ChemicalBook >> CAS DataBase List >>2-[(3,4-DICHLOROPHENYL)AMINO]-1,4-DIHYDRO-6-NITRO-4-OXO-N-2-PROPENYL-8-QUINAZOLINECARBOXAMIDE

2-[(3,4-DICHLOROPHENYL)AMINO]-1,4-DIHYDRO-6-NITRO-4-OXO-N-2-PROPENYL-8-QUINAZOLINECARBOXAMIDE

2-[(3,4-DICHLOROPHENYL)AMINO]-1,4-DIHYDRO-6-NITRO-4-OXO-N-2-PROPENYL-8-QUINAZOLINECARBOXAMIDE structure

CAS No.: 331645-84-2

Chemical Name:: 2-[(3,4-DICHLOROPHENYL)AMINO]-1,4-DIHYDRO-6-NITRO-4-OXO-N-2-PROPENYL-8-QUINAZOLINECARBOXAMIDE

Synonyms: AQZ-1;AZ 10417808;2-[(3,4-DICHLOROPHENYL)AMINO]-1,4-DIHYDRO-6-NITRO-4-OXO-N-2-PROPENYL-8-QUINAZOLINECARBOXAMIDE;8-Quinazolinecarboxamide, 2-[(3,4-dichlorophenyl)amino]-3,4-dihydro-6-nitro-4-oxo-N-2-propen-1-yl-

CBNumber:: CB6829694

Molecular Formula:: C18H13Cl2N5O4

Molecular Weight:: 434.23

MDL Number:: MFCD08703097

MOL File:: 331645-84-2.mol

Last updated:2023-05-18 11:31:05

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2-[(3,4-DICHLOROPHENYL)AMINO]-1,4-DIHYDRO-6-NITRO-4-OXO-N-2-PROPENYL-8-QUINAZOLINECARBOXAMIDE Properties

storage temp.	Store at RT
solubility	<10.86mg/ml in DMSO
form	solid
color	Yellow

2-[(3,4-DICHLOROPHENYL)AMINO]-1,4-DIHYDRO-6-NITRO-4-OXO-N-2-PROPENYL-8-QUINAZOLINECARBOXAMIDE price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	A808213	AZ10417808	331645-84-2	2.5mg	$250	2021-12-16	Buy
ApexBio Technology	A4416	AZ10417808	331645-84-2	5mg	$322	2021-12-16	Buy
American Custom Chemicals Corporation	HCH0351637	2-[(3,4-DICHLOROPHENYL)AMINO]-1,4-DIHYDRO-6-NITRO-4-OXO-N-2-PROPENYL-8-QUINAZOLINECARBOXAMIDE 95.00%	331645-84-2	5MG	$497.35	2021-12-16	Buy

Product number	Packaging	Price	Buy
A808213	2.5mg	$250	Buy
A4416	5mg	$322	Buy
HCH0351637	5MG	$497.35	Buy

2-[(3,4-DICHLOROPHENYL)AMINO]-1,4-DIHYDRO-6-NITRO-4-OXO-N-2-PROPENYL-8-QUINAZOLINECARBOXAMIDE Chemical Properties,Uses,Production

Uses

AZ 10417808 inhibits human caspase-3 with Ki values in the 90 to 800 nM range. AZ 10417808 blocks cellular and biochemical features of apoptosis in cells.

Definition

ChEBI: 2-(3,4-dichloroanilino)-6-nitro-4-oxo-N-prop-2-enyl-1H-quinazoline-8-carboxamide is a member of quinazolines.

Biological Activity

Selective non-peptide inhibitor of caspase-3 (K i = 247 nM); displays > 40-fold selectivity over caspases 1, 2, 6, 7 and 8 (K i > 10 μ M). Completely blocks staurosporine-induced intracellular DEVDase activity in SH-SY5Y cells (IC 50 = 14.9 μ M).

2-[(3,4-DICHLOROPHENYL)AMINO]-1,4-DIHYDRO-6-NITRO-4-OXO-N-2-PROPENYL-8-QUINAZOLINECARBOXAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

2-[(3,4-DICHLOROPHENYL)AMINO]-1,4-DIHYDRO-6-NITRO-4-OXO-N-2-PROPENYL-8-QUINAZOLINECARBOXAMIDE Suppliers

Global( 38)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14059	65
AdooQ BioScience, LLC	+1 (866) 930-6790	info@adooq.com	United States	2784	58
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60
Shanghai Han-Xiang Chemical Co., Ltd.	15971444841	amber@biochempartner.com	China	3063	58
Absin Bioscience Inc.	021-38015121 15000105423	chenjw@absin.cn	China	24734	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8141	58
Changzhou Furuisi Biotechnology Co., Ltd	0519-85524369	3477467573@qq.com	China	8618	58
ApexBio Technology	--	sales@apexbt.com	United States	6254	58

Supplier	Advantage
LEAPCHEM CO., LTD.	58
3B Pharmachem (Wuhan) International Co.,Ltd.	69
BOC Sciences	65
AdooQ BioScience, LLC	58
EMMX Biotechnology LLC	60
Shanghai Han-Xiang Chemical Co., Ltd.	58
Absin Bioscience Inc.	58
MedBioPharmaceutical Technology Inc	58
Changzhou Furuisi Biotechnology Co., Ltd	58
ApexBio Technology	58

331645-84-2(2-[(3,4-DICHLOROPHENYL)AMINO]-1,4-DIHYDRO-6-NITRO-4-OXO-N-2-PROPENYL-8-QUINAZOLINECARBOXAMIDE)Related Search:

N-O-TOLYL-GUANIDINE 6-NITROQUINAZOLIN-4(3H)-ONE N-(3,4-Dichlorophenyl)guanidine 3-(AMINOMETHYL)-N-METHYLBENZAMIDE HYDROCHLORIDE 2-[(3,4-DICHLOROPHENYL)AMINO]-1,4-DIHYDRO-6-NITRO-4-OXO-N-2-PROPENYL-8-QUINAZOLINECARBOXAMIDE

6-AMINO-3H-QUINAZOLIN-4-ONE 1,3-Diphenylguanidine

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2-[(3,4-DICHLOROPHENYL)AMINO]-1,4-DIHYDRO-6-NITRO-4-OXO-N-2-PROPENYL-8-QUINAZOLINECARBOXAMIDE AZ 10417808 AQZ-1 8-Quinazolinecarboxamide, 2-[(3,4-dichlorophenyl)amino]-3,4-dihydro-6-nitro-4-oxo-N-2-propen-1-yl- 331645-84-2 C18H13C12N5O4 C18H13Cl2N5O4