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Taurodeoxycholic acid sodium salt

CAS No.
1180-95-6
Chemical Name:
Taurodeoxycholic acid sodium salt
Synonyms
SODIUM TAURODEOXYCHOLATE;Taurodeoxycholate sodium salt;Taurodeoxycholic acid sodium salt hydrate;5B2;12B1;sodium 2-[[(3B1;sodium taurodeoxylate;SodiuM taurodeoxycholat;Sodium deoxytaurocholate;Taurodeoxycholate sodium
CBNumber:
CB9349065
Molecular Formula:
C26H44NNaO6S
Molecular Weight:
521.69
MDL Number:
MFCD00003671
MOL File:
1180-95-6.mol
Last updated:2023-10-16 16:12:12

Taurodeoxycholic acid sodium salt Properties

Melting point 168 °C (dec.)(lit.)
alpha 33 º (c=3, water)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility H2O: 0.5 M at 20 °C, clear, colorless to faintly yellow
form Solid
color White to Off-White
Water Solubility soluble
InChIKey YXHRQQJFKOHLAP-UROAIUCXNA-M
CAS DataBase Reference 1180-95-6(CAS DataBase Reference)
FDA UNII 5PE424S83L

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H335-H319
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
Hazard Codes  Xi
Risk Statements  37
Safety Statements  24/25
WGK Germany  3
3-10
HS Code  29242990

Taurodeoxycholic acid sodium salt price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 580221 Taurodeoxycholic Acid, Sodium Salt - CAS 1180-95-6 - Calbiochem Detergentusefulforthesolubilizationoflipidsandmembrane-boundproteins.A 1180-95-6 5G $182 2024-03-01 Buy
Sigma-Aldrich 580221 Taurodeoxycholic Acid, Sodium Salt - CAS 1180-95-6 - Calbiochem Detergentusefulforthesolubilizationoflipidsandmembrane-boundproteins.A 1180-95-6 50g $745 2024-03-01 Buy
Cayman Chemical 15935 Taurodeoxycholic Acid (sodium salt) ≥95% 1180-95-6 1g $35 2021-12-16 Buy
Cayman Chemical 15935 Taurodeoxycholic Acid (sodium salt) ≥95% 1180-95-6 5g $88 2021-12-16 Buy
Cayman Chemical 15935 Taurodeoxycholic Acid (sodium salt) ≥95% 1180-95-6 25g $350 2021-12-16 Buy
Product number Packaging Price Buy
580221 5G $182 Buy
580221 50g $745 Buy
15935 1g $35 Buy
15935 5g $88 Buy
15935 25g $350 Buy

Taurodeoxycholic acid sodium salt Chemical Properties,Uses,Production

Chemical Properties

white to almost white crystalline powder

Uses

Deoxycholyltaurine rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signaling.

Purification Methods

The Na salt is dissolved in the smallest volume of H2O, a saturated solution of aqueous NaCl/Et2O is added and the mixture is stored at 0o for 24hours. Then shake the mixture well, keep it in the cold for another day and filter the crystals with gentle shaking, wash them with ice-cold saturated aqueous NaCl saturated with Et2O, dry them over CaCl2 and extract them with absolute EtOH. Add ~10mL of H2O to the solid followed by enough Et2O to incipient cloudiness. Store it overnight at 0o. Add ice-cold Et2O to make 250mL, collect the crystals, wash them with Et2O then pet ether and dry them in air. The purification can be repeated with NaCl and Et2O with ~85% recovery. NB: precipitation will not occur unless enough H2O is present. Its solubility in H2O is 10%. [Cortese J Am Chem Soc 59 2532 1937.] The free acid has m 141-144o. [Norman Ark Kemi 8 331 1956.] It forms mixed micelles and solubilises some membrane proteins [Hajjar et al. J Biol Chem 2 5 8 192 1983]. [Beilstein 10 IV 1611.]

107-35-7
83-44-3
1180-95-6
Synthesis of Taurodeoxycholic acid sodium salt from Taurine and Deoxycholic acid

Taurodeoxycholic acid sodium salt Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 261)Suppliers
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Hangzhou MolCore BioPharmatech Co.,Ltd.
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SIMAGCHEM CORP
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Wuhan ChemNorm Biotech Co.,Ltd.
+86-27-8439 4403 18971486879 sales@chemnorm.com CHINA 2935 58

View Lastest Price from Taurodeoxycholic acid sodium salt manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Taurodeoxycholic acid sodium salt pictures 2023-10-16 Taurodeoxycholic acid sodium salt
1180-95-6
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
Taurodeoxycholic acid sodium salt pictures 2023-09-06 Taurodeoxycholic acid sodium salt
1180-95-6
US $0.00-0.00 / KG 1KG 99% 500000kg Hebei Guanlang Biotechnology Co., Ltd.
Taurodeoxycholic acid sodium salt pictures 2023-02-24 Taurodeoxycholic acid sodium salt
1180-95-6
US $0.00 / mg 5mg ≥98%(HPLC) 10 g Shanghai Standard Technology Co., Ltd.
TAURODEOXYCHOLIC ACID SODIUM TAURODEOXYCHOLIC ACID SODIUM SALT SODIUM TAURODEOXYCHOLATE SODIUM SALT SODIUM TAURODESOXYCHOLATE SODIUM SALT 2-[(3ALPHA,12ALPHA-DIHYDROXY-24-OXO-5BETA-CHOLAN-24-YL)-AMINO] ETHANESULFONIC ACID SODIUM SALT 5BETA-CHOLANIC ACID-3ALPHA,12ALPHA-DIOL 24-N-(2-SULFOETHYL)-AMIDE SODIUM 5-BETA-CHOLANIC ACID-3-ALPHA, 12-ALPHA-DIOL N-(2-SULPHOETHYL)-AMIDE SODIUM SALT 3ALPHA,12ALPHA-DIHYDROXY-5BETA-CHOLAN-24-OIC ACID N-[2-SULFOETHYL]AMIDE SODIUM SALT sodium 2-[[(3alpha,5beta,12alpha)-3,12-dihydroxy-24-oxocholan-24-yl]amino]ethane-1-sulphonate Ethanesulfonic acid, 2-(3.alpha.,5.beta.,12.alpha.)-3,12-dihydroxy-24-oxocholan-24-ylamino-, monosodium salt sodium taurodeoxylate Sodium 2-[[(3a,5b,12a)-3,12-dihydroxy-24-oxocholan-24-yl]amino]ethane-1-sulphonate Cholane, ethanesulfonic acid deriv. Sodium deoxytaurocholate Sodium taurodesoxycholate Taurodeoxycholate sodium Taurodeoxycholic acid sodium salt hydrate,97% 2-[(3α,12α-Dihydroxy-24-oxo-5β-cholan-24-yl)amino]ethanesulfonic acid sodium salt 2-[(3α,12α-Dihydroxy-24-oxo-5β-cholane)-24-ylamino]ethanesulfonic acid sodium salt 3α,12α-Dihydroxy-24-[[2-(sodiooxysulfonyl)ethyl]amino]-5β-cholane-24-one N-(3α,12α-Dihydroxy-24-oxo-5β-cholane-24-yl)taurine sodium salt N-[2-(Sodiooxysulfonyl)ethyl]-3α,12α-dihydroxy-5β-cholane-24-oic amide Sodium tarurodeoxycholate 2-(3α,6α-Dihydroxy-24-oxo-5β-cholan-24-ylamino)ethanesulfonic acid sodium salt Sodium Taurodeoxycholic acid Taurodeoxycholic acid sodium salt ,97% Taurodeoxychloic Acid SodiuM Salt SodiuM taurodeoxycholat N-(3α,12α-Dihydroxy-5β-cholan-24-oyl)-taurine MonosodiuM Salt SodiuM 3α,12α-Dihydroxy-5β-cholanoyltaurate SODIUM TAUROUSODEOXYCHOLATE Ursodeoxycholic Impurity 16 sodium 2-[[(3α,5β,12α)-3,12-dihydroxy-24-oxocholan-24-yl]amino]ethane-1-sulphonate Ethanesulfonic Acid,2-[[(3A,5B,12A-3,12-Dihydroxy-24-OxocholaN-24-Yl]Amino]-, Monosodium Salt Sodium 2-((R)-4-((3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)ethanesulfonate Taurodeoxycholic acid sodium saltr Taurodeoxycholic acid sodium salt ISO 9001:2015 REACH sodium 2-[[(3α,5β,12α)-3,12-dihydroxy-24-oxocholan-24-yl]amino]ethane-1-sulphonate Taurodeoxycholicacid (Crude) sodium 2-[[(3α,5β,12α)-3,12-dihydroxy-24-o... Sodium taurodeoxycholate, hydrate, ≥95% (HPLC) )-3,12-dihydroxy-24-oxocholan-24-yl]amino]ethane-1-sulphonate 12B1 5B2 sodium 2-[[(3B1 Sodium Taurodeoxycholate Dried (STDC Dried) extrapure, 97% Taurodeoxycholic acid sodium salt hydrate SODIUM TAURODEOXYCHOLATE Taurodeoxycholate sodium salt Urosodeoxycholic Acid Impurity 16 5β-CHOLANIC ACID-3α, 12α-DIOL N-(2-SULPHOETHYL)-AMIDE SODIUM SALT 1180-95-6 C26H44NNaO6SxH2O C26H44NO6S種a Anionic BioChemical Detergents Chiral Reagents