ChemicalBook >> CAS DataBase List >>PAGOCLONE
PAGOCLONE
- CAS No.
- 133737-32-3
- Chemical Name:
- PAGOCLONE
- Synonyms
- Ip 456;CI-1043;RP 59037;AGOCLONE;Rp 62955;(+)-Pagoclone;(+)-RP-59037; IP-456; RP-62955; CI-1043;2-(7-Chloro-1,8-naphthyridin-2-yl)-3-(5-Methyl-2-oxohexyl)isoindolin-1-one;2-(7-Chloro-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxohexyl)-1-isoindolinone;inhibit,GABA Receptor,γ-Aminobutyric acid Receptor,Gamma-aminobutyric acid Receptor,IP 456,RP 62955,RP62955,Pagoclone,Inhibitor
- CBNumber:
- CB8839954
- Molecular Formula:
- C23H22ClN3O2
- Molecular Weight:
- 407.89
- MDL Number:
- MFCD00864700
- MOL File:
- 133737-32-3.mol
Last updated:2024-04-07 11:37:32
| Boiling point | 582.1±50.0 °C(Predicted) |
|---|---|
| Density | 1.273±0.06 g/cm3(Predicted) |
| pka | 1.62±0.30(Predicted) |
| InChI | InChI=1S/C23H22ClN3O2/c1-14(2)7-10-16(28)13-19-17-5-3-4-6-18(17)23(29)27(19)21-12-9-15-8-11-20(24)25-22(15)26-21/h3-6,8-9,11-12,14,19H,7,10,13H2,1-2H3 |
| InChIKey | HIUPRQPBWVEQJJ-UHFFFAOYSA-N |
| SMILES | C1(=O)C2=C(C=CC=C2)C(CC(=O)CCC(C)C)N1C1=CC=C2C(=N1)N=C(Cl)C=C2 |
| FDA UNII | 38VAG2SA33 |
PAGOCLONE price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth Carbosynth | BP177437 | Pagoclone NEW | 133737-32-3 | 25mg | $198.75 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BP177437 | Pagoclone NEW | 133737-32-3 | 50mg | $265 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BP177437 | Pagoclone NEW | 133737-32-3 | 100mg | $360 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BP177437 | Pagoclone NEW | 133737-32-3 | 250mg | $475 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BP177437 | Pagoclone NEW | 133737-32-3 | 500mg | $650 | 2021-12-16 | Buy |
PAGOCLONE Chemical Properties,Uses,Production
Description
Pagoclone is a drug that belongs to the class of cyclopyrrolones. It binds to the benzodiazepine binding site on GABAA receptors and acts as a negative allosteric modulator, thereby enhancing the inhibitory effects of GABA and reducing neuronal excitability.
Uses
Anti-anxiety agent.
Application
Pagoclone has been shown to have anti-inflammatory properties in an animal model of inflammatory bowel disease and may be useful for the treatment of this condition.
brand name
Bextra (Interneuron).
PAGOCLONE Preparation Products And Raw materials
Raw materials
Preparation Products
PAGOCLONE Suppliers
Global( 51)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Xi'an MC Biotech, Co., Ltd. | 029-89275612 +8618991951683 | mcbio_sales@163.com | China | 2255 | 58 |
| airuikechemical co., ltd. | +undefined86-15315557071 | sales05@airuikechemical.com | China | 994 | 58 |
| Dorne Chemical Technology co. LTD | +86-13583358881 +86-18560316533 | Ethan@dornechem.com | China | 296 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Hebei Runbin Biotechnology Co. LTD | 13180553332 | 2179877681@qq.com | CHINA | 996 | 58 |
| Wuhan Monad Medicine Tech Co.,LTD | 02768782018 18771942761 | sales01@whmonad.com | CHINA | 992 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 6709 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| Shanghai Biolang Biotechnology Co., Ltd. | +86-15970428662 +86-13397199602 | Niky@biolang.cn | China | 518 | 58 |
View Lastest Price from PAGOCLONE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-05-22 | Pagoclone
133737-32-3
|
US $1.00 / g | 1g | 99% | 100kg | Dorne Chemical Technology co. LTD | |
 |
2024-04-12 | PAGOCLONE
133737-32-3
|
US $0.00 / kg | 1kg | 0.99 | 10T | Shandong Hanjiang Chemical Co., Ltd | |
 |
2024-04-07 | PAGOCLONE
133737-32-3
|
US $0.00-0.00 / Kg | 1Kg | 99.9% | 20 tons | airuikechemical co., ltd. |
133737-32-3(PAGOCLONE)Related Search:
2-(7-Chloro-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxohexyl)-1-isoindolinone
RP 59037
Ip 456
Rp 62955
2-(7-Chloro-1,8-naphthyridin-2-yl)-3-(5-Methyl-2-oxohexyl)isoindolin-1-one
(+)-RP-59037; IP-456; RP-62955; CI-1043
CI-1043
AGOCLONE
inhibit,GABA Receptor,γ-Aminobutyric acid Receptor,Gamma-aminobutyric acid Receptor,IP 456,RP 62955,RP62955,Pagoclone,Inhibitor
(+)-Pagoclone
133737-32-3
C23H22ClN3O2