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marinobufagenin

CAS No.
470-42-8
Chemical Name:
marinobufagenin
Synonyms
Marinobufagin;Marinobufogenin;marinobufagenin;Marinobufagin(Marinobufagenin);3β,5β-Dihydroxy-14β,15β-epoxybufa-20,22-dienolide;3β,5-Dihydroxy-14,15β-epoxy-5β-bufa-20,22-dienolide;14,15β-Epoxy-3β,5-dihydroxy-5β-bufa-20,22-dienolide;(3β,5β,15β)-3,5-Dihydroxy-14,15-epoxybufa-20,22-dienolide;Bufa-20,22-dienolide, 14,15-epoxy-3,5-dihydroxy-, (3β,5β,15β)-;5-((1R,2aR,3aS,3bR,5aS,7S,9aR,9bS,11aR)-5a,7-dihydroxy-9a,11a-dimethylhexadecahydronaphtho[1',2':6,7]indeno[1,7a-b]oxiren-1-yl)-2H-pyran-2-one
CBNumber:
CB61360037
Molecular Formula:
C24H32O5
Molecular Weight:
400.52
MDL Number:
MFCD32661898
MOL File:
470-42-8.mol
MSDS File:
SDS
Last updated:2023-05-21 10:59:17

marinobufagenin Properties

Melting point 224-225 °C
Boiling point 589.0±50.0 °C(Predicted)
Density 1.31±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 3 mg/ml; DMF:PBS (pH 7.2) (1:8): 0.1 mg/ml; Ethanol: 1 mg/ml
form A crystalline solid
pka 14.77±0.70(Predicted)
FDA UNII 3KBT25GV2B

marinobufagenin price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 20798 Marinobufagenin ≥98% 470-42-8 500μg $57 2024-03-01 Buy
Cayman Chemical 20798 Marinobufagenin ≥98% 470-42-8 1mg $107 2024-03-01 Buy
Cayman Chemical 20798 Marinobufagenin ≥98% 470-42-8 5mg $467 2024-03-01 Buy
Biosynth Carbosynth FM167440 Marinobufagenin 470-42-8 5mg $550 2021-12-16 Buy
Medical Isotopes, Inc. 73875 Marinobufagin 98% 470-42-8 5mg $590 2021-12-16 Buy
Product number Packaging Price Buy
20798 500μg $57 Buy
20798 1mg $107 Buy
20798 5mg $467 Buy
FM167440 5mg $550 Buy
73875 5mg $590 Buy

marinobufagenin Chemical Properties,Uses,Production

Uses

Marinobufagin is a bufadienolide with anti-gastric cancer effect. A bioactive steroid that also functions as an endogenous Na/K-ATPase bufadienolide inhibitor that plays a major role in human cardiovascular diseases.

Definition

ChEBI: Marinobufagenin is a cardiotonic steroid secreted by the toad Bufo rubescens and other related species such as Bufo marinus. An endogenous Na/K-ATPase inhibitor, it is a vasoconstrictor with effects similar to digitalis. It has a role as an EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor and an epitope. It is a steroid hormone and an epoxy steroid. It is functionally related to a (5beta)-bufadienolide.

marinobufagenin Preparation Products And Raw materials

Raw materials

Preparation Products

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Nanjing Endesa Bio-tech Co., Ltd. 025-58862853 18915922038 sales@endesachem.com China 592 58
marinobufagenin 14,15β-Epoxy-3β,5-dihydroxy-5β-bufa-20,22-dienolide 3β,5-Dihydroxy-14,15β-epoxy-5β-bufa-20,22-dienolide 3β,5β-Dihydroxy-14β,15β-epoxybufa-20,22-dienolide Marinobufagin Marinobufogenin (3β,5β,15β)-3,5-Dihydroxy-14,15-epoxybufa-20,22-dienolide Bufa-20,22-dienolide, 14,15-epoxy-3,5-dihydroxy-, (3β,5β,15β)- Marinobufagin(Marinobufagenin) 5-((1R,2aR,3aS,3bR,5aS,7S,9aR,9bS,11aR)-5a,7-dihydroxy-9a,11a-dimethylhexadecahydronaphtho[1',2':6,7]indeno[1,7a-b]oxiren-1-yl)-2H-pyran-2-one 470-42-8 Vasoconstrictor Agents Enzyme Inhibitors