알에이치-폴리펩타이드-7

알에이치-폴리펩타이드-7 속성

알에이치-폴리펩타이드-7 C화학적 특성, 용도, 생산

개요

Somatotropin, a second-generation (methionine-free) human growth hormone produced by recombinant technology, was launched in the U.S.A. for the treatment of growth failure in children due to chronic renal insufficiency before transplantation and for the long term treatment of short stature in children with growth failure due to a lack of endogenous growth hormone secretion. The efficacy of somatotropin is reportedly comparable to the first biosynthetic growth hormone somatrem, which contains a methionyl residue, but with less frequent antibody formation and rarely causes allergic effects or impairs growth response. Somatotropin is also in clinical trials for the treatment of growth hormone deficiency in adults and is currently under approval review for Turner's syndrome.

화학적 성질

White or almost white powder.

World Health Organization (WHO)

Somatropin, a pituitary-derived human growth hormone, has been used in the treatment of hypopituitary dwarfism for over twenty years. In 1985 it became known that Creutzfeldt-Jakob disease, a potentially fatal form of brain degeneration resulting from a slow neurotropic viral infection, had developed in several patients who had received preparations of somatropin in the late 1960s/early 1970s. This led to the withdrawal of these preparations in many countries. An international collaborative effort was maintained to identify newlydiagnosed cases. By 1990 a total of 30 such cases had been notified. More efficient purification procedures introduced during the 1970s greatly reduced the risk of viral contamination, but products containing pituitary-derived somatropin have been superseded by biosynthetically-manufactured preparations produced using recombinant techniques.

일반 설명

Somatropin for injection(Humatrope) is a natural-sequence human GH of rDNAorigin. Its composition and sequence of amino acids areidentical with those of human GH of pituitary origin. It isadministered intramuscularly or subcutaneously. Thedosage range is 0.05 to 0.1 IU.

Clinical Use

Human Growth Hormone (Somatotropin) is a protein that is essential for normal growth and developmentin humans. Human Growth Hormone(hGH) affects many aspects of humandevelopment and metabolism including longitudinalgrowth, regulation (increase) of protein synthesis and lipolysis,and regulation (decrease) of glucose metabolism. Human Growth Hormone(hGH)has been used as a drug since the 1950s, and it has been extremelysuccessful in the treatment of classic growth hormonedeficiency, chronic renal insufficiency, Turner syndrome,failure to lactate in women, and Prader-Willisyndrome. In its long history, the hormone has been remarkablysuccessful and free of side effects.

부작용

Carpal tunnel syndrome.
Increased insulin resistance.
Type 2 diabetes.
Swelling in the arms and legs (edema).
Joint and muscle pain.
For men, enlargement of breast tissue (gynecomastia).
Increased risk of certain cancers.

알에이치-폴리펩타이드-7 준비 용품 및 원자재

원자재

준비 용품

알에이치-폴리펩타이드-7 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Qingdao Sigma Chemical Co., Ltd	+8618661891880	info@sigmachemical.com.cn	China	50	58
Zhuzhou New Peptides Tech Co.,Ltd.	+8618073326374	sales@goodpeptides.com	China	140	58
Shanghai Longyu Biotechnology Co., Ltd.	+8615821988213	info@longyupharma.com	China	2531	58
Changzhou Xuanming Pharmaceutical Technology Co., Ltd.	+8618068519287	sales@xuanmingchem.com	China	823	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10523	58
Hebei Dangtong Import and export Co LTD	+8615632927689	admin@hbdangtong.com	China	984	58
zhuzhou dingcheng meihei comestic co.,ltd	+undefined18873369619	dingchengbusiness8@163.com	China	242	58
Hebei Anlijie Biotechnology Co., Ltd	+8619031013551	ably@aljbio.com	China	189	58
Hebei Miaoyin Technology Co.,Ltd	+86-17367732028 +86-17367732028	kathy@hbyinsheng.com	China	3582	58
CONTIDE BIOTECH CO.,LTD	+852-53358525	xena@healthtide-api.com	China	619	58

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