5,8,11-EICOSATRIYNOIC ACID
- CAS No.
- 13488-22-7
- Chemical Name:
- 5,8,11-EICOSATRIYNOIC ACID
- Synonyms
- ETI;EICOSATRIYNOIC ACID;5,8,11-Icosatriynoic acid;5,8,11-EICOSATRIYNOIC ACID;Icosa-5,8,11-triynoic acid;OWYNLPMPYBYKJP-UHFFFAOYSA-N;5,8,11-EICOSATRIYNOIC ACID Basic information;5,8,11-EICOSATRIYNOIC ACID ISO 9001：2015 REACH
- CBNumber:
- CB6705237
- Molecular Formula:
- C20H28O2
- Molecular Weight:
- 300.44
- MDL Number:
- MFCD00077343
- MOL File:
- 13488-22-7.mol
| Melting point | 70.5-71.5 °C |
|---|---|
| Boiling point | 473.8±40.0 °C(Predicted) |
| Density | 0.990±0.06 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 4.61±0.10(Predicted) |
| form | Off-white solid. |
| color | Pale Yellow to Pale Beige |
| Stability | Light Sensitive |
| FDA UNII | R7EU6LY7HJ |
5,8,11-EICOSATRIYNOIC ACID price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 90200 | 5,8,11-Eicosatriynoic Acid ≥99% | 13488-22-7 | 1mg | $85 | 2024-03-01 | Buy |
| Cayman Chemical | 90200 | 5,8,11-Eicosatriynoic Acid ≥99% | 13488-22-7 | 5mg | $359 | 2024-03-01 | Buy |
| Cayman Chemical | 90200 | 5,8,11-Eicosatriynoic Acid ≥99% | 13488-22-7 | 10mg | $633 | 2024-03-01 | Buy |
| TRC | E936910 | ETI | 13488-22-7 | 250mg | $1325 | 2021-12-16 | Buy |
| ApexBio Technology | C5811 | 5,8,11-EicosatriynoicAcid | 13488-22-7 | 10mg | $732 | 2021-12-16 | Buy |
5,8,11-EICOSATRIYNOIC ACID Chemical Properties,Uses,Production
Uses
ETI is a leukotriene antagonist and selective 5-LO (5-lipoxygenase) inhibitor.
Definition
ChEBI: A C20 polyunsaturated fatty acid having three triple bonds in the 5-, 8- and 11-positions.
Biological Activity
5,8,11-eicosatriynoic acid is a selective inhibitor of lipoxygenases with id50 values of 24 μm and 340 μm for n-8 lipoxygenase and fatty acid cycle-oxygenase , respectively[1][2].fatty acid cycle-oxygenase and n-8 lipoxygenase catalyze the initial reactions which lead to the formation of three major arachidonic acid metabolites in human platelets. in several tissues, these two enzymes act concomitantly on arachidonic acid [1].5,8,11-eicosatriynoic acid (5,8,11-et) is a selective inhibitor of lipoxygenases with id50 values of 24 μm and 340 μm for n-8 lipoxygenase and fatty acid cycle-oxygenase, respectively. 5,8,11-eicosatriynoic acid was useful for studies on physiological and pathophysiological roles of 12 l-hydroxy-5,8,10,14-eicosatetraenoic acid formation in various tissues [1]. in mouse mastocytoma cells, 5,8,11-eicosatriynoic acid inhibited a23187 and l-cysteine induced leukotriene c (ltc4) biosynthesis with id50 value of 5 μm [2].
References
[1]. hammarstrm s. selective inhibition of platelet n-8 lipoxygenase by 5,8,11-eicosatriynoic acid. biochim biophys acta. 1977 jun 22;487(3):517-9.
[2]. orning l, hammarstrm s. inhibition of leukotriene c and leukotriene d biosynthesis. j biol chem. 1980 sep 10;255(17):8023-6.
5,8,11-EICOSATRIYNOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
5,8,11-EICOSATRIYNOIC ACID Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2503 | 58 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9341 | 55 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| Hebei Binshare New Material Co. Ltd | +8618633865755 | china01@hbbinshare.com | CHINA | 969 | 58 |
| Shijiazhuang Erche Biotechnology Co., Ltd | 8613343119830 13343119830 | info07@byyq-cn.com | CHINA | 397 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 28098 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| Hebei Anda Technology Co., LTD | +86-19831998802 | 106@hebeianda.cn | China | 293 | 58 |
| Hebei Gongyuan New Material Technology Co., Ltd. | +8617331136198 | Grace@hebeisyjl.com | China | 497 | 58 |
View Lastest Price from 5,8,11-EICOSATRIYNOIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-07-25 | 5,8,11-EICOSATRIYNOIC ACID
13488-22-7
|
US $50.00 / kg | 1kg | 99.9% | 10000MT | Henan Bao Enluo International TradeCo.，LTD | |
 |
2023-05-04 | 5,8,11-EICOSATRIYNOIC ACID
13488-22-7
|
US $50.00 / KG | 1KG | 99% | 20 tons | Guangzhou Sunton Biotechnology Co., Ltd. | |
 |
2022-10-22 | ETI
13488-22-7
|
US $10.00 / kg | 1kg | 99% | Ex 20 tons | Hebei Anda Technology Co., LTD |
-
- 5,8,11-EICOSATRIYNOIC ACID
13488-22-7
- US $50.00 / kg
- 99.9%
- Henan Bao Enluo International TradeCo.，LTD
-
- 5,8,11-EICOSATRIYNOIC ACID
13488-22-7
- US $50.00 / KG
- 99%
- Guangzhou Sunton Biotechnology Co., Ltd.
-
- ETI
13488-22-7
- US $10.00 / kg
- 99%
- Hebei Anda Technology Co., LTD