네모루비신

네모루비신
네모루비신 구조식 이미지
카스 번호:
108852-90-0
한글명:
네모루비신
동의어(한글):
네모루비신
상품명:
Nemorubicin
동의어(영문):
MMRDX;DMM Dox;FCE 23762;PNU 152243;Nemorubicin;PNU-152243A;Nemorubicina;NeMorubincine;-Dichlorobenzophenone;Nemorubicin (PNU 152243)
CBNumber:
CB11179292
분자식:
C32H37NO13
포뮬러 무게:
643.64
MOL 파일:
108852-90-0.mol

네모루비신 속성

끓는 점
852.2±65.0 °C(Predicted)
밀도
1.55±0.1 g/cm3(Predicted)
저장 조건
Store at -20°C
용해도
DMSO:60.0(Max Conc. mg/mL);101.0(Max Conc. mM)
산도 계수 (pKa)
7.35±0.60(Predicted)
물리적 상태
가루

안전

네모루비신 C화학적 특성, 용도, 생산

용도

Nemorubicin is a doxorubicin derivative that differs significantly from its parent drug in terms of spectrum of antitumor activity, metabolism and toxicity profile. The drug is active on tumors resistant to alkylating agents, topoisomerase II inhibitors and platinum derivatives. It works primarily through topoisomerase I inhibition. Of note, Nemorubicin is active in cells with upregulation of the nucleotide excision repair (NER) pathway, where current therapies fail. Nemorubicin is biotransformed in the liver into cytotoxic metabolites that may further contribute to render this drug highly active against primary liver tumors or liver metastases.

네모루비신 준비 용품 및 원자재

원자재

준비 용품


네모루비신 공급 업체

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ATK CHEMICAL COMPANY LIMITED
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AB PharmaTech,LLC
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United States 989 55
BOC Sciences
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Jurong Coupling Biotechnology Co., Ltd.
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Baoji Guokang Bio-Technology Co., Ltd.
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XI'AN TIANGUANGYUAN BIOTECH CO., LTD.
+86-029-86333380 18829239519
sales06@tgybio.com China 935 58
Wuhan Golt Biotech Co., Ltd.
+8615389281203
maria@goltbiotech.com China 980 58

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