3-(2,2,2-Trimethylhydrazine)methylpropionate bromide
- CAS No.
- 106966-25-0
- Chemical Name:
- 3-(2,2,2-Trimethylhydrazine)methylpropionate bromide
- Synonyms
- Meldonium impurity C CRS;3-(2,2,2-Trimethylhydrazinyl)Methyl Propionate Bromide (Thmp);2-(3-Methoxy-3-oxopropyl)-1,1,1-trimethylhydrazin-1-ium Bromide;3-(2,2,2-Trimethylhydrazinyl)-propanoic acid methyl ester bromide;PROPANOIC ACID, 3-(2,2,2-TRIMETHYLHYDRAZINYL)-, METHYL ESTER BROMIDE;Hydrazinium, 2-(3-methoxy-3-oxopropyl)-1,1,1-trimethyl-, bromide (1:1)
- CBNumber:
- CB82464705
- Molecular Formula:
- C7H17N2O2.Br
- Molecular Weight:
- 241.127
- MDL Number:
- MFCD10465251
- MOL File:
- 106966-25-0.mol
- MSDS File:
- SDS
| Density | 1.38 at 20℃ |
|---|---|
| vapor pressure | 5hPa at 20-25℃ |
| LogP | -3.26 at 24℃ and pH6.2 |
| FDA UNII | 7U369DR9PL |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H412 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P273-P501 |
3-(2,2,2-Trimethylhydrazine)methylpropionate bromide price More Price(1)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | CHM0377436 | 3-(2,2,2-TRIMETHYLHYDRAZINYL)-PROPANOIC ACID METHYL ESTER BROMIDE 95.00% | 106966-25-0 | 5MG | $499.25 | 2021-12-16 | Buy |
| Product number | Packaging | Price | Buy |
|---|---|---|---|
| CHM0377436 | 5MG | $499.25 | Buy |
3-(2,2,2-Trimethylhydrazine)methylpropionate bromide Chemical Properties,Uses,Production
Uses
3-(2,2,2-Trimethylhydrazine)methylpropionate bromide can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.
Synthesis
In a three-necked round bottom flask equipped with a mechanical stirrer, a dropping funnel and a reflux condenser, 172 g (2 mol) of methyl acrylate was added, and under cooling, 132 g (2.2 mol) of 1,1-dimethylhydrazine was added dropwise. After a period of 2 hours, the reaction mixture was heated at the same temperature until methyl 3-(2,2-dimethylhydrazo)propionate was formed (monitored by GM-MS). The above methyl 3-(2,2-dimethylhydrazinyl)propanoate product was dissolved in 40% ethanol (350 ml), cooled to 0 ° C, and methyl bromide (189 g, 1.99 mol) was passed for 1 hour, and the temperature was continued. After stirring for 0, 5 hours, the yellow or brown precipitate was filtered off, and the crude product was washed with acetone (1000 ml). The crude 3-(2,2,2-trimethylhydrazine) propionate methyl bromide was dried (265.7 g, yield 91.0%); the crude product was recrystallized from ethanol and dried to give 219.8 g of pale yellow crystalline powder. The rate is 75.3%, the melting point is 130-132°C, and the main content is 103.3%. (The stability is verified by the stability test. The stability is poor, the color gradually becomes deeper. Because the trace impurities contained in the product have a great influence on the product, it is found to have molecular decay and various indicators. Larger, the product is valid for up to two years).
3-(2,2,2-Trimethylhydrazine)methylpropionate bromide Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15954 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52861 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25363 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178 +86-85511178 | peter68@ptchemgroup.com | China | 35453 | 58 |
| ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 | admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com | China | 19949 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 50000 | 58 |
| Mainchem Co., Ltd. | -- | sarah@mainchem.com | China | 6572 | 58 |
| XiaoGan ShenYuan ChemPharm co,ltd | 15527768850 | 1791901229@qq.com | China | 8849 | 52 |
| Chengdu HuaXia Chemical Reagent Co. Ltd | 400-1166-196 13458535857 | cdhxsj@163.com | China | 13359 | 58 |