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ASP 2151

ASP 2151 Struktur
841301-32-4
CAS-Nr.
841301-32-4
Englisch Name:
ASP 2151
Synonyma:
CS-2753;ASP 2151;Amcnamevir;AMenaMevir;Amenamevil;Amenamevir (ASP2151);ASP 2151 (Amenamevir);ASP2151;ASP 2151;ASP-2151;Rosuvastatin Impurity 184;Herpes simplex virus,Amenamevir,Inhibitor,ASP-2151,HSV,ASP 2151,inhibit
CBNumber:
CB72627341
Summenformel:
C24H26N4O5S
Molgewicht:
482.55
MOL-Datei:
841301-32-4.mol
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ASP 2151 Eigenschaften

Dichte
1.360±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
Löslichkeit
DMF:PBS (pH 7.2) (1:20):0.04(Max Conc. mg/mL);0.08(Max Conc. mM)
DMF:2.0(Max Conc. mg/mL);4.14(Max Conc. mM)
Aggregatzustand
A solid
pka
12.60±0.70(Predicted)

Sicherheit

ASP 2151 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Amenamevir is an antiviral inhibitor of herpes simplex virus 1 (HSV-1) helicase-primase complex activity. It inhibits recombinant HSV-1 helicase with an IC50 value of 0.078 μM and recombinant HSV-1 primase when used at concentrations greater than or equal to 0.03 μM. Amenamevir inhibits replication of varicella-zoster virus (VZV), HSV-1, and HSV-2 in human embryonic fibroblast (HEF) cells (EC50s = 0.047, 0.036, and 0.028 μM, respectively) and is not cytotoxic to HEF cells with a 50% cytotoxic concentration (CC50) of greater than 30 μM. Amenamevir also inhibits replication of clinical VZV isolates in HEF cells (EC50s = 0.038-0.10 μM). In vivo, it increases survival of cutaneously HSV-1-infected mice in a zosteriform-spread model of progressive HSV-1 infection (ED50 = 1.9 mg/kg twice per day).

ASP 2151 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

ASP 2151 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 70)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32715 60
BOC Sciences 		+1-631-485-4226
inquiry@bocsci.com United States 19553 58
Shenzhen Excellent Biotech Co., Ltd. 		13480692018
ramyan@ex-biotech.com CHINA 954 58
career henan chemical co 		+86-0371-86658258 15093356674;
 factory@coreychem.com China 29826 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		+86-021-61551413 +8618813727289
 contact@trustwe.com China 5738 58
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd 		+86-86-22-87899925 +86-8618522618860
 18522618860@163.com China 694 58
InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6393 58
Nantong HI-FUTURE Biology Co., Ltd. 		+undefined18051384581
 sales@chemhifuture.com China 3136 58
TargetMol Chemicals Inc. 		+1-781-999-5354
support@targetmol.com United States 19973 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525
 masar@topule.com China 8474 58
  • ASP 2151
  • AMenaMevir
  • N-(2,6-Dimethylphenyl)tetrahydro-N-[2-[[4-(1,2,4-oxadiazol-3-yl)phenyl]amino]-2-oxoethyl]-2H-thiopyran-4-carboxamide 1,1-dioxide
  • ASP 2151 (Amenamevir)
  • CS-2753
  • ASP2151;ASP 2151;ASP-2151
  • N-(2,6-Dimethylphenyl)-N-(2-{[4-(1,2,4-oxadiazol-3-yl)phenyl] amino}-2-oxoethyl)-1,1-dioxothiane-4-carboxamide
  • N-(2-((4-(1,2,4-Oxadiazol-3-yl)phenyl)amino)-2-oxoethyl)-N-(2,6-dimethylphenyl)tetrahydro-2H-thiopyran-4-carboxamide 1,1-dioxide
  • Amenamevir (ASP2151)
  • 2H-Thiopyran-4-carboxamide, N-(2,6-dimethylphenyl)tetrahydro-N-[2-[[4-(1,2,4-oxadiazol-3-yl)phenyl]amino]-2-oxoethyl]-, 1,1-dioxide
  • Amcnamevir
  • Herpes simplex virus,Amenamevir,Inhibitor,ASP-2151,HSV,ASP 2151,inhibit
  • Amenamevil
  • Rosuvastatin Impurity 184
  • (2E)-3-[3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-2-Propenoic acid 1-methylethyl ester
  • 841301-32-4
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