Flunoxaprofen

CAS No.
66934-18-7
Chemical Name:
Flunoxaprofen
Synonyms
Priaxim;Flunoxaprofen;S-(+)-Flunoxaprofen;Flunoxaprofen USP/EP/BP;(S)-2-(4-Fluorophenyl)-α-methyl-5-benzoxazoleacetic acid;5-Benzoxazoleacetic acid, 2-(4-fluorophenyl)-α-methyl-, (αS)-
CBNumber:
CB81178784
Molecular Formula:
C16H12FNO3
Molecular Weight:
285.273
MDL Number:
MFCD00870715
MOL File:
66934-18-7.mol
MSDS File:
SDS
Last updated:2023-07-14 17:40:53

Flunoxaprofen Properties

Melting point 162-164°
alpha D20 +50° (c = 2% in DMF)
Boiling point 419.4±30.0 °C(Predicted)
Density 1.334±0.06 g/cm3(Predicted)
pka 4.36±0.30(Predicted)
FDA UNII UKU5U19W9M
ATC code G02CC04,M01AE15

SAFETY

Risk and Safety Statements

Toxicity LD50 orally in mice: ~1200 mg/kg (Dunwell)

Flunoxaprofen Chemical Properties,Uses,Production

Description

Flunoxaprofen is an antiinflammatory related to now withdrawn benoxaprofen, reportedly useful in the treatment of rheumatoid arthritis, myositis, synovitis and osteoarthritis. Its major mechanism of action is reported to be lipoxygenase inhibition, thus enabling the control of inflammation with less severe gastric disturbances.

Originator

Ravizza (Italy)

Definition

ChEBI: A monocarboxylic acid that is propionic acid substituted at position 2 by a 2-(4-chlorophenyl)-1,3-benzoxazol-5-yl group (the S-enantiomer). Although it was shown to be effective in treatment of rheumatoid arthritis and osteoarthritis, the clinical use of flunoxaprofen was discontinued due to possible hepatotoxic side-effects.

brand name

Priaxim

Flunoxaprofen Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 2)Suppliers
Supplier Tel Email Country ProdList Advantage
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 27690 58
Supplier Advantage
Dideu Industries Group Limited
58

View Lastest Price from Flunoxaprofen manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Flunoxaprofen USP/EP/BP pictures 2021-06-10 Flunoxaprofen USP/EP/BP
66934-18-7
US $1.10 / g 1g 99.9% 100 Tons Min Dideu Industries Group Limited
Flunoxaprofen (S)-2-(4-Fluorophenyl)-α-methyl-5-benzoxazoleacetic acid Priaxim S-(+)-Flunoxaprofen Flunoxaprofen USP/EP/BP 5-Benzoxazoleacetic acid, 2-(4-fluorophenyl)-α-methyl-, (αS)- 66934-18-7