ChemicalBook >> CAS DataBase List >>8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE
8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE
- CAS No.
- 102146-07-6
- Chemical Name:
- 8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE
- Synonyms
- DPCPX;1,3-Dpcpx;PD 116,948;8-CYCLOPENTYL-1;PD-116948(DPCPX);DPCPX, PD 116,948;3-DIPROPYLXANTHINE;Levodropropizine Impurity 15;cyclopentyl-1,3-dipropylxanthine;1,3-DIPROPYL-8-CYCLOPENTYLXANTHINE
- CBNumber:
- CB7472080
- Molecular Formula:
- C16H24N4O2
- Molecular Weight:
- 304.39
- MDL Number:
- MFCD00055117
- MOL File:
- 102146-07-6.mol
Last updated:2023-09-20 16:43:00
| Melting point | 178°C |
|---|---|
| Boiling point | 535.1±42.0 °C(Predicted) |
| Density | 1.195±0.06 g/cm3(Predicted) |
| storage temp. | Store at RT |
| solubility | DMSO: >10 mg/mL |
| pka | 9.01±0.70(Predicted) |
| form | solid |
| color | white |
| Stability | Store tightly sealed at RT; Solutions at 4 deg C for several days |
| CAS DataBase Reference | 102146-07-6(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 9PTP4FOI9E |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE price More Price(26)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C101 | 8-Cyclopentyl-1,3-dipropylxanthine solid | 102146-07-6 | 25mg | $91.6 | 2024-03-01 | Buy |
| Sigma-Aldrich | C101 | 8-Cyclopentyl-1,3-dipropylxanthine solid | 102146-07-6 | 100mg | $200 | 2024-03-01 | Buy |
| Tocris | 0439 | DPCPX ≥99%(HPLC) | 102146-07-6 | 100 | $195 | 2021-12-16 | Buy |
| TRC | C988500 | 8-Cyclopentyl-1,3-dipropylxanthine | 102146-07-6 | 50mg | $80 | 2021-12-16 | Buy |
| Usbiological | 255190 | DPCPX | 102146-07-6 | 100mg | $446 | 2021-12-16 | Buy |
8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
8-Cyclopentyl-1,3-dipropylxanthine has been used as an adenosine receptor (A1AR) antagonist in macrophages and human umbilical vein endothelial cells (HUVECs). It has also been used as A1AR antagonist in MCF-7 breast cancer cell line to test its anti-cancer effect.
Uses
DPCPX is a potent and very selective A1-adenosine receptor antagonist, with a Ki of 0.46 nM for A1 receptors in rat whole-brain membranes. Its 740-fold A1-selectivity is the highest reported for an adenosine antagonist
Definition
ChEBI: An oxopurine that is 7H-xanthine substituted at positions 1 and 3 by propyl groups and at position 8 by a cyclohexyl group.
Biological Activity
Potent and selective A 1 adenosine receptor antagonist, both in vitro and in vivo . K i values are 3.9, 130, 50 and 4000 nM for human A 1 , A 2A , A 2B and A 3 receptors respectively.
Biochem/physiol Actions
8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) is a selective A1?adenosine receptor antagonist. DPCPX possesses anti-cancer functionality. It induces apoptosis in breast cancer cells and favors mRNA expression of caspases.
storage
Room temperature
8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE Preparation Products And Raw materials
Raw materials
Preparation Products
8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE Suppliers
Global( 79)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33350 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| Mainchem Co., Ltd. | +86-0592-6210733 | sale@mainchem.com | China | 32360 | 55 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 6011 | 61 |
102146-07-6(8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE)Related Search:
N-PROPYLBENZENE
Cyclohexylbenzene
Trichloropropylsilane
8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE [DPCPX]
KFM 19
1of3
DPCPX, PD 116,948
8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE(DPCPX,1,3-DIPROPYL-8-CYCLOPENTYLXANTHINE)
cyclopentyl-1,3-dipropylxanthine
1,3-Dipropyl-8-cyclopentylxanthine, DPCPX, PD 116,948
1,3-Dipropyl-8-cyclopentyl-7H-purine-2,6(1H,3H)-dione
8-Cyclopentyl-3,7-dihydro-1,3-dipropyl-1H-purine-2,6-dione
1,3-Dpcpx
1H-Purine-2,6-dione, 8-cyclopentyl-3,7-dihydro-1,3-dipropyl-
8-Cyclopentyl-3,7-dihydro-1,3-dipropyl-1H-purin-2,6-dione
PD-116948(DPCPX)
8-cyclopentyl-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
8-Cyclopentyl-1,3-dipropyl-1H-purine-2,6(3H,7H)-dione
8-Cyclopentyl-3,9-dihydro-1,3-dipropyl-1H-purine-2,6-dione
PD 116,948
1,3-DIPROPYL-8-CYCLOPENTYLXANTHINE
8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE
DPCPX
8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE SELEC TIVE A1 ADENOSIN
8-CYCLOPENTYL-1
3-DIPROPYLXANTHINE
1H-Purine-2,6-dione, 8-cyclopentyl-3,9-dihydro-1,3-dipropyl-
P1 receptor,inhibit,Inhibitor,PD-116948,Adenosine Receptor,DPCPX,PD116948
8-Cyclopentyl-3,9-dihydro-1,3-dipropyl-1H-purin-2,6-dione
Levodropropizine Impurity 15
8-Cyclopentyl-1,3-dipropylxanthine solid
102146-07-6
C16H24N4O2
Adenosine receptor
All Inhibitors
Inhibitors
Heterocycles
Neurochemicals