3-カルボキシラト-1-(5-O-ホスホノ-β-D-リボフラノシル)ピリジニウム 化学特性,用途語,生産方法
使用
A nucleotide of nicotinic acid which is produced from quinolinic acid by quinolinate phosphoribosyltransferase via transfer of a phosphoribose group. It is an intermediate of nicotinic acid adenine dinucleotide (NaAD) which is then converted to NAD via amidation and in turn converted to NADPH.
合成
Nicotinic acid mononucleotide is prepared by the reaction of 2,3-dicarboxypyridine and 5-phosphoribosyl-1-pyrophosphate. The steps are as follows:
With phosphoribosyl pyrophosphate-quinolinate phosphoribosyltransferase; magnesium chloride In aq. phosphate buffer at 37℃; for 6h; pH=7.0; Enzymatic reaction.
3-カルボキシラト-1-(5-O-ホスホノ-β-D-リボフラノシル)ピリジニウム 上流と下流の製品情報
原材料
準備製品