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(1S,2S,3S)-Aprepitant

CAS No.
1242175-40-1
Chemical Name:
(1S,2S,3S)-Aprepitant
Synonyms
Aprepitant Impurity 5;Aprepitant iMpurity 30;Aprepitant (S,S,S)-Isomer;Aprepitant Impurity 7(S,S,S-Isomer);Arepitam impurity isomers (1S, 2S, 3S);Aprepitant impurity 10/(S,S,S)-Aprepitant;3H-1,2,4-Triazol-3-one, 5-[[(2S,3S)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-
CBNumber:
CB63146510
Molecular Formula:
C23H21F7N4O3
Molecular Weight:
534.43
MDL Number:
MOL File:
1242175-40-1.mol
Last updated:2023-05-15 10:43:46

(1S,2S,3S)-Aprepitant price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC A729780 (S,S,S)-Aprepitant 1242175-40-1 10mg $1050 2021-12-16 Buy
Product number Packaging Price Buy
A729780 10mg $1050 Buy

(1S,2S,3S)-Aprepitant Chemical Properties,Uses,Production

Uses

(S,S,S)-Aprepitant is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic.

(1S,2S,3S)-Aprepitant Preparation Products And Raw materials

Raw materials

Preparation Products

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Aprepitant Impurity 5 Aprepitant impurity 10/(S,S,S)-Aprepitant Arepitam impurity isomers (1S, 2S, 3S) Aprepitant (S,S,S)-Isomer Aprepitant Impurity 7(S,S,S-Isomer) Aprepitant iMpurity 30 3H-1,2,4-Triazol-3-one, 5-[[(2S,3S)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro- 1242175-40-1