9,10-ジメトキシ-1-メチルリコレナン-7α-オール

9,10-ジメトキシ-1-メチルリコレナン-7α-オール 化学構造式
477-19-0
CAS番号.
477-19-0
化学名:
9,10-ジメトキシ-1-メチルリコレナン-7α-オール
别名:
リコレニン;9,10-ジメトキシ-1-メチルリコレナン-7α-オール;(1S,8S,10R,17S)-4,5-ジメトキシ-16-メチル-9-オキサ-16-アザテトラシクロ[8.7.0.02,7.013,17]ヘプタデカ-2(7),3,5,12-テトラエン-8-オール
英語名:
lycorenine
英語别名:
ycorenine;lycorenine;lycorenine USP/EP/BP;9,10-Dimethoxy-1-methyllycorenan-7α-ol;(7alpha)-9,10-dimethoxy-1-methyllycorenan-7-ol;(5aR,7S,11bS,11cS)-9,10-dimethoxy-1-methyl-3,5,5a,7,11b,11c-hexahydro-2H-isochromeno[3,4-g]indol-7-ol;(5aR,7S,11bS,11cS)-1,2,3,5,5a,7,11b,11c-Octahydro-9,10-dimethoxy-1-methyl-[2]benzopyrano[3,4-g]indol-7-ol;[2]Benzopyrano[3,4-g]indol-7-ol, 1,2,3,5,5a,7,11b,11c-octahydro-9,10-dimethoxy-1-methyl-,(5aR,7S,11bS,11cS)-
CBNumber:
CB91377212
化学式:
C18H23NO4
分子量:
317.38
MOL File:
477-19-0.mol

9,10-ジメトキシ-1-メチルリコレナン-7α-オール 物理性質

融点 :
199-200℃
沸点 :
477.7±45.0 °C(Predicted)
比重(密度) :
1.28
溶解性:
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
外見 :
Cryst.
酸解離定数(Pka):
11.98±0.20(Predicted)

安全性情報

9,10-ジメトキシ-1-メチルリコレナン-7α-オール 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

9,10-ジメトキシ-1-メチルリコレナン-7α-オール 化学特性,用途語,生産方法

説明

An alkaloid isolated from Lycoris radiata Herb. the base crystallizes from Me2CO in rhombic prisms and has [α]20D + 149.3°. The alkaloid yields crystalline salts and derivatives, e.g. the aurichloride decomposing at 116°C, platinichloride, also decomposing before melting at 210°C; picrate, m.p. 162°C (dec.); monoacetyl derivative, m.p. 185 _7°C. The diacetyl compound has been prepared although with some difficulty and under forcing conditions, m.p. 17 5-6°C. The alkaloid behaves as a pseudo-base giving an oxime hydrochloride which decomposes at 258°C. On catalytic hydrogenation it yields the dihydro-derivative, m.p. 175- 7°C and prolonged hydrogenation eventually forms deoxytetrahydrolycorenine, ClsH2S03N, m.p. 165-8°C although other compounds are also formed at the same time, e.g. C1sH27 0 2N, m.p. l65-7°C and ClsH2S03N, m.p. l20-3°C. The methiodide decomposes when heated at 260°C and on treatment with silver oxide forms two methine bases, of which the (±)-form has been isolated as the methiodide, m.p. 223°C (dec.). The complete structure has been determined primarily from the mass spectrum.

使用

Lycorenine is an antibacterial agent extracted from the bulb of Lycoris radiata.

参考文献

Kondo, Tomimura, Ishiwatari., J. Pharrn. Soc., Japan, 52, 51 (1932) Spectra: Inuka et aI., Tetrahedron Lett., 4745 (1966) Stereochemistry: Mizukami., Tetrahedron, 11,89 (1960)

9,10-ジメトキシ-1-メチルリコレナン-7α-オール 上流と下流の製品情報

原材料

準備製品


9,10-ジメトキシ-1-メチルリコレナン-7α-オール 生産企業

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477-19-0(9,10-ジメトキシ-1-メチルリコレナン-7α-オール)キーワード:


  • 477-19-0
  • lycorenine
  • [2]Benzopyrano[3,4-g]indol-7-ol, 1,2,3,5,5a,7,11b,11c-octahydro-9,10-dimethoxy-1-methyl-,(5aR,7S,11bS,11cS)-
  • 9,10-Dimethoxy-1-methyllycorenan-7α-ol
  • (5aR,7S,11bS,11cS)-9,10-dimethoxy-1-methyl-3,5,5a,7,11b,11c-hexahydro-2H-isochromeno[3,4-g]indol-7-ol
  • (5aR,7S,11bS,11cS)-1,2,3,5,5a,7,11b,11c-Octahydro-9,10-dimethoxy-1-methyl-[2]benzopyrano[3,4-g]indol-7-ol
  • ycorenine
  • lycorenine USP/EP/BP
  • (7alpha)-9,10-dimethoxy-1-methyllycorenan-7-ol
  • リコレニン
  • 9,10-ジメトキシ-1-メチルリコレナン-7α-オール
  • (1S,8S,10R,17S)-4,5-ジメトキシ-16-メチル-9-オキサ-16-アザテトラシクロ[8.7.0.02,7.013,17]ヘプタデカ-2(7),3,5,12-テトラエン-8-オール
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