Bunazosin hydrochloride
- CAS No.
- 52712-76-2
- Chemical Name:
- Bunazosin hydrochloride
- Synonyms
- E-643;E 1015;E-1015;Detantol;Detantol-R;Bunazosin Hcl;Bunzaosin Hcl;Bunazosin, DETANTO;BUNAZOSIN HYDROCHLORIDE;Bunazosin hydrochloride USP/EP/BP
- CBNumber:
- CB9189463
- Molecular Formula:
- C19H28ClN5O3
- Molecular Weight:
- 409.91
- MDL Number:
- MFCD00941411
- MOL File:
- 52712-76-2.mol
| Melting point | 280-282° |
|---|---|
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly, Heated), Methanol (Slightly, Heated) |
| form | Solid |
| color | White to Off-White |
| Stability | Hygroscopic |
| FDA UNII | 18V54TZ7U6 |
Bunazosin hydrochloride price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B689585 | BunazosinHydrochloride | 52712-76-2 | 10mg | $65 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0002269 | BUNAZOSIN HYDROCHLORIDE 95.00% | 52712-76-2 | 100MG | $1370.41 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0002269 | BUNAZOSIN HYDROCHLORIDE 95.00% | 52712-76-2 | 1G | $2355.15 | 2021-12-16 | Buy |
| Chemenu | CM193842 | BunazosinHydrochloride 95% | 52712-76-2 | 1g | $1117 | 2021-12-16 | Buy |
| Crysdot | CD31001617 | BunazosinHydrochloride 95+% | 52712-76-2 | 1g | $1186 | 2021-12-16 | Buy |
Bunazosin hydrochloride Chemical Properties,Uses,Production
Description
Bunazosin hydrochloride is a selective αl-adrenergic antagonist related to prazosin and useful in the treatment of hypertension.
Originator
Eisai (Japan)
Uses
Bunazosin Hydrochloride is an α-1 adrenergic receptor antagonist that acts as an anti-cancer and anti-glaucoma drug.
Definition
ChEBI: Bunazosin hydrochloride is a member of quinazolines.
Manufacturing Process
17.0 g of 2-chloro-4-amino-6,7-dimethoxyquinazoline and 18.2 g of Nformylhomopiperazine
are added to 170 ml of butanol and the whole is
refluxed with stirring for 3 h. After completion of the reaction, the mixture is
cooled, and the crystals thus precipitated are filtered out, washed with a small
quantity of ethanol and air-dried. 25.0 g of crude 2-homopiperazino-4-amino-
6,7-dimethoxyquinazoline are obtained.
A solution of 2-homopiperazino-4-amino-6,7-dimethoxyquinazoline in 60 ml of
acetone is added dropwise to a solution of 2-butylcarboxylic acid chloride in
acetone under stirring and ice-cooling. After completion of the addition, the
stirring is continued for additional 1 h to complete the reaction. The crystals
thus precipitated are filtered out and the 1-(4-amino-6,7-dimethoxy-2-
quinazolinyl)hexahydro-4-(1-oxobutyl)-1H-1,4-diazepine, melting point 280-
282°C (recrystallized from a mixture of methanol-ethanol) is obtained.
brand name
DETANTOL
Therapeutic Function
Antihypertensive
Bunazosin hydrochloride Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23556 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9126 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 28659 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 50000 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10269 | 58 |
| Wuhan DKY Technology Co.,Ltd. | 27-81302488 18007166089 | info@dkybpc.com | China | 2024 | 58 |
View Lastest Price from Bunazosin hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-08-11 | Bunazosin hydrochloride USP/EP/BP
52712-76-2
|
US $1.10 / g | 1g | 99.9% | 100 Tons min | Dideu Industries Group Limited | |
 |
2020-05-10 | Bunazosin hydrochloride
52712-76-2
|
US $0.00-0.00 / Kg | 1KG | 99.0% | 500 MT | Shaanxi Dideu Medichem Co. Ltd |
-
- Bunazosin hydrochloride USP/EP/BP
52712-76-2
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited
-
- Bunazosin hydrochloride
52712-76-2
- US $0.00-0.00 / Kg
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd