ガナキソロン

ガナキソロン 価格 もっと(7)

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入
富士フイルム和光純薬株式会社(wako)	W01FLC468419	ガナキソロン GANAXOLONE	38398-32-2	250mg	￥780000	2021-03-23	購入
富士フイルム和光純薬株式会社(wako)	W01COBQJ-2869	ガナキソロン Ganaxolone	38398-32-2	250mg	￥823700	2020-09-21	購入
Sigma-Aldrich Japan	G7795	solid Ganaxolone solid	38398-32-2	5mg	￥30500	2024-03-01	購入
Sigma-Aldrich Japan	G7795	solid Ganaxolone solid	38398-32-2	25mg	￥84500	2024-03-01	購入
富士フイルム和光純薬株式会社(wako)	W01TOC2531	ガナキソロン Ganaxolone	38398-32-2	10mg	￥38000	2021-03-23	購入

ガナキソロン 化学特性,用途語,生産方法

効能

抗てんかん薬, 抗片頭痛薬

説明

Ganaxolone is a 3β-methylated synthetic analog of the neurosteroid allopregnanolone that allosterically enhances GABA_A receptor current. At nanomolar concentrations, it can potentiate GABA-evoked currents at GABA_A receptor complexes containing α₁, α₂, α₃, β₂, and γ_2L subunits expressed in Xenopus oocytes. Ganaxolone has been shown to have a broad range of antiseizure activity in animal epilepsy models and human clinical trials.

使用

Ganaxolone, is synthetic neuroactive steroid, which possess sedative, anxiolytic, and anticonvulsant properties. It is also a potent and selective positive allosteric modulator of GABAA receptors. It is also shown to be used for the treatment of epilepsy.

生物活性

Potent positive allosteric modulator of GABA A receptors. Enhances GABA-evoked chloride currents in Xenopus oocytes expressing GABA A receptors (EC 50 values are 94, 122 and 213 nM for α 2 β 1 γ 2 L , α 3 β 1 γ 2 L and α 1 β 1 γ 2 L receptors respectively). Exerts anticonvulsive effects in a broad range of animal seizure models.

ガナキソロン 上流と下流の製品情報

原材料

準備製品

ガナキソロン 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
Hunan Yuanye Pharmaceutical Co., Ltd.	+8615857615745	2675013845@qq.com	China	87	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10523	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131980	58
Hunan Yuanye Pharmaceutical Co., Ltd.	0731-85589467; 13574065797	2675013845@qq.com	China	33	58
Bayee Biotech (Anqing) Co., Ltd.	0556-0556-5032306 18917961636	wtx@bayeebio.com	China	253	61
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76

38398-32-2(ガナキソロン)キーワード:

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• 38398-32-2
• 3α-hydroxy-3β-methyl-5α-pregnan-20-one
• (3α,5α)-3-Hydroxy-3-methyl-pregnan-20-one
• 1-((3R,5S,8R,9S,10S,13S,14S,17S)-3-Hydroxy-3,10,13-trimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethanone
• (3α,5α)-3-Hydroxy-3-methylpregnan-20-one
• 1-[(3R,5S,8R,9S,10S,13S,14S,17S)-3-hydroxy-3,10,13-trimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]ethanone
• Pregnan-20-one, 3-hydroxy-3-methyl-, (3α,5α)-
• Fampridine Impurity 80
• 5α-PREGNAN-3β-METHYL-3α-OL-20-ONE
• 1-[(Chemicalbook3R,5S,8R,9S,10S,13S,14S,17S)-3-hydroxy-3,10,13-trimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]ethanone
• 3α-hydroxy-3β-methyl-5α-pregnan-20-one
• 5α-PREGNAN-3β-METHYL-3α-
• ガナキソロン
• 3α-ヒドロキシ-3-メチル-5α-プレグナン-20-オン
• 1-[(1S,3aS,3bR,5aS,7R,9aS,9bS,11aS)-7-ヒドロキシ-7,9a,11a-トリメチル-ヘキサデカヒドロ-1H-シクロペンタ[a]フェナントレン-1-イル]エタン-1-オン