Huperzine A

Huperzine A 구조식 이미지
카스 번호:
120786-18-7
상품명:
Huperzine A
동의어(영문):
SELAGINE;HUPERAZINE A;HUPERZINE A;[+/-]-SELAGINE;(+/-)-SELAGINE;(+/-)-HuperzineA;(+/-)-HUPERZINE A;(+/-)-HUPERAZINE A;(±)-Huperzine A, >98%;Huperzine A USP/EP/BP
CBNumber:
CB0308078
분자식:
C15H18N2O
포뮬러 무게:
242.32
MOL 파일:
120786-18-7.mol

Huperzine A 속성

끓는 점
505.0±50.0 °C(Predicted)
밀도
1.20±0.1 g/cm3(Predicted)
저장 조건
2-8°C
용해도
DMSO : ≥ 50 mg/mL (206.34 mM)
산도 계수 (pKa)
12.25±0.60(Predicted)
물리적 상태
고체
물리적 상태
단단한 모양
색상
흰색 또는 황백색
InChI
InChI=1S/C15H18N2O/c1-3-11-10-6-9(2)8-15(11,16)12-4-5-14(18)17-13(12)7-10/h3-6,10H,7-8,16H2,1-2H3,(H,17,18)/b11-3+
InChIKey
ZRJBHWIHUMBLCN-QDEBKDIKSA-N
SMILES
C12CC3/C(=C\C)/C(N)(C=1C=CC(=O)N2)CC(C)=C3
CAS 데이터베이스
120786-18-7
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 T
위험 카페고리 넘버 23/24/25-36/37/38
안전지침서 26-36/37/39-45
유엔번호(UN No.) UN 1544 6.1/PG 2
WGK 독일 3
RTECS 번호 PB9185700
그림문자(GHS): GHS hazard pictograms
신호 어: Danger
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H315 피부에 자극을 일으킴 피부부식성 또는 자극성물질 구분 2 경고 GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 눈에 심한 자극을 일으킴 심한 눈 손상 또는 자극성 물질 구분 2A 경고 GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 호흡 자극성을 일으킬 수 있음 특정 표적장기 독성 - 1회 노출;호흡기계 자극 구분 3 경고 GHS hazard pictograms
예방조치문구:
P261 분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.
P301+P310 삼켰다면 즉시 의료기관(의사)의 진찰을 받으시오.
P305+P351+P338 눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.

Huperzine A C화학적 특성, 용도, 생산

개요

Huperzine A is an alkaloid extract derived from the Chinese club moss Huperzia serrata. It is an acetylcholinesterase inhibitor. This means it helps promote higher levels of acetylcholine in the brain. Higher levels of acetylcholine support ones ability to perform cognitive tasks such as learning new things, memorizing information, and focusing at the task at hand. Huperzine A is considered to be a nootropic supplement because it supports cognitive function. It is considered a focus and memory nootropic similar to alpha gpc, bacopa, phosphatidylcholine, cdp choline, sulbutiamine, and uridine. It is also considered a brain booster as it is used for brain health and support.
Huperzine A for many years has been widely used in traditional Chinese medicine to enhance memory and to treat fever and inflammation. In the United States it is commercially available as a food supplement, but has not been approved by the FDA as a treatment for AD or other cognition disorders.

출처

The herbs of Lycopodium serratum.

용도

Huperzine A is used for dementia in Alzheimer's disease and for muscle weakness in myasthenia gravis. In Alzheimer's disease, Huperzine A leads to significant improvements in memory and cognitive and behavioral function.

주요 응용

(+/-)-Huperzine A is an NMDA antagonist. It has been used in anti-acetylcholinesterase bioautographic assay.

benefits

Huperzine A can help support learning and memory by protecting acetylcholine, a neurotransmitter that acts as a messenger molecule in the brain. Huperzine A may be used for both short-term "brain boost" needs, such as preparing for a test, as well as more long-term needs, such as reducing the mild memory loss associated with normal aging.
ACETYLCHOLINESTERASE INHIBITOR - Huperzine A acts as a reversible Acetylcholinesterase inhibitor meaning it supports levels of the neurotransmitter acetylcholine which plays a key role in cognitive function.
SUPPORTS COGNITIVE FUNCTION - Supports working memory, motivation, and problem solving ability.
SUPPORTS ENERGY AND STAMINA - Huperzine A supports mental energy, stamina, and sustained focus.

생물학적 활성

Huperzine A is an effective acetylcholinesterase inhibitor and can cross the blood-brain barrier. Huperzine A is known to prevent cognitive defects, glutamate-induced nerve cell death.It is recognized for its use in the treatment of Alzheimer′s disease and organophosphate poisoning.

부작용

When taken at recommended doses Huperzine A is well tolerated and presents few side effects. Rarely, side effects including nausea, diarrhea, and loss of appetite may occur. Adverse side effects are more likely when exceeding the recommended dosage.
Huperzine A is not recommended for people suffering from heart conditions, consult your physician before taking this product.

Mode of action

Huperzine A is a reversible acetycholinesterase inhibitor that can cross the blood-brain barrier. This constituent can inhibit the activity of acetycholinesterase in the brain for several hours, which allows for increased levels of acetylcholine in different areas of the brain. Because of its effects on acetylcholine, Huperzine A is considered a beneficial therapuetic agent in the treatment of memory impairment, myasthenia gravis, and dementia.
Herbs and Nutrients for the Mind A Guide to Natural Brain Enhancers By Chris D. Meletis, Jason E. Barker · 2004

Huperzine A 준비 용품 및 원자재

원자재

준비 용품


Huperzine A 공급 업체

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