4'-Nitroacetanilide
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4'-Nitroacetanilide 속성
- 녹는점
- 213-215 °C(lit.)
- 끓는 점
- 312.97°C (rough estimate)
- 밀도
- 1.340
- 굴절률
- 1.6180 (estimate)
- 저장 조건
- Store below +30°C.
- 용해도
- 2.2g/L
- 산도 계수 (pKa)
- 13.91±0.70(Predicted)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- 노란색에서 녹색-노란색 또는 녹색-갈색
- 수용성
- 2.2g/L(상온)
- Merck
- 14,6581
- BRN
- 2211962
- 안정성
- 안정적인. 타기 쉬운. 강한 산화제와 호환되지 않습니다.
- CAS 데이터베이스
- 104-04-1(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 36/37/38 | ||
| 안전지침서 | 26-36 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | AE5075000 | ||
| TSCA | Yes | ||
| HS 번호 | 29242990 | ||
| 독성 | rat,LDLo,intraperitoneal,500mg/kg (500mg/kg),National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. Vol. 5, Pg. 10, 1953. | ||
| 기존화학 물질 | KE-26015 |
4'-Nitroacetanilide C화학적 특성, 용도, 생산
화학적 성질
solid용도
Manufacture of nitraniline.제조 방법
Preparation of 4'-Nitroacetanilide from acetanilide.Principle: Aromatic compounds can be conveniently nitrated by the use of the nitrating mixture, which is normally a mixture of concentrated nitric acid and concentrated sulphuric acid. The function of sulphuric acid is to convert nitric acid into a highly reactive, electrophilic, nitronium ion, NO2+, which is the effective nitrating agent. Nitration of activated aromatic compounds is carried out under milder condition whereas deactivated rings require drastic conditions. Activating groups are o, p-directing, while deactivating groups are m-directing for electrophilic substitution.
Reaction:
Procedure: Take 0.5 g acetanilide in 0.6 ml glacial acetic acid and add 1 ml conc. H2SO4 in a beaker. Cool the mixture in ice salt bath (5-10°C). To this add a mixture of 0.2 ml conc. H2SO4 and 0.25 ml conc. HNO3 dropwise. Maintain the temperature below 10°C during addition. After addition is over allow the mixture to attain room temperature and leave it for 30 minutes. Pour the mixture on to crushed ice (20 g) with stirring. Filter the separated product and wash with cold water. Dry the product, record the practical yield and re-crystallize it.
Re-crystallization: Dissolve the crude product in minimum amount of ethyl alcohol in a beaker by heating on a water bath. Filter the hot solution and cool the filtrate. The crystals of the product separate out. Filter, dry and record the melting point and TLC (using toluene as solvent).
Purification Methods
Precipitate the anilide from 80% H2SO4 by adding ice, then wash with water, and crystallise from aqueous EtOH. Dry it in air. [Beilstein 12 IV 1632.]4'-Nitroacetanilide 준비 용품 및 원자재
원자재
준비 용품
4'-Nitroacetanilide 공급 업체
글로벌( 188)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21689 | 55 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 |
sales@chemdad.com | China | 39916 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49391 | 58 |
| SIMAGCHEM CORP | +86-13806087780 |
sale@simagchem.com | China | 17367 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 |
sales@tnjchem.com | China | 34572 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 |
info@dycnchem.com | CHINA | 52867 | 58 |
| Changzhou Anxuan Chemical Co., Ltd | +86-0519-89882563 +86-18961279162 |
andy@anxuanchem.com | China | 4226 | 58 |
4'-Nitroacetanilide 관련 검색:
피크롤론산 아세트아닐리드 4-플루오로-2-니트로아세타닐라이드
4-NITROPHENYLOXAMIC ACID
N-Benzoyl-DL-arginine-4-nitroanilide hydrochloride
N-(4-NITROPHENYL)MALEIMIDE
N-(4-NITROPHENYL)PHTHALIMIDE
N-(2-METHOXY-4-NITROPHENYL)ACETAMIDE
1-ACETYL-5-NITROINDOLINE
2,4-DINITROACETANILIDE
5-Nitroisatin
4'-Nitroacetanilide
5-Chloro-2-Nitroacetanilide
ALPHA-CHLORO-3-NITROACETANILIDE,N-CHLORO-3-NITROACETANILIDE,Chloro-3-nitroacetanilide, 98%
O-NITROACETANILIDE
ALPHA-CHLORO-2-NITROACETANILIDE,ALPHA-CHLORO-NITROACETANILIDE,ó-chloro-2-nitroacetanilid
4-chloro-3-nitroacetanilide
4-METHOXY-3-NITROACETANILIDE