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Pranoprofen

Pranoprofen structure

CAS No.: 52549-17-4

Chemical Name:: Pranoprofen

Synonyms: 2-(5H-Chromeno[2,3-b]pyridin-7-yl)propanoic acid;Niflan;Y 8004;Cesflan;Oftalar;ranoprofen;PRANOPROFEN;pyranoprofen;dl-Pranoprofen;(RS)-Pranoprofen

CBNumber:: CB9189564

Molecular Formula:: C15H13NO3

Molecular Weight:: 255.27

MDL Number:: MFCD00866111

MOL File:: 52549-17-4.mol

MSDS File:: SDS

Last updated:2024-04-25 13:42:50

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Pranoprofen Properties

Melting point	182-183°
Boiling point	398.5°C (rough estimate)
Density	1.1654 (rough estimate)
refractive index	1.5500 (estimate)
storage temp.	2-8°C
solubility	DMSO (Slightly), Methanol (Slightly)
pka	4.27±0.10(Predicted)
form	powder
color	white to beige
CAS DataBase Reference	52549-17-4(CAS DataBase Reference)
FDA UNII	2R7O1ET613
ATC code	S01BC09

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS06

Signal word

Danger

Hazard statements

H301

Precautionary statements

P301+P310+P330

RIDADR

UN 2811 6.1 / PGIII

RTECS

DJ3100950

Toxicity

LD50 in male mice, rats (mg/kg): 447.3, 87.3 orally (Edanaga)

NFPA 704

	0
2		0

Pranoprofen price More Price(35)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	SML1423	Pranoprofen ≥98% (HPLC)	52549-17-4	50mg	$38.9	2024-03-01	Buy
Sigma-Aldrich	SML1423	Pranoprofen ≥98% (HPLC)	52549-17-4	250mg	$115	2024-03-01	Buy
Cayman Chemical	17875	Pranoprofen ≥98%	52549-17-4	50mg	$32	2024-03-01	Buy
Cayman Chemical	17875	Pranoprofen ≥98%	52549-17-4	1g	$359	2024-03-01	Buy
Cayman Chemical	17875	Pranoprofen ≥98%	52549-17-4	100mg	$61	2024-03-01	Buy

Product number	Packaging	Price	Buy
SML1423	50mg	$38.9	Buy
SML1423	250mg	$115	Buy
17875	50mg	$32	Buy
17875	1g	$359	Buy
17875	100mg	$61	Buy

Pranoprofen Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Originator

Niflan, Yoshitomi ,Japan ,1981

Uses

Pranoprofen is an anti-inflammatory used in ophthalmology.

Definition

ChEBI: Pranoprofen is a pyridochromene.

Manufacturing Process

A mixture of 100 g of ethyl 2-cyano-2-(5H-[1]benzopyrano[2,3-b]-pyridin-7yl)propionate, 500 ml of glacial acetic acid and 200 g of concentrated hydrochloric acid is refluxed for 48 hours. The reaction mixture is concentrated, and the residue is dissolved in hot water. The solution is adjusted to pH 2 to 3 by addition of 10% sodium hydroxide. The resulting crystalline precipitate is washed thoroughly with water, and recrystallized from aqueous dioxane to give 74 g of 2-(5H-[1]benzopyrano[2,3-b]-pyridin-7yl)propionic acid as white crystals melting at 183°C to 183.5°C.

Therapeutic Function

Analgesic, Antiinflammatory

General Description

Pranoprofen is an arylalkanoic acid and a non-steroidal anti-inflammatory drug.

Biochem/physiol Actions

Pranoprofen is used in eyes to treat chronic allergic conjunctivitis. It is also used as an anti-inflammatory and analgesic drug after strabismus surgery.

Pranoprofen Preparation Products And Raw materials

Raw materials

Hydrochloric acid

Preparation Products

Pranoprofen Suppliers

Global( 289)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12467	58
airuikechemical co., ltd.	+undefined86-15315557071	sales05@airuikechemical.com	China	994	58
Ouhuang Engineering Materials (Hubei) Co., Ltd	+8617702722807	admin@hbouhuang.com	China	3001	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21689	55
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3620	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Hebei Guanlang Biotechnology Co., Ltd.	+86-19930503282	alice@crovellbio.com	China	8822	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58

Supplier	Advantage
Hebei Mojin Biotechnology Co., Ltd	58
airuikechemical co., ltd.	58
Ouhuang Engineering Materials (Hubei) Co., Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Shanghai Zheyan Biotech Co., Ltd.	58
career henan chemical co	58
Hubei Jusheng Technology Co.,Ltd.	58
Hebei Guanlang Biotechnology Co., Ltd.	58
BOC Sciences	58
Chongqing Chemdad Co., Ltd	58

View Lastest Price from Pranoprofen manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-25	Pranoprofen 52549-17-4	US $15.00 / kg	1kg	99.912%	10ton	Ouhuang Engineering Materials (Hubei) Co., Ltd
2024-04-10	Pranoprofen 52549-17-4	US $0.00-0.00 / mg	10mg	90%+	10g	Guangzhou PI PI BIOTECH INC
2024-04-07	Pranoprofen 52549-17-4	US $0.00-0.00 / g	1g	99.9%	20 tons	airuikechemical co., ltd.

Pranoprofen
52549-17-4
US $15.00 / kg
99.912%
Ouhuang Engineering Materials (Hubei) Co., Ltd

Pranoprofen
52549-17-4
US $0.00-0.00 / mg
90%+
Guangzhou PI PI BIOTECH INC

Pranoprofen
52549-17-4
US $0.00-0.00 / g
99.9%
airuikechemical co., ltd.

Pranoprofen Spectrum

Pranoprofen(52549-17-4)¹HNMR

52549-17-4(Pranoprofen)Related Search:

Centchroman Imidocarb dipropionate Folic acid Propionic acid Nandrolone phenylpropionate

3-(4-Hydroxyphenyl)propionic acid Ethyl 2-(Chlorosulfonyl)acetate 3-Phenylpropionic acid Ascoric Acid Ibuprofen

N,N-dimethylcarbamoylmethyl alpha,2-dimethyl-5H-1-benzopyrano(2,3-b)pyridine-7-acetate ALFA-METHYL-5H-[1] BENZOPYRANO [2,3-B] PYRIDINE-7-ACETIC ACID ETHYL ESTER 4-METHOXY-3-METHYLPHENYLACETIC ACID Pranoprofen l-Pranoprofen,(S)-(+)-Pranoprofen

(R)-Pranoprofen,(R)-(-)-Pranoprofen,d-Pranoprofen 2-(4-METHOXY-3-METHYLPHENYL)ACETALDEHYDE ALFA-METHYL-ALFA-CYANO-5H-[1] BENZOPYRANO [2,3-B] PYRIDINE-7-ACETIC ACID ETHYL ESTER

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PRANOPROFEN (RS)-Pranoprofen 5H-[1]Benzopyrano[2,3-b]pyridine-7-acetic acid, a-methyl- (9CI) a-Methyl-5H-[1]benzopyrano[2,3-b]pyridine-7-ylacetic acid dl-Pranoprofen Y 8004 pyranoprofen (S)-2-[5H-[1]Benzopyrano[2,3-b]pyridin-7-yl]propionic acid [S,(+)]-2-[5H-[1]Benzopyrano[2,3-b]pyridin-7-yl]propionic acid (R)-2-[5H-[1]Benzopyrano[2,3-b]pyridin-7-yl]propionic acid [R,(-)]-2-[5H-[1]Benzopyrano[2,3-b]pyridin-7-yl]propionic acid Cesflan α-Methyl-5H-[1]benzopyrano[2,3-b]pyridine-7-acetic acid 2-(5h-[1]benzopyrano[2,3-b]pyridin-7-yl)propionic acid Oftalar Pranoprofen, >=99% 5H-[1]Benzopyrano[2,3-b]pyridine-7-aceticacid, a-methyl- Pranoprofen-13C-d3 Pranoprofen（mixture of isomers） 5H-[1]Benzopyrano[2,3-b]pyridine-7-acetic acid, α-methyl- (2S)-2-(5H-chromeno[2,3-b]pyridin-7-yl)propanoic acid Pranoprofen USP/EP/BP Pranoprofen (Pyranoprofen) Antipyretic analgesics Pranoprofen Niflan 2-(5H-Chromeno[2,3-b]pyridin-7-yl)propanoic acid ranoprofen 52549-17-4 NIFLAN Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals >97%,BR 52549-17-4