Melitracen
- CAS No.
- 5118-29-6
- Chemical Name:
- Melitracen
- Synonyms
- N-7001;Dixeran;U-24973;Trausban;Melitrace;melitracen;Brn 1980107;MELITRACENE;Einecs 225-858-5;Melitracen USP/EP/BP
- CBNumber:
- CB7909593
- Molecular Formula:
- C21H25N
- Molecular Weight:
- 291.43
- MDL Number:
- MFCD00242904
- MOL File:
- 5118-29-6.mol
- MSDS File:
- SDS
Boiling point | 423.43°C (rough estimate) |
---|---|
Density | 0.9801 (rough estimate) |
refractive index | 1.4900 (estimate) |
pka | 9.18±0.28(Predicted) |
EWG's Food Scores | 1 |
FDA UNII | Q7T0Y1109Z |
ATC code | N06AA14 |
NIST Chemistry Reference | 1-Propanamine, 3-(10,10-dimethyl-9(10H)-anthracenylidene)-N,N-dimethyl-(5118-29-6) |
Melitracen price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
American Custom Chemicals Corporation | API0007908 | MELITRACEN 95.00% | 5118-29-6 | 5MG | $504.37 | 2021-12-16 | Buy |
AvaChem | 2810B | Melitracen | 5118-29-6 | 10mg | $95 | 2021-12-16 | Buy |
AvaChem | 2810B | Melitracen | 5118-29-6 | 100mg | $295 | 2021-12-16 | Buy |
Melitracen Chemical Properties,Uses,Production
Originator
Trausabun,Lusofarma,W. Germany,1965
Uses
Antidepressant.
Definition
ChEBI: Melitracen is a member of anthracenes.
Manufacturing Process
24 g of 2-o-benzoylphenylpropanol-2 (MP 116°C) were dissolved in 250 ml of anhydrous ether and the resulting solution was added dropwise while stirring to a suspension of 0.22 mol of dimethylaminopropylmagnesium chloride in 100 ml of ether. The reaction mixture was refluxed for one hour on a steam bath, and water and dilute hydrochloric acid were added until the reaction was pH 4-5. The aqueous phase was separated and 60 ml of concentrated aqueous ammonia were added. The mixture was extracted with ether, and the ether phase was separated, dried and evaporated in a steam bath. The residue was dissolved in hot petroleum ether and the solution left standing to cool for some time, whereupon 4-dimethylamino-1-phenyl-1-[2-(2-hydroxy-2- propyl)phenyl]-butanol-1 crystallized out as white crystals which were sucked off. After drying they melted at 88°C to 90°C.
10 g of this compound were cautiously dissolved in 50 ml of concentrated
sulfuric acid under cooling and the mixture was kept at room temperature for
24 hours, whereupon the reaction mixture was poured into 200 g of finely
crushed ice, and concentrated aqueous ammonia was added to about pH 9,
whereupon the oil which separated out was extracted with ether. The ether
phase was separated, dried and the ether evaporated on a steam bath. The
residue was dissolved in 20 ml of acetone and the solution neutralized with a
solution of dry hydrogen chloride in ether. The white crystals of 9-γdimethylaminopropylidene-10,10-dimethyl-9,10-dihydroanthracene
hydrochloride which separated out was filtered off and dried. Yield 9 g. MP
245°C to 247°C.
Therapeutic Function
Antidepressant
Melitracen Preparation Products And Raw materials
Raw materials
Preparation Products
Melitracen Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Nanjing Finetech Chemical Co., Ltd. | 025-85710122 17714198479 | sales@fine-chemtech.com | CHINA | 885 | 55 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 27644 | 58 |
GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 50000 | 58 |
Wuhan Han Sheng New Material Technology Co.,Ltd | +8617798174412 | admin01@hsnm.com.cn | China | 2118 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 19368 | 58 |
Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
View Lastest Price from Melitracen manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2021-07-27 | Melitracen USP/EP/BP
5118-29-6
|
US $1.10 / g | 1g | 99.9% | 100 Tons min | Dideu Industries Group Limited | ||
2019-12-20 | Melitracen
5118-29-6
|
US $1.00 / KG | 1KG | 99% | KG/T | Career Henan Chemical Co |
- Melitracen USP/EP/BP
5118-29-6
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited
- Melitracen
5118-29-6
- US $1.00 / KG
- 99%
- Career Henan Chemical Co