ASP 2151
- CAS No.
- 841301-32-4
- Chemical Name:
- ASP 2151
- Synonyms
- CS-2753;ASP 2151;Amcnamevir;AMenaMevir;Amenamevil;Amenamevir (ASP2151);ASP 2151 (Amenamevir);ASP2151;ASP 2151;ASP-2151;Rosuvastatin Impurity 184;Herpes simplex virus,Amenamevir,Inhibitor,ASP-2151,HSV,ASP 2151,inhibit
- CBNumber:
- CB72627341
- Molecular Formula:
- C24H26N4O5S
- Molecular Weight:
- 482.55
- MDL Number:
- MFCD19443709
- MOL File:
- 841301-32-4.mol
- MSDS File:
- SDS
Density | 1.360±0.06 g/cm3(Predicted) |
---|---|
storage temp. | Store at -20°C |
solubility |
DMF:PBS (pH 7.2) (1:20):0.04(Max Conc. mg/mL);0.08(Max Conc. mM) DMF:2.0(Max Conc. mg/mL);4.14(Max Conc. mM) |
form | A solid |
pka | 12.60±0.70(Predicted) |
FDA UNII | 94X46KW4AE |
ATC code | J05AX26 |
ASP 2151 price More Price(13)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 27921 | Amenamevir | 841301-32-4 | 1mg | $121 | 2024-03-01 | Buy |
Cayman Chemical | 27921 | Amenamevir | 841301-32-4 | 25mg | $1652 | 2024-03-01 | Buy |
Cayman Chemical | 27921 | Amenamevir | 841301-32-4 | 5mg | $452 | 2024-03-01 | Buy |
Cayman Chemical | 27921 | Amenamevir | 841301-32-4 | 10mg | $783 | 2024-03-01 | Buy |
TRC | A576425 | Amenamevir | 841301-32-4 | 50mg | $730 | 2021-12-16 | Buy |
ASP 2151 Chemical Properties,Uses,Production
Description
Amenamevir is an antiviral inhibitor of herpes simplex virus 1 (HSV-1) helicase-primase complex activity. It inhibits recombinant HSV-1 helicase with an IC50 value of 0.078 μM and recombinant HSV-1 primase when used at concentrations greater than or equal to 0.03 μM. Amenamevir inhibits replication of varicella-zoster virus (VZV), HSV-1, and HSV-2 in human embryonic fibroblast (HEF) cells (EC50s = 0.047, 0.036, and 0.028 μM, respectively) and is not cytotoxic to HEF cells with a 50% cytotoxic concentration (CC50) of greater than 30 μM. Amenamevir also inhibits replication of clinical VZV isolates in HEF cells (EC50s = 0.038-0.10 μM). In vivo, it increases survival of cutaneously HSV-1-infected mice in a zosteriform-spread model of progressive HSV-1 infection (ED50 = 1.9 mg/kg twice per day).
Uses
Amenamevir is a helicase-primase inhibitor which has potent antiviral activity against HSVs with an EC50 of 14 ng/mL.
ASP 2151 Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
Shenzhen Excellent Biotech Co., Ltd. | 13480692018 | ramyan@ex-biotech.com | CHINA | 954 | 58 |
career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd | +86-86-22-87899925 +86-8618522618860 | 18522618860@163.com | China | 694 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
View Lastest Price from ASP 2151 manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2021-04-16 | Amenamevir
841301-32-4
|
US $1.00 / KG | 1KG | 99% | 5000KG | Shenzhen Excellent Biotech Co., Ltd. | ||
2019-12-25 | ASP 2151
841301-32-4
|
US $1.00 / g | 1g | 99.99% | 200kg | Career Henan Chemical Co |
- Amenamevir
841301-32-4
- US $1.00 / KG
- 99%
- Shenzhen Excellent Biotech Co., Ltd.
- ASP 2151
841301-32-4
- US $1.00 / g
- 99.99%
- Career Henan Chemical Co