LEUKOTRIENE B4
- CAS No.
- 71160-24-2
- Chemical Name:
- LEUKOTRIENE B4
- Synonyms
- LTB4;LEUKOTRIENE B4;Leukotriene B?;LTB4 (Leukotriene B4);VNYSSYRCGWBHLG-AMOLWHMGSA-N;Leukotriene B4 MaxSpecStandard;leukotriene B4 ethanol solution;Leukotriene B4 Lipid Maps MS Standard;Leukotriene B - CAS 71160-24-2 - Calbiochem;[5S,12R]-DIHYDROXY-[6Z,8E,10E,14Z]-EICOSATETRAENOIC ACID
- CBNumber:
- CB7159905
- Molecular Formula:
- C20H32O4
- Molecular Weight:
- 336.47
- MDL Number:
- MFCD00135630
- MOL File:
- 71160-24-2.mol
- MSDS File:
- SDS
| Boiling point | 536.4±50.0 °C(Predicted) |
|---|---|
| Density | 1.040±0.06 g/cm3(Predicted) |
| Flash point | 14 °C |
| storage temp. | -20°C |
| solubility | Soluble in ethanol (supplied pre-dissolved in anhydrous ethanol, 50μg/ml) |
| form | Clear oil |
| pka | 4.66±0.10(Predicted) |
| CAS DataBase Reference | 71160-24-2(CAS DataBase Reference) |
| FDA UNII | 1HGW4DR56D |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H319 | |||||||||
| Precautionary statements | P210-P233-P240-P241-P242-P305+P351+P338 | |||||||||
| Hazard Codes | F | |||||||||
| Risk Statements | 11 | |||||||||
| Safety Statements | 7-16 | |||||||||
| RIDADR | UN 1170 3/PG 2 | |||||||||
| WGK Germany | 1 | |||||||||
| NFPA 704 |
|
LEUKOTRIENE B4 price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | L0517 | Leukotriene B4 ~100?μg/mL in ethanol, ≥97% | 71160-24-2 | 10μg | $336 | 2024-03-01 | Buy |
| Sigma-Aldrich | L0517 | Leukotriene B4 ~100?μg/mL in ethanol, ≥97% | 71160-24-2 | 25μg | $531 | 2024-03-01 | Buy |
| Sigma-Aldrich | L0517 | Leukotriene B4 ~100?μg/mL in ethanol, ≥97% | 71160-24-2 | 50μg | $916 | 2024-03-01 | Buy |
| Sigma-Aldrich | 434625 | Leukotriene B₄ - CAS 71160-24-2 - Calbiochem | 71160-24-2 | 50μG | $503 | 2024-03-01 | Buy |
| Cayman Chemical | 20110 | Leukotriene B4 ≥97% | 71160-24-2 | 25μg | $144 | 2024-03-01 | Buy |
LEUKOTRIENE B4 Chemical Properties,Uses,Production
Description
Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-
LTB4 MaxSpec® standard is a quantitative grade standard of LTB4 that has been prepared specifically for mass spectrometry and related applications where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This LTB4 MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.
Uses
LTB4 (Leukotriene B4) is a potent chemokine with roles in inflammation, immunology, the nervous system, brain and skin.
Definition
ChEBI: A leukotriene composed of (6Z,8E,10E,14Z)-icosatetraenoic acid having (5S)- and (12R)-hydroxy substituents.
Biological Activity
Potent lipid inflammatory mediator derived from the 5-lipoxygenase pathway of arachidonic acid metabolism. Binds to BLT 1 and BLT 2 receptors and acts as a potent chemotactic agent and activator of leukocytes. Also displays antiviral activity towards DNA viruses and retroviruses.
Biochem/physiol Actions
Proinflammatory agent. Stimulates c-Fos and c-Jun proto-oncogene transcription in human monocytes. Stimulates chemotaxis, aggregation, and degranulation of polymorphonuclear leukocytes.
storage
Store at -20°C
LEUKOTRIENE B4 Preparation Products And Raw materials
Raw materials
Preparation Products
LEUKOTRIENE B4 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Mainchem Co., Ltd. | +86-0592-6210733 | sale@mainchem.com | China | 32360 | 55 |
| Shanghai Boyle Chemical Co., Ltd. | 021-50182298 021-50180596 | sales@boylechem.com | China | 2210 | 55 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 18521735133 18521732826; | market@aladdin-e.com | China | 25014 | 65 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
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