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13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2

CAS No.
363-23-5
Chemical Name:
13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2
Synonyms
PGEM;13,14-Dihydro-15-keto-PGE2;CUJMXIQZWPZMNQ-XYYGWQPLSA-N;15-keto-13,14-dihydroprostaglandine2;13,14-dihydro-15-oxo-prostaglandin E2;13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2;13,14-Dihydro-15-ketoprostaglandinE2 solution;9,15-DIOXO-11ALPHA-HYDROXY-PROST-5Z-EN-1-OIC ACID;(5Z)-11α-Hydroxy-9,15-dioxoprosta-5-ene-1-oic acid;(5Z,11α)-11-Hydroxy-9,15-dioxoprost-5-en-1-oic acid
CBNumber:
CB8349316
Molecular Formula:
C20H32O5
Molecular Weight:
352.47
MDL Number:
MFCD00135217
MOL File:
363-23-5.mol
Last updated:2023-06-08 09:01:56

13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2 Properties

Boiling point 538.1±45.0 °C(Predicted)
Density 1.086±0.06 g/cm3(Predicted)
storage temp. −20°C
pka 4.75±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08
Signal word  Warning
Hazard statements  H302-H312-H315-H319-H332-H335-H351
Precautionary statements  P261-P280-P305+P351+P338
Hazard Codes  F,Xn,Xi
Risk Statements  11-20/21/22-36/37/38-67-66-36
Safety Statements  16-26-36
RIDADR  UN 1231 3/PG 2
WGK Germany  3
NFPA 704
3
2 0

13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2 price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 14650 13,14-dihydro-15-keto Prostaglandin E2 ≥95% 363-23-5 1mg $77 2024-03-01 Buy
Cayman Chemical 14650 13,14-dihydro-15-keto Prostaglandin E2 ≥95% 363-23-5 5mg $340 2024-03-01 Buy
Cayman Chemical 14650 13,14-dihydro-15-keto Prostaglandin E2 ≥95% 363-23-5 10mg $602 2024-03-01 Buy
Cayman Chemical 10007214 13,14-dihydro-15-keto Prostaglandin E2 MaxSpec? Standard >95% 363-23-5 100μg $118 2023-06-20 Buy
Product number Packaging Price Buy
14650 1mg $77 Buy
14650 5mg $340 Buy
14650 10mg $602 Buy
10007214 100μg $118 Buy

13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2 Chemical Properties,Uses,Production

Description

13,14-dihydro-15-keto Prostaglandin E2 (13,14-dihydro-15-keto PGE2) is a metabolite of PGE2 and the primary PGE2 metabolite in plasma. It is formed from PGE2 via a 15-keto PGE2 intermediate by 15-oxo-PG Δ13 reductase. Unlike PGE2, 13,14-dihydro-15-keto PGE2 does not bind effectively to the PGE2 receptors EP2 and EP4 expressed in CHO cells (Kis = 12 and 57 μM, respectively) or induce adenylate cyclase activity in the same cells (EC50s = >18 and >38 μM, respectively). Levels of 13,14-dihydro-15-keto PGE2 are increased in the plasma of women in the third trimester of pregnancy and in women during and immediately after labor and delivery. Levels of 13,14-dihydro-15-keto PGE2 levels are decreased in tumor tissue compared to adjacent non-cancerous tissue isolated from patients with non-small cell lung cancer (NSCLC).

Uses

13,14-Dihydro-15-ketoPGE2 is a primary metabolite of PGE2 in plasma.

Definition

ChEBI: The 13,14-dihydro derivative of 15-oxo-prostaglandin E2.

13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2 Preparation Products And Raw materials

Raw materials

Preparation Products

13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2 Suppliers

Global( 21)Suppliers
Supplier Tel Email Country ProdList Advantage
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525 masar@topule.com China 8474 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd 0571-85361029 synstar518@163.com China 1991 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Hubei Kele Fine Chemical Co., Ltd 027-59101668 19945030958 2881924765@qq.com China 7973 58
amyjetsci 027-59626688 18771149750 sales@amyjet.com China 3004 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. +86-18521732826 market@aladdin-e.com China 48467 58
9,15-DIOXO-11ALPHA-HYDROXY-PROST-5Z-EN-1-OIC ACID 15-keto-13,14-dihydroprostaglandine2 13,14-dihydro-15-oxo-prostaglandin E2 13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2 (E)-7-[(1R,2R,3R)-3-hydroxy-5-oxo-2-(3-oxooctyl)cyclopentyl]hept-5-enoic acid 13,14-Dihydro-15-keto-PGE2 13,14-Dihydro-15-ketoprostaglandinE2 solution (5Z)-11α-Hydroxy-9,15-dioxoprosta-5-ene-1-oic acid (5Z,11α)-11-Hydroxy-9,15-dioxoprost-5-en-1-oic acid PGEM 13,14-dihydro-15-keto Prostaglandin E2 Lipid Maps MS Standard CUJMXIQZWPZMNQ-XYYGWQPLSA-N 13,14-dihydro-15-keto Prostaglandin E2 MaxSpecStandard Prost-5-en-1-oic acid, 11-hydroxy-9,15-dioxo-, (5Z,11α)- 363-23-5