SENKIRKIN
- CAS No.
- 2318-18-5
- Chemical Name:
- SENKIRKIN
- Synonyms
- SENKIKIN;Kushenin;renardin;SENKIRKIN;nsc-89945;RENARIDINE;Senkarkane;senkirkine;renardine[neutral];Renardine (neutral)
- CBNumber:
- CB9427741
- Molecular Formula:
- C19H27NO6
- Molecular Weight:
- 365.42
- MDL Number:
- MFCD01684247
- MOL File:
- 2318-18-5.mol
| Melting point | 197°C |
|---|---|
| Boiling point | 497.19°C (rough estimate) |
| Density | 1.2439 (rough estimate) |
| refractive index | 1.5180 (estimate) |
| storage temp. | -20°C |
| pka | 12.67±0.40(Predicted) |
| LogP | 0.690 (est) |
| EWG's Food Scores | 1 |
| FDA UNII | X65P7V4LVJ |
| IARC | 3 (Vol. 31, Sup 7) 1987 |
SENKIRKIN price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHL89274 | Senkirkine phyproof? Reference Substance | 2318-18-5 | 10MG | $802 | 2024-03-01 | Buy |
| AK Scientific | 2595BB | Senkirkine | 2318-18-5 | 10mg | $860 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FS161626 | Senkirkine | 2318-18-5 | 25mg | $1300 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FS161626 | Senkirkine | 2318-18-5 | 50mg | $2060 | 2021-12-16 | Buy |
| AK Scientific | 2595BB | Senkirkine | 2318-18-5 | 50mg | $2831 | 2021-12-16 | Buy |
SENKIRKIN Chemical Properties,Uses,Production
Description
A further hepatotoxiC alkaloid present in Senecio kirkii Hook, S. renardi and Nardosrnia laevigata. The base has [α]25D - 16° (c 1.89, MeOH) or[α]15D - 6.2° (c 1.91, CHCI3). It forms colourless plates when crystallized from either Me2CO or AcOEt and yields a picrate, m.p. 225.5-226°C and a picrolonate, m.p. 109- 110°C. The ultraviolet spectrum shows a single absorption maximum at 219 mp.. Several crystalline salts and derivatives are known, e.g. the aurichloride, m.p. 182.5-183.5°C; platinichloride, m.p. 196-7°C (dec.); bitartrate, m.p. 201°C; reineckate, m.p. 169-171°C; picrate, m.p. 225- 225.5°C; picrolonate, m.p. 138°C and the methiodide, m.p. 194-6°C (dec.). The O-acetate occurs naturally (q.v.) in Senecio kirkii.
Definition
ChEBI: Senkirkine is a macrolide.
Safety Profile
Poison by ingestion and intraperitoneal routes. Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of Nox
References
Briggs, Mangan, Russell., J. Chern. Soc., 1891 (1948)
Massagetov, Kuzovkov.,J. Gen. Chern., USSR, 23, 158 (1953)
Danilova, Konovalova., ibid, 30, 1921 (1961)
Danilova, Koretskaya, Utkin., ibid, 31, 3815 (1961)
Wunderlich., Chern. Ind., 2089 (1962)
Briggs et al., J. Chern. Soc., 2492 (1965)
SENKIRKIN Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Finetech Industry Limited | +86-27-87465837 +8618971612321 | info@finetechnology-ind.com | China | 9634 | 58 |
| Chengdu Youngshe Chemical Co., Ltd. | +8618108235634 | Cecilia@youngshechem.com | China | 2345 | 58 |
| Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 | 1026@dideu.com | China | 9020 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33350 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
| XI'AN KPC-CN BIOLOGICAL TECHNOLOGY CO.,LTD. | 86-029-85456576 | daisy_wang@vip.163.com | China | 292 | 55 |