D-(+)-アラビトール 化学特性,用途語,生産方法
外観
白色〜わずかにうすい褐色, 結晶性粉末〜粉末
溶解性
水に易溶、90%エタノールに可溶。
解説
アラビトール,無色の結晶．融点103 ℃．[α]D＋7.7°(ホウ砂水)．L-アラビトールはペントース尿症患者の尿中に見いだされる．融点102 ℃．DL-アラビトールは健康体の尿中にエリトリトールとともに存在する．融点105 ℃．
森北出版「化学辞典（第2版）
製造
アラビトール,アラビニトールともいう．ペンチトールの一種．D-アラビトールは，地衣類植物GymnocarpeaeやマッシュルームFistulina hepaticaに遊離状態で多量に存在する．D-アラビノースまたはD-リキソースの還元で得られる．
説明
D-arabinitol is a characteristic metabolic product of candida species. While candida ssp. produces exclusively D-arabinitol, L-arabinitol is developed by the body’s own metabolism. D-arabinitol serum levels increase if candida yeasts proliferate within the organism and cause invasive Candidiasis. Both D-arabinitol and L-arabinitol are present in normal urine, and can easily be measured by gas chromatography of urine samples collected on filter paper.
化学的特性
white to off-white fine crystalline powder
天然物の起源
D-Arabinitol (lyxitol) is found in lichens; in a variety of fungi; in the urediospores of wheat stem rust; in the dried herbiage of the Peruvian shrub, pichi, along with D-mannitol, dulcitol, and perseitol; and in the avocado. It is formed by fermentation of glucose and in 40% yields using blackstrap molasses. D-Arabinitol is formed by catalytic hydrogenation of D-arabinose in the presence of Raney nickel and from the γ-lactones of D-arabinonic and D-lyxonic acids by reduction with sodium borohydride.
使用
D-Arabitol, a rare sugar alcohol, is a substrate used to identify, differentiate and characterize enzyme such as the gluconobacter oxydans dehydrogenase(s), Gox2181, hyperthermophilic D-arabitol dehydrogenase from Thermotoga maritime and NAD-dependent D-arabitoldehydrogenase from acetic acid bacterium, Acetobacter suboxydans.
純化方法
This pentol, which occurs in lichens and fungi, is purified by recrystallisation from 90% EtOH or MeOH. [Ashina & Yamagita Chem Ber 67 801 1934, derivarives: Nakagawa et al. Bull Chem Soc Jpn 40 2150 1967, Prince & Reichstein Helv Chim Acta 20 101 1937, Hough & Theobald Methods in Carbohydrate Chemistry I 94 1962, Academic Press, Beilstein 1 IV 2832.]
D-(+)-アラビトール 上流と下流の製品情報
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準備製品