ChemicalBook >> CAS DataBase List >>Mosapride citrate
Mosapride citrate
- CAS No.
- 112885-42-4
- Chemical Name:
- Mosapride citrate
- Synonyms
- as4370;Gasmotin;enzamidecitrate;AS-4370 citrate;TAK-370 citrate;MOSAPRIDE CITRATE;Mosapride citrate,>99%;Mosapride Citrate (TAK-370;Mosapride citrate USP/EP/BP;Mosapridecitrate/TAK-370citrate/AS-4370citrate
- CBNumber:
- CB6696030
- Molecular Formula:
- C27H33ClFN3O10
- Molecular Weight:
- 614.02
- MDL Number:
- MFCD00874415
- MOL File:
- 112885-42-4.mol
- MSDS File:
- SDS
Last updated:2023-06-30 15:45:59
| Melting point | 143-145° |
|---|---|
| storage temp. | Inert atmosphere,2-8°C |
| solubility | DMSO (Slightly), Ethanol (Slightly, Sonicated) |
| form | Solid |
| color | White to Off-White |
| Stability | Hygroscopic |
| CAS DataBase Reference | 112885-42-4(CAS DataBase Reference) |
| FDA UNII | MF497J489P |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H332-H335 | |||||||||
| Precautionary statements | P280-P305+P351+P338-P310 | |||||||||
| Toxicity | LD50 in male, female mice, rats (mg/kg): >3000, >3000, >3000, 1905 orally; >1000, 914, >1000, >1000 i.p.; all species >1000 s.c.; in male, female dogs (mg/kg): both >400 orally (Yatera) | |||||||||
| NFPA 704 |
|
Mosapride citrate price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 30048 | Mosapride (citrate) | 112885-42-4 | 10mg | $57 | 2024-03-01 | Buy |
| Cayman Chemical | 30048 | Mosapride (citrate) | 112885-42-4 | 250mg | $887 | 2024-03-01 | Buy |
| Cayman Chemical | 30048 | Mosapride (citrate) | 112885-42-4 | 50mg | $208 | 2024-03-01 | Buy |
| Cayman Chemical | 30048 | Mosapride (citrate) | 112885-42-4 | 100mg | $384 | 2024-03-01 | Buy |
| Tocris | 2844 | Mosapridecitrate ≥99%(HPLC) | 112885-42-4 | 50 | $459 | 2021-12-16 | Buy |
Mosapride citrate Chemical Properties,Uses,Production
Description
Mosapride is an agonist of the serotonin (5-HT) receptor subtype 5-HT4 (Ki = 69.9 nM). It is selective for 5-HT4 over 5-HT1, 5-HT2, dopamine D2, and α1- and α2-adrenergic receptors but acts as a partial antagonist at 5-HT3 (Ki = 1,189 nM). It induces relaxation of precontracted rat esophageal thoracic muscularis mucosa preparations and enhances electrically evoked contractions in isolated guinea pig ileum (EC50s = 208.4 and 73.2 nM, respectively). Mosapride (0.5 and 1 mg/kg, i.v.) increases antral and duodenal, but not ileal or colonic, motility in conscious dogs. It also increases gastric emptying in rats when administered at doses ranging from 0.03 to 30 mg/kg.
Uses
Mosapride Citrate is a selective SR-4 activator and a SR-3 inhibitor.
Uses
As a selective SR-4 activator and a SR-3 inhibitor, Mosapride(Mosapride citrate) is a gastroprokinetic agent that acts as a selective 5HT4 agonist which accelerates gastric emptying and is used for the treatment of acid reflux, irritable bowel syndrome and functional dyspepsia.
Biological Activity
5-HT 4 receptor agonist and 5-HT 3 receptor antagonist. Displays no activity at D 2 , α 1 , α 2 , 5-HT 1 and 5-HT 2 receptors. Gastroprokinetic agent; increases gastric emptying in rats and stimulates gastric motor actvity in conscious dogs.
storage
room temperature (desiccate)
Mosapride citrate Preparation Products And Raw materials
Global( 287)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chongqing Ensky Pharmaceutical Co.,Ltd. | +86-23-86815286 +86-13983794297 | sales@ensky-chemical.com | China | 88 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15956 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14336 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
View Lastest Price from Mosapride citrate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-09-20 | Mosapride citrate
112885-42-4
|
US $0.00-0.00 / kg | 1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | |
 |
2021-11-04 | Mosapride citrate
112885-42-4
|
US $10.00 / Kg/Bag | 1Kg/Bag | 99% | 20 Tons | Hebei Zhanyao Biotechnology Co. Ltd | |
 |
2021-09-29 | Mosapride citrate
112885-42-4
|
US $0.00 / KG | 1KG | 98.0% | 500kg/month | WUHAN FORTUNA CHEMICAL CO., LTD |
-
- Mosapride citrate
112885-42-4
- US $0.00-0.00 / kg
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- Mosapride citrate
112885-42-4
- US $10.00 / Kg/Bag
- 99%
- Hebei Zhanyao Biotechnology Co. Ltd
-
- Mosapride citrate
112885-42-4
- US $0.00 / KG
- 98.0%
- WUHAN FORTUNA CHEMICAL CO., LTD
112885-42-4(Mosapride citrate)Related Search:
Mosapride
Mosapride Impurity 3
Mosapride Impurity 6
Mosapride Impurity 7
4-amino-5-chloro-2-ethoxy-N-((2-morpholinyl)methyl)benzamide
Mosapride Impurity 8
Mosapride Impurity 2
Mosapride Citric Amide
Mosapride N-Oxide
Des-4-fluorobenzyl Mosapride-d5
1of4
4-AMINO-5-CHLORO-2-ETHOXY-N-[[4-(4-FLUOROBENZYL)-2-MORPHOLINYL]METHYL]BENZAMIDE CITRATE DIHYDRATE
4-Amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]-2-morpholinyl]methyl]-benzamide 2-hydroxy-1,2,3-propanetricarboxylate
Gasmotin
enzamidecitrate
yl)methyl)-,2-hydroxy-1,2,3-propanetricarboxylate(1:1)
4-Amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]-2-morpholinyl]methyl]benzamidecitrate
4-amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]morpholin-2-yl]methyl]benzamide
4-azanyl-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]morpholin-2-yl]methyl]benzamide
Benzamide, 4-amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]-2-morpholinyl]methyl]-, 2-hydroxy-1,2,3-propanetricarboxylate
4-amino-5-chloro-2-ethoxy-N-((4-(4-fluorobenzyl)morpholin-2-yl)methyl)benzamide 2-hydroxypropane-1,2,3-tricarboxylate
MOSAPRIDE CITRATE
(+-)-4-amino-5-chloro-2-ethoxy-n-((4-(4-fluorobenzyl)-2-morpholinyl)methyl)b
as4370
benzamide,4-amino-5-chloro-2-ethoxy-n-((4-((4-fluorophenyl)methyl)-2-morpholin
AS-4370 citrate
TAK-370 citrate
Mosapride citrate,>99%
Mosapride citrate USP/EP/BP
Mosapride Citrate
DISCONTINUED PLEASE SEE M730995
Mosapride Citrate (TAK-370
Mosapride CitrateQ: What is
Mosapride Citrate Q: What is the CAS Number of
Mosapride Citrate Q: What is the storage condition of
Mosapride Citrate Q: What are the applications of
Mosapride Citrate
Mosapridecitrate/TAK-370citrate/AS-4370citrate
112885-42-4
C21H25ClFN3O3C6H8O7C
C21H25ClFN3O3C6H8O72H20
C21H25ClFN3O3C6H8O72H2O
C21H25ClFN3O3C6H8O7
C21H25ClFN3O3C6H8O7C27H33ClFN3O10
C27H33ClFN3O10
Inhibitors
APIS
API
TAK-370, AS-4370, Gasmotin
Gastroprokinetic Agent