ChemicalBook >제품 카탈로그 >CIS-N-BENZYL-3-METHYLAMINO-4-METHYL-PIPERIDINEBIS-(염화물)

CIS-N-BENZYL-3-METHYLAMINO-4-METHYL-PIPERIDINEBIS-(염화물)

CIS-N-BENZYL-3-METHYLAMINO-4-METHYL-PIPERIDINEBIS-(염화물) 구조식 이미지

카스 번호:: 1062580-52-2

한글명:: CIS-N-BENZYL-3-METHYLAMINO-4-METHYL-PIPERIDINEBIS-(염화물)

동의어(한글):: CIS-N-BENZYL-3-METHYLAMINO-4-METHYL-PIPERIDINEBIS-(염화물)

상품명:: (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride

동의어(영문):: (3R,4R)-N,4-Dimethyl-1-(phenylmethyl)-3-piperidinamine hydrochloride;TOF30;Tofacitinib-1;Tofatinib Impurity 5;Tofacitinib interMediate A;Tofacitinib intermediate 3;piperidin-3-amine dihydrochL;Tofacitinib Impurity 123 DiHCl;Azilsartan medoxomil impurity351;Tofacitinib Impurity 5 Dihydrochloride

CBNumber:: CB21011155

분자식:: C14H23ClN2

포뮬러 무게:: 254.8

MOL 파일:: Mol file

속성

안전

용도

공급 업체 359

CIS-N-BENZYL-3-METHYLAMINO-4-METHYL-PIPERIDINEBIS-(염화물) 속성

녹는점: 249～251℃

저장 조건: under inert gas (nitrogen or Argon) at 2-8°C

용해도: 수용액(약간 용해됨), DMSO(약간 용해됨, 가열, 초음파 처리), 메탄올(약간 용해됨)

물리적 상태: 고체

물리적 상태: 단단한 모양

색상: 흰색에서 황백색까지

InChI: InChI=1/C14H22N2.ClH/c1-12-8-9-16(11-14(12)15-2)10-13-6-4-3-5-7-13;/h3-7,12,14-15H,8-11H2,1-2H3;1H/t12-,14+;/s3

InChIKey: FVRZQLQXDPJADE-WLZBWWFYNA-N

SMILES: C(C1C=CC=CC=1)N1CC[C@@H](C)[C@@H](NC)C1.Cl |&1:10,12,r|

안전

위험 및 안전 성명
위험 및 사전주의 사항 (GHS)

위험 등급	IRRITANT
HS 번호	2933399990

그림문자(GHS):

신호 어:

Warning

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	그림 문자	P- 코드
H302	삼키면 유해함	급성 독성 물질 - 경구	구분 4	경고		P264, P270, P301+P312, P330, P501

예방조치문구:

P264	취급 후에는 손을 철저히 씻으시오.
P264	취급 후에는 손을 철저히 씻으시오.
P270	이 제품을 사용할 때에는 먹거나, 마시거나 흡연하지 마시오.
P301+P312	삼켜서 불편함을 느끼면 의료기관(의사)의 진찰을 받으시오.
P330	입을 씻어내시오.
P501	...에 내용물 / 용기를 폐기 하시오.

CIS-N-BENZYL-3-METHYLAMINO-4-METHYL-PIPERIDINEBIS-(염화물) C화학적 특성, 용도, 생산

용도

(3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.

Synthesis

TiCl4(0.2g, 1mmol) and NEt3(0.15 g, 1.5 mmol) were added to toluene, and then add 1-benzyl-4-methyl-3-ketone piperidine (20.3 g, 100 mmol) at 35 ℃. The methylamine solution is added to the reaction solution (9.32 g, 120 mmol) and reaction for 4 h, followed by adding NaBH (OAC) 3 (0.32 g, 1.5 mmol) and glacial acetic acid 2 ml. After the reaction is complete, add saturated salt water to wash the reaction mixture. (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride was obtained after further purification.

CIS-N-BENZYL-3-METHYLAMINO-4-METHYL-PIPERIDINEBIS-(염화물) 준비 용품 및 원자재

원자재

(3R,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine 1-벤질-N,4-디메틸피페리딘-3-아민이염화물 1-벤질-4-메틸피페리딘-3-온 (1-벤질-4-메틸-1,2,5,6-테트라하이드로피리딘-3-일)카르바민산메틸에스테르 Methanamine Acetate 3-Amino-4-methylpyridine

준비 용품

CIS-N-BENZYL-3-METHYLAMINO-4-METHYL-PIPERIDINEBIS-(염화물) 공급 업체

글로벌( 359)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Changsha Junyu Chemexpress.co., Ltd	+86-13723890100	info@csjyyy.cn	China	134	58
Shanghai Boc Chemical Co., Ltd.	021-34975602; +8618721111801	shangli@bocchem.com	China	138	58
Purest Pharmaceuticl （Xi’an) Co,.LTD	+8613893405577	12829054@qq.com	China	74	58
Hangzhou ICH Biofarm Co., Ltd	+86-0571-28186870; +undefined8613073685410	sales@ichemie.com	China	985	58
hebei hongtan Biotechnology Co., Ltd	+86-86-1913198-3935 +8617331935328	sales03@chemcn.cn	China	952	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1811	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21688	55
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9341	55
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3012	60

CIS-N-BENZYL-3-METHYLAMINO-4-METHYL-PIPERIDINEBIS-(염화물) 관련 검색:

(1-Benzyl-4-Methyl-1,2,5,6-tetrahydropyridin-3-yl)carbaMic acid Methyl ester Methyl (1-benzyl-4-Methylpiperidin-3-yl)carbaMate 13-Deoxyepirubicin 3-((3R,4S)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitrile 3-METHOXYCARBONYLAMINO-4-METHYLPYRIDINE 1-[2-(2-methoxyphenoxy)ethylamino]-3-(9-methylcarbazol-4-yl)oxypropan-2-ol:hydrochloride Methyl (4-Methylpiperidin-3-yl)carbaMate 3-((3S,4R)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitrile 3-PiperidinaMine, 1-acetyl-N,4-diMethyl-N-1H-pyrrolo[2,3-d]pyriMidin-4-yl-, (3R,4R)- (9CI) 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (3R,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine 2,4-DICHLORO-7H-PYRROLO2,3-DPYRIMIDINE 7H-Pyrrolo[2,3-d]pyriMidin-4-aMine, N-Methyl-N-[(3R,4R)-4-Methyl-1-(phenylMethyl)-3-piperidinyl]-7-[(4-Met hylphenyl)sulfonyl]- 4-CHLORO-7-TOSYL-7H-PYRROLO[2,3-D]PYRIMIDINE Tofacitinib citrate 3-bis(4-Methylbenzoyloxy)succinate)