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H-ARG-GLY-ASP-SER-OH

H-ARG-GLY-ASP-SER-OH 化学構造式
91037-65-9
CAS番号.
91037-65-9
化学名:
H-ARG-GLY-ASP-SER-OH
别名:
RGDSペプチド;H-ARG-GLY-ASP-SER-OH
英語名:
ARG-GLY-ASP-SER
英語别名:
RGDS;RGDS peptide;ARG-GLY-ASP-SER;RGDS 1/2ACOH 2H2O;L-ARG-GLY-ASP-SER;Arg-Gly-Asp-Ser-OH;H-ARG-GLY-ASP-SER-OH;RGDS/ARG-GLY-ASP-SER;FIBRONECTIN INHIBITOR;Arg-Gly-Asp-Ser, >=98%
CBNumber:
CB9117206
化学式:
C15H27N7O8
分子量:
433.42
MOL File:
91037-65-9.mol
MSDS File:
SDS

H-ARG-GLY-ASP-SER-OH 物理性質

融点 :
183-187℃
比重(密度) :
1.65±0.1 g/cm3(Predicted)
貯蔵温度 :
-20°C
溶解性:
≥21.65 mg/mL in H2O; insoluble in EtOH; insoluble in DMSO
外見 :
白色からオフホワイトの粉末
酸解離定数(Pka):
2.84±0.10(Predicted)
水溶解度 :
1mg/mlで水に溶ける
シーケンス:
H-Arg-Gly-Asp-Ser-OH
安全性情報
  • リスクと安全性に関する声明
  • 危険有害性情報のコード(GHS)
WGK Germany  3
絵表示（GHS） GHS hazard pictograms
注意喚起語 警告
危険有害性情報
コード 危険有害性情報 危険有害性クラス 区分 注意喚起語 シンボル P コード
H302 飲み込むと有害 急性毒性、経口 4 警告 GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 皮膚刺激 皮膚腐食性/刺激性 2 警告 GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 強い眼刺激 眼に対する重篤な損傷性/眼刺激 性 2A 警告 GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 呼吸器への刺激のおそれ 特定標的臓器毒性、単回暴露； 気道刺激性 3 警告 GHS hazard pictograms
注意書き
P261 粉じん/煙/ガス/ミスト/蒸気/スプレーの吸入を避ける こと。
P305+P351+P338 眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。

H-ARG-GLY-ASP-SER-OH 価格 もっと(7)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01BCS4008997
H-Arg-Gly-Asp-Ser-OH 		91037-65-9 25mg ￥51000 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01BCS4008997
H-Arg-Gly-Asp-Ser-OH 		91037-65-9 100mg ￥152000 2024-03-01 購入
Sigma-Aldrich Japan A9041 ≥95% (HPLC)
Arg-Gly-Asp-Ser ≥95% (HPLC)		 91037-65-9 2mg ￥20700 2024-03-01 購入
Sigma-Aldrich Japan A9041 ≥95% (HPLC)
Arg-Gly-Asp-Ser ≥95% (HPLC)		 91037-65-9 5mg ￥23700 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01TOC3498
RGDS peptide 		91037-65-9 10mg ￥57000 2024-03-01 購入

H-ARG-GLY-ASP-SER-OH 化学特性,用途語,生産方法

使用

Arg-Gly-Asp-Ser has been used:
  • to study its effects on cell attachment in rats
  • to analyse the interaction of fibrinogen with erythrocytes occurs through integrin related receptor
  • to pretreat the cells, to assess the role of integrin in the cell attachment process
  • to test its competition with platelet-secreted, nanosheet-adsorbed proteins for binding to glycoprotein IIIa (GPIIIa)

一般的な説明

The tetrapeptide Arg-Gly-Asp-Ser (RGDS) is a key component of the cell attachment domain of fibronectin. The RGDS sequence was found initially to promote the attachment of rat kidney fibroblasts (NRKcells) to fibronectin and synthetic fibronectin peptides coupled to protein-coated plastic. Further investigation indicated that the free RGDS peptide inhibited the attachment of NRK cells to fibronectin coated substrates. The RGDS sequence has been shown to occur in several other proteins, such as the λ receptor on E. coli and the Sindbis coat protein. RGDS is also a target sequence for spirochete adherence of the syphilis bacterium Treponema pallidum.

RGDS has been shown to block fibrinogen-induced aggregation of intact erythrocytes and specific binding of fibrinogen to erythrocyte membranes. The effect of RGDS on transforming growth factor ?1 (TGF?1) mRNA expression and secretion in cultured human mesangial cells has been investigated. RGDS has been utilized in a study of integrin-mediated signal transduction in cultured cells from the sponge Suberites domuncula. RGDS has been demonstrated
to mitigate the binding of Mycobacterium tuberculosis to murine alveolar macrophages

H-ARG-GLY-ASP-SER-OH 上流と下流の製品情報

原材料

L-Ornithine, N2-[(1,1-dimethylethoxy)carbonyl]-N5-[imino[[(4-methylphenyl)sulfonyl]amino]methyl]-, 1H-benzotriazol-1-yl ester L-Serine, N2-[(1,1-dimethylethoxy)carbonyl]-N5-[imino[[(4-methylphenyl)sulfonyl]amino]methyl]-L-ornithylglycyl-L-α-aspartyl-O-(phenylmethyl)-, 3-cyclohexyl 4-(phenylmethyl) ester Nα-(tert-ブチルオキシカルボニル)-ω-(p-トルエンスルホニル)-L-アルギニン

準備製品

H-ARG-GLY-ASP-SER-OH 生産企業

Global( 146)Suppliers
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 sales@sarms4muscle.com China 10523 58
Nextpeptide Inc 		+86-0571-81612335 +8613336028439
 sales@nextpeptide.com China 19915 58

H-ARG-GLY-ASP-SER-OH  スペクトルデータ(1HNMR)

ARG-GLY-ASP-SER(91037-65-9)1HNMR

91037-65-9(H-ARG-GLY-ASP-SER-OH)キーワード:

RGDSペプチド H-ARG-GLY-ASP-OH シクロ(-GLY-ARG-GLY-ASP-SER-PRO-ALA) Sar-Arg-Gly-Asp-Ser-Pro-OH
  • 91037-65-9
  • Fibronectin tetrapeptide
  • L-Arginylglycyl-L-alpha-aspartyl-L-serine
  • L-Serine, L-arginylglycyl-L-alpha-aspartyl-
  • L-Serine, N-(N-(N-L-arginylglycyl)-L-alpha-aspartyl)-
  • arginyl-glycyl-aspartyl-serine
  • RGDS
  • RGDS 1/2ACOH 2H2O
  • L-Serine,N-[N-(N-L-arginylglycyl)-L-a-aspartyl]-
  • L-Serine,L-arginylglycyl-L-a-aspartyl-
  • Arg-Gly-Asp-Ser, >=98%
  • RGDS PEPTIDE;FIBRONECTIN INHIBITOR
  • L-ARG-GLY-ASP-SER
  • H-ARG-GLY-ASP-SER-OH
  • FIBRONECTIN ATTACHMENT PEPTIDE
  • ARG-GLY-ASP-SER
  • ARG-GLY-ASP-SER 1/2ACOH 2H2O
  • RGDS/ARG-GLY-ASP-SER
  • Arg-Gly-Asp-Ser-OH
  • L-Arg-Gly-L-Asp-L-Ser-OH
  • RGDS peptide
  • FIBRONECTIN INHIBITOR
  • H-Arg-Gly-Asp-Ser-OH - CAS 91037-65-9 - Calbiochem
  • Arg-Gly-Asp-Ser, ≥95%(HPLC)
  • L-Serine, L-arginylglycyl-L-α-aspartyl-
  • RGDSペプチド
  • H-ARG-GLY-ASP-SER-OH
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