bupicomide
- CAS No.
- 22632-06-0
- Chemical Name:
- bupicomide
- Synonyms
- Sch-10595;bupicomide;Fusaramide;5-Butylpyridine-2-carboxamide;5-Butyl-2-pyridinecarboxamide;2-Pyridinecarboxamide, 5-butyl-;5-butyl-pyridine-2-carboxylic acid amide
- CBNumber:
- CB6878197
- Molecular Formula:
- C10H14N2O
- Molecular Weight:
- 178.234
- MDL Number:
- MFCD00865843
- MOL File:
- 22632-06-0.mol
| Melting point | 128 °C |
|---|---|
| Boiling point | 338.6±30.0 °C(Predicted) |
| Density | 1.066±0.06 g/cm3(Predicted) |
| pka | 15.28±0.50(Predicted) |
| FDA UNII | 0X3H76N0HY |
bupicomide price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B490838 | 5-butylpyridine-2-carboxamide | 22632-06-0 | 10mg | $65 | 2021-12-16 | Buy |
| TRC | B490838 | 5-butylpyridine-2-carboxamide | 22632-06-0 | 50mg | $240 | 2021-12-16 | Buy |
| TRC | B490838 | 5-butylpyridine-2-carboxamide | 22632-06-0 | 100mg | $350 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0996980 | 5-BUTYL-2-PYRIDINECARBOXAMIDE 95.00% | 22632-06-0 | 5MG | $501.28 | 2021-12-16 | Buy |
| AccelPharmtech | D6782 | 5-butyl-2-Pyridinecarboxamide 97.00% | 22632-06-0 | 25G | $13300 | 2021-12-16 | Buy |
bupicomide Chemical Properties,Uses,Production
Originator
Bupicomide,ZYF Pharm Chemical
Uses
Antihypertensive.
Definition
ChEBI: Bupicomide is an organothiophosphorus compound and a phosphoramide.
Manufacturing Process
3-n-Butyl-6-methyl-3,4-dihydro-1,2-pyran was obtained and isolated from the
reaction mixture by fractional distillation in vacuum to separate a by-product
formed by cyclodimerisation of methyl vinylketone. The yield of the3-n-butyl-
6-methyl-3,4-dihydro-1,2-pyran was 47% (boiling point 106-107°C.
The saponification of the 3-n-butyl-6-methyl-3,4-dihydro-1,2-pyran was
accomplished by heating for 0.5 h in a mixture with acetic acid. The 1-methyl-
4-n-butyl-1,5-dicarbonyl acid formed not isolated from the reaction mixture
was added to hydroxylamine. The reaction with hydroxylamine was carried out
by gradual addition of acetic acid solution of 1,5-dicarbonyl compound to the
stirring refluxing suspension of hydroxylamine in glacial acetic acid. By usual
treatment was fractionned in vacuum to yield 37.5% of 2-methyl-5-nbutylpyridine,
boiling point 105°C.
The 2-methyl-5-n-butylpyridine was oxidated by selenium dioxide in pyridine
to 5-n-butyl-2-pyridine carboxylic (fusarinic) acid, melting point 100-101°C.
25.0 g of the 5-n-butyl-2-pyridine carboxylic (fusarinic) acid and 25 ml of
thionyl chloride were mixed; after all of the acid is dissolved, concentrate (in
vacuo) the mixture and take up the mixture in 500 ml of anhydrous benzene;
with cooling add the mixture to a solution of excess ammonia in 1 l of
benzene, concentrate (in vacuo) the resulting mixture; add water and
potassium carbonate and extract the amide with ether; dry and concentrate
the ether extract and 5-n-butyl-2-pyridine carboxamide was obtained
(recrystallize from acetonitrile).
Therapeutic Function
Antihypertensive
bupicomide Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38631 | 58 | |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9806 | 58 |
| Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 | 3477467573@qq.com | China | 8617 | 58 |
| Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 17691182729 18161915376 | 1046@dideu.com | China | 9998 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24644 | 58 |
View Lastest Price from bupicomide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-12 | Bupicomide
22632-06-0
|
US $293.00-987.00 / mg | 99.76% | 10g | TargetMol Chemicals Inc. |
-
- Bupicomide
22632-06-0
- US $293.00-987.00 / mg
- 99.76%
- TargetMol Chemicals Inc.