1-메틸이미다졸
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1-메틸이미다졸 속성
- 녹는점
- −60 °C(lit.)
- 끓는 점
- 198 °C(lit.)
- 밀도
- 1.03 g/mL at 25 °C(lit.)
- 증기압
- 0.4 mm Hg ( 20 °C)
- 굴절률
- n
20/D 1.495(lit.)
- 인화점
- 198 °F
- 저장 조건
- Store below +30°C.
- 용해도
- 클로로포름(약간 용해됨), 메탄올(약간 용해됨)
- 물리적 상태
- 액체
- 산도 계수 (pKa)
- 6.95(at 25℃)
- Specific Gravity
- 1.031
- 색상
- 무색~황색으로 투명함
- 수소이온지수(pH)
- 9.5-10.5 (50g/l, H2O, 20℃)
- pH 범위
- 9.5 - 11.5 at 100 g/l at 20 °C
- 폭발한계
- 2.7-15.7%(V)
- 수용성
- 물과 섞일 수 있습니다.
- 감도
- Hygroscopic
- BRN
- 105197
- 안정성
- 안정적이지만 습기에 민감합니다. 산, 산무수물, 강산화제, 습기, 이산화탄소, 산염화물과 혼합되지 않습니다.
- InChIKey
- MCTWTZJPVLRJOU-UHFFFAOYSA-N
- LogP
- -0.19 at 25℃
- CAS 데이터베이스
- 616-47-7(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | C,Xn,F,T | ||
---|---|---|---|
위험 카페고리 넘버 | 21/22-34-19-11-20/21/22-52/53-24-22-40-37-21 | ||
안전지침서 | 26-36-45-1/2-36/37/39-16-33-29-61 | ||
유엔번호(UN No.) | UN 3267 8/PG 2 | ||
WGK 독일 | 1 | ||
RTECS 번호 | NI7000000 | ||
F 고인화성물질 | 3-10 | ||
자연 발화 온도 | 977 °F | ||
TSCA | Yes | ||
위험 등급 | 8 | ||
포장분류 | III | ||
HS 번호 | 29332990 | ||
독성 | LD50 orally in Rabbit: 1144 mg/kg LD50 dermal Rabbit > 400 - < 640 mg/kg | ||
기존화학 물질 | KE-24298 |
1-메틸이미다졸 C화학적 특성, 용도, 생산
화학적 성질
1-Methylimidazole or N-methylimidazole is an aromatic heterocyclic organic compound with the formula CH3C3H3N2. It is a colorless to yellow liquid, with an amine-like odor. It is miscible with water. N-methylimidazole is an important raw material for the synthesis of pharmaceutical intermediates, used in the preparation of losartan, nizofenone, 1-Methyl-1H-imidazole-5-carbonyl chloride hydrochloride and naphazoline hydrochloride, etc. It is also used as a specialty solvent, a base, and as a precursor to some ionic liquids.용도
1-Methylimidazole is used as a precursor for the synthesis of pyrrole-imidazole polyamides, ionic liquids such as 1-butyl-3-methylimidazolium hexafluorophosphate. It is actively involved in removing acid during the production of diethoxyphenylphosphine. It is used as an intermediate in organic synthesis.용도
1-Methylimidazole is an aprotic solvent. It is a derivative of imidazole used in the production of pharmaceuticals, pesticides, ion exchange resins, dye intermediates, textile auxiliaries, photographic chemicals, and corrosion inhibitors. It can also be used as a catalyst for the manufacture of polyurethane and a curing agent for epoxy resins. For example, when 1-methylimidazole is added to an aqueous diethylenetriamine (DETA) solution, high CO2 loading can be achieved through phase separation of the absorbent during CO2 absorption[1].제조 방법
1-Methylimidazole is prepared mainly by two routes industrially. The main one is acid-catalysed methylation of imidazole by methanol. The second method involves the Radziszewski reaction from glyoxal, formaldehyde, and a mixture of ammonia and methylamine.(CHO)2 + CH2O + CH3NH2 + NH3 → H2C2N(NCH3)CH + 3 H2O
The compound can be synthesized on a laboratory scale by methylation of imidazole at the pyridine-like nitrogen and subsequent deprotonation. Similarly, 1-methylimidazole may be synthesized by first deprotonating imidazole to form a sodium salt followed by methylation.
H2C2N(NH)CH + CH3I → [H2C2(NH)(NCH3)CH]I
[H2C2(NH)(NCH3)CH]I + NaOH → H2C2N(NCH3)CH + H2O + NaI
정의
ChEBI: 1-methyl-1H-imidazole is a 1H-imidazole having a methyl substituent at the N-1 position. It is a metabolite of 1-methyl-2-thioimidazole (methimazole). It inhibits bone resorption.일반 설명
This product has been enhanced for catalysis. 1-Methylimidazole is a derivative of imidazole that is utilized in the manufacture of such classes of items as pharmaceuticals, pesticides, ion-exchange resins, dye intermediates, textile auxiliaries, photographic chemicals, and corrosion inhibitors. It is also used as a catalyst for manufacturing polyurethanes and a curing agent for epoxy resins.Purification Methods
Dry it with sodium metal and then distil it. Store it at 0o under dry argon. The picrate has m 159.5-160.5o (from H2O). [Beilstein 23 III/IV 568.]1-메틸이미다졸 준비 용품 및 원자재
원자재
준비 용품
1-Ethyl-3-methylimidazolium tetrafluoroborate
1-Methyl-2-imidazolecarboxaldehyde
1-METHYL-1H-IMIDAZOLE-2-CARBONYL CHLORIDE,97%
1-Butyl-3-methylimidazolium tetrafluoroborate
1H-이미다졸, 4,5-다이하이드로-2-(1-나프탈레닐메틸)-,모노하이드로클로라이드
ETHYL 1-METHYL-1H-IMIDAZOLE-2-CARBOXYLATE
1-ETHYL-3-METHYLIMIDAZOLIUM DICYANAMIDE
크롤피리포스
Nizofenone
1-Butyl-3-methylimidazolium bromide
1-Butyl-3-methylimidazolium hexafluorophosphate
1-Methyl-1H-imidazole-2-carboxylic acid
1-Methyl-1H-imidazole-5-carbonyl chloride hydrochloride
1-ETHYL-3-METHYLIMIDAZOLIUM BIS(TRIFLUOROMETHYLSULFONYL)IMIDE
Losartan
클로르피리포스-메틸
ETHYL 2-(1-METHYL-1H-IMIDAZOL-2-YL)-2-OXOACETATE
1-플루오로-4-아이오도벤젠
1-메틸이미다졸 공급 업체
글로벌( 820)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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Anhui Ruihan Technology Co., Ltd | +8617756083858 |
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