ester, 97%	59279-60-6	5g	$62.65	2024-03-01	Buy
Alfa Aesar	H62056	N-Boc-L-glutamic acid 1,5-dimethyl ester, 97%	59279-60-6	25g	$260.65	2024-03-01	Buy
TRC	B600185	N-Boc-L-glutamicAcid1,5-DimethylEster	59279-60-6	5g	$80	2021-12-16	Buy

Product number	Packaging	Price	Buy
D4536	1g	$30	Buy
D4536	5g	$87	Buy
H62056	5g	$62.65	Buy
H62056	25g	$260.65	Buy
B600185	5g	$80	Buy

(R)-N-Boc-glutamic acid-1,5-dimethyl ester Chemical Properties,Uses,Production

Uses

(R)-N-Boc-glutamic acid-1,5-dimethyl ester can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development and chemical production processes.

Synthesis

Synthesis_59279-60-6
L-glutamic acid (10.0 g, 67.97 mmol) was dissolved in 200 mL of methanol, and SOCl2(10.85 mL, 149.53 mmol)was slowly added dropwise under an ice bath. After the addition, reflux was performed at 65 ?? C. After 2 hours, the reaction system was cooled to room temperature, and methanol was evaporated to dryness under reduced pressure to obtain a colorless viscous substance.This colorless viscous substance was dissolved in 200 mL of THF, (Boc)2O (22.25 g, 101.95 mmol) was addedunder an ice bath, and triethylamine (14.13 mL, 101.95 mmol) was slowly added dropwise.After the addition was complete, the reaction was allowed to proceed at room temperature overnight.After completion of the reaction, the solvent was distilled off under reduced pressure.The residue was dissolved in 200 mL of dichloromethane.The organic phase was washed with water (200 mL * 2), saturated citric acid solution (200 mL * 2), saturated sodium bicarbonate solution (200 mL * 2), and saturated brine (200 mL * 2) in that order.The organic phase was dried over anhydrous Na2SO4. Thefiltrate was collected by filtration, and the solvent was evaporated under reduced pressure. The residue was purified by column chromatography (petroleum ether: ethyl acetate = 4: 1 v / v) to give a colorless oily product (R)-N-Boc-glutamic acid-1,5-dimethyl ester (18.34 g, yield 98%)

(R)-N-Boc-glutamic acid-1,5-dimethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

(R)-N-Boc-glutamic acid-1,5-dimethyl ester Suppliers

Global( 317)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49391	58
AstaTech(Chengdu) Biopharmaceutical Corp.	+86-02882666559 +86-15884417729	gjpu@astatech.com.cn	China	308	58
WinWin Chemical CO., Limited	+86-0577-64498589 +8615325081899	sales@win-winchemical.com	China	14151	58
weifang runzhong fine chemical co., ltd	536-7868377 +8618653686003	sq@runzhongchem.com	China	187	58
Ningxia LabsChem Co., Ltd.	0952-9294929 +8613895679378	48472788@qq.com	China	352	58
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12470	58
Firsky International Trade (Wuhan) Co., Ltd	+8615387054039	admin@firsky-cn.com	China	436	58
Anhui Ruihan Technology Co., Ltd	+8617756083858	daisy@anhuiruihan.com	China	994	58
Sichuan HongRi Pharma-Tech Co.,Ltd	+86-028-64841719 +8615680023009	daisy@enlaibio.com	China	1369	58
Chongqing Zhihe Biopharmaceutical Co., Ltd.	+86-18580541567 +86-17782035140	sales@zhswyy.com	China	242	58

Supplier	Advantage
CONIER CHEM AND PHARMA LIMITED	58
AstaTech(Chengdu) Biopharmaceutical Corp.	58
WinWin Chemical CO., Limited	58
weifang runzhong fine chemical co., ltd	58
Ningxia LabsChem Co., Ltd.	58
Hebei Mojin Biotechnology Co., Ltd	58
Firsky International Trade (Wuhan) Co., Ltd	58
Anhui Ruihan Technology Co., Ltd	58
Sichuan HongRi Pharma-Tech Co.,Ltd	58
Chongqing Zhihe Biopharmaceutical Co., Ltd.	58

View Lastest Price from (R)-N-Boc-glutamic acid-1,5-dimethyl ester manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-05-11	(R)-N-Boc-glutamic acid-1,5-dimethyl ester 59279-60-6	US $0.00-0.00 / kg	0.10000000149011612kg	99	20tons	Chongqing Zhihe Biopharmaceutical Co., Ltd.
2024-05-11	Boc-L-Glu(Ome)-Ome 59279-60-6	US $0.00-0.00 / kg	1kg	98%	1T+	Sichuan HongRi Pharma-Tech Co.,Ltd
2024-01-08	(R)-N-Boc-glutamic acid-1,5-dimethyl ester 59279-60-6	US $32.00 / KG	1KG	99.9	200	Wuhan Boyuan Import & Export Co., LTD

(R)-N-Boc-glutamic acid-1,5-dimethyl ester
59279-60-6
US $0.00-0.00 / kg
99
Chongqing Zhihe Biopharmaceutical Co., Ltd.

Boc-L-Glu(Ome)-Ome
59279-60-6
US $0.00-0.00 / kg
98%
Sichuan HongRi Pharma-Tech Co.,Ltd

(R)-N-Boc-glutamic acid-1,5-dimethyl ester
59279-60-6
US $32.00 / KG
99.9
Wuhan Boyuan Import & Export Co., LTD

59279-60-6((R)-N-Boc-glutamic acid-1,5-dimethyl ester)Related Search:

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1of4

Dimethyl N-(tert-Butoxycarbonyl)-L-glutamate N-ALPHA-TERT-BUTYLOXYCARBONYL-L-GLUTAMIC ACID DI-METHYL DIESTER N-ALPHA-T-BUTYLOXYCARBONYL-L-GLUTAMIC ACID DIMETHYL DIESTER N-ALPHA-T-BUTOXYCARBONYL-L-GLUTAMIC ACID ALPHA, GAMMA-DIMETHYL ESTER (R)-N-BOC-GLUTAMIC ACID-1,5-DIMETHYL ESTER (S)-2-tert-ButoxycarbonylaMinopentanedioic acid diMethyl ester N-alpha-t-Butyloxycarbonyl-L-glutamic acid di-methyl ester Dimethyl (2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanedioate N-Boc-L-GlutaMic Acid diMethyl ester/(S)-2-tert-ButoxycarbonylaMino-pentanedioic acid diMethyl ester (S)-2-tert-ButoxycarbonylaMino-pentanedioic acid diMethyl ester N-Boc-L-glutaMic acid 1,5-diMethyl ester, 97% N-α-(t-Butoxycarbonyl)-L-glutamic acid α,γ-dimethyl ester (R)-N-Boc-glutamic acid-1,5-dimethyl ester （PF-07321332 Paxlovid intermediate） Dimethyl Boc-Glutamate 59279-60-6---(R)-N-Boc-glutamic acid-1,5-dimethyl ester 1,5-dimethyl (2S)-2-{[(tert-butoxy)carbonyl]amino}pentanedioate (R)-N-Boc-glutamic acid-1，5-dinethyl ester (Tert-Butoxy)Carbonyl Glu(OMe)-OMe (Syrup) Dimethyl N-(tert-Butoxycarbonyl)-L-glutamate > u(Ome)-OMe L-Glutamic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 1,5-dimethyl ester imethyl(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanedioate N-(tert-Butoxycarbonyl)-L-glutamic Acid Dimethyl Ester Dimethyl N-Boc-L-glutamate (R)-N-Boc-glutamic acid-1,5-dimethyl ester USP/EP/BP Boc-Glu-OMe(OMe) USP/EP/BP BOC-L-GLU(OME)-OME BOC-L-GLUTAMIC ACID DIMETHYL ESTER BOC-GLU(OME)-OME BOC-GLU(OME)-OME 45G N-Boc-L-Glutamic acid dimethyl ester BOC-L-GLU(ME)-OME (S)-diMethyl 2-(tert-butoxycarbonylaMino)pentanedioate Dimethyl N-(tert-Butoxycarbonyl)-L-glutamate dimethyl(tert-butoxycarbonyl)-L-glutamate Dimethyl (2S)-2-(tert-butoxycarbonylamino)pentanedioate 1,5-Dimethyl N-[(1,1-dimethylethoxy)carbonyl]-L-glutamate N-Boc-L-glutamic acid 1,5-dimethyl Dimethyl (S)-(N-tert-butoxycarbonyl)glutamate (R)-N-Boc-glutamic acid-1,5-dimethyl este 59279-60-6 59579-60-6 52979-60-6 1