VALENCENE
- CAS No.
- 4630-07-3
- Chemical Name:
- VALENCENE
- Synonyms
- Valencen;(1R,7R,8aS)-1,2,3,5,6,7,8,8a-Octahydro-1,8a-dimethyl-7-(1-methylethenyl)naphthalene;FEMA 3443;(3R,4aS,5R)-4a,5-Dimethyl-3-(prop-1-en-2-yl)-1,2,3,4,4a,5,6,7-octahydronaphthalene;Naphthalene, 1,2,3,5,6,7,8,8a-octahydro-1,8a-dimethyl-7-(1-methylethenyl)-, (1R,7R,8aS)-;VALENCENE;NSC 148969;Valencene T;VALENCENE 85;VALENCENE775
- CBNumber:
- CB9420232
- Molecular Formula:
- C15H24
- Molecular Weight:
- 204.35
- MDL Number:
- MFCD00075884
- MOL File:
- 4630-07-3.mol
- MSDS File:
- SDS
| Boiling point | 274 °C(lit.) |
|---|---|
| Density | 0.92 g/mL at 25 °C(lit.) |
| FEMA | 3443 | VALENCENE |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
| form | Oil |
| color | Colourless |
| Specific Gravity | 0.92 |
| Odor | at 10.00 % in dipropylene glycol. sweet fresh citrus grapefruit woody orange asprin dry green oily |
| Odor Type | citrus |
| optical activity | [α]22/D +90°, neat |
| Hydrolytic Sensitivity | 1: no significant reaction with aqueous systems |
| JECFA Number | 1337 |
| BRN | 3539153 |
| Stability | Light Sensitive |
| LogP | 6.29 |
| Substances Added to Food (formerly EAFUS) | VALENCENE |
| FDA UNII | 96H21P91IG |
| EPA Substance Registry System | Naphthalene, 1,2,3,5,6,7,8,8a-octahydro-1,8a-dimethyl-7-(1-methylethenyl)-, (1R,7R,8aS)- (4630-07-3) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H304 | |||||||||
| Precautionary statements | P301+P310-P331-P405-P501 | |||||||||
| Safety Statements | 23-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
VALENCENE price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | W344303 | Valencene natural, ≥65% | 4630-07-3 | 25g | $91.3 | 2024-03-01 | Buy |
| Sigma-Aldrich | W344303 | Valencene natural, ≥65% | 4630-07-3 | 100g | $168 | 2024-03-01 | Buy |
| Sigma-Aldrich | W344303 | Valencene natural, ≥65% | 4630-07-3 | 1kg | $1130 | 2024-03-01 | Buy |
| Sigma-Aldrich | 75056 | (+)-Valencene technical, ≥70% | 4630-07-3 | 10g | $135 | 2024-03-01 | Buy |
| Sigma-Aldrich | 75056 | (+)-Valencene technical, ≥70% | 4630-07-3 | 50g | $351 | 2024-03-01 | Buy |
VALENCENE Chemical Properties,Uses,Production
Description
(+)-Valencene is a sesquiterpene that has been found in C. sativa and is an aromatic component of orange essence oil. (+)-Valencene (50 μM) induces heme oxgenase-1 (HO-1) expression in macrophages and inhibits the expression of inducible nitric oxide synthase (iNOS), the production of nitric oxide (NO), and the release of high-mobility group box-1 (HMGB1) in RAW 264.7 cells stimulated with LPS. It also increases the survival rate in a mouse model of sepsis induced by cecal ligation and puncture. (+)-Valencene has been used in the synthesis of nootkatone .
Chemical Properties
clear colorless to yellowish liquid
Occurrence
Reported found in citrus fruits, orange peel, orange juice, bitter orange peel oil, lemon peel oil, grapefruit juice, grapefruit peel oil, kumquat peel oil, leaves and stalk of celery, clove stem, Thymus vulgaris L., fresh mango, globe artichoke, cardamom, mangosteen and cocoa.
Uses
(+)-Valencene can be used as a precursor to prepare:
- (+)-Nootkatone (a sesquiterpene) by dark singlet oxygenation.
- Benzoyloxyvalencene by reacting with tert-butyl peroxy benzoate via Kharasch?Sosnovsky allylic oxidation method.
- (+)-Lineariifolianone, a natural product.
Uses
Valencene is a sesquiterpene and an essential oil component found in a variety of plants, and has been shown to have functional antioxidant, antiradical and antimicrobial properties.
Definition
ChEBI: A carbobicyclic compound and sesquiterpene that is 1,2,3,4,4a,5,6,7-octahydronaphthalene which is substituted a prop-1-en-2-yl group at position 3 and by methyl groups at positions 4a and 5 (the 3R,4aS,5R diastereoisomer).
Preparation
By a Wolf–Kishner reduction of nootkatone.
General Description
Valencene is the major sesquiterpene aroma constituent of orange peel oil. It is mainly used as a starting material to synthesize nootkatone, an important flavor compound of grapefruit.
VALENCENE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12470 | 58 |
| Hebei Guanlang Biotechnology Co,.LTD | +86-19930503253; +8619930503252 | daisy@crovellbio.com | China | 5956 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2503 | 58 |
| Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 | lisa@kingfinertech.com | China | 3003 | 58 |
| airuikechemical co., ltd. | +undefined86-15315557071 | sales01@airuikechemical.com | China | 994 | 58 |
| Ouhuang Engineering Materials (Hubei) Co., Ltd | +8617702722807 | admin@hbouhuang.com | China | 3001 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 2999 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8829 | 58 |
View Lastest Price from VALENCENE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-05-24 | VALENCENE
4630-07-3
|
US $0.00-0.00 / kg | 1kg | 0.99 | 50000kg | Hebei Kingfiner Technology Development Co.Ltd | |
 |
2024-05-16 | VALENCENE
4630-07-3
|
US $32.00 / kg | 1kg | 99% | 5000kg/week | Hebei Zhuanglai Chemical Trading Co.,Ltd | |
 |
2024-04-28 | VALENCENE
4630-07-3
|
US $50.00 / kg | 1kg | 99.10% | 50000kg | Ouhuang Engineering Materials (Hubei) Co., Ltd |