HKPao

HKPao 구조식 이미지
카스 번호:
859216-15-2
상품명:
HKPao
동의어(영문):
HKPao;Adipotide Powder;Weight Loss Peptides Adipotide Adipotide Ftpp;D-Lysine, L-cysteinyl-L-lysylglycylglycyl-L-arginyl-L-alanyl-L-lysyl-L-α-aspartyl-L-cysteinylglycylglycyl-D-lysyl-D-leucyl-D-alanyl-D-lysyl-D-leucyl-D-alanyl-D-lysyl-D-lysyl-D-leucyl-D-alanyl-D-lysyl-D-leucyl-D-alanyl-
CBNumber:
CB29766880
분자식:
C111H206N36O28S2
포뮬러 무게:
2557.21
MOL 파일:
859216-15-2.mol

HKPao 속성

밀도
1.40±0.1 g/cm3(Predicted)
InChIKey
GZESIPHLGJDZRG-XRIURATCNA-N

안전

HKPao C화학적 특성, 용도, 생산

개요

HKPao (Hunter-killer peptide ao) is a biologically active peptide. HKPao (Hunter-killer peptide ao) has anti-obesity and anti-tumor pro-apoptotic activity to cause release of cytochrome c from vesicles.

benefits

Hunter killer peptides (HKPs) use receptor interactions as a vehicle for intracellular delivery and have been reported for targeting angiogenic tumor vasculature, white adipose tissue, and arthritic tissue. These pro-apoptotic peptides contain a variable amino terminal homing sequence, which mediates interactions with cell surface receptors, and a common positively charged carboxyl terminal apoptosis sequence motif that is connected through a glycinyl glycine linker. Once inside the cell, the peptide initiates apoptosis through a membrane perturbing interaction with the mitochondria. The apoptotic sequence is comprised of D-amino acids to increase the in vivo stability. The amino acids of the pro-apoptotic sequence of HKP1 and HKPao have D-stereochemical configuration and are shown in lower case letters. HKP1 and HKPao can induce leakage of fluorescent dextrans from vesicles that have a larger hydrodyanmic radius than cytochrome c. Similar size dependence profiles suggest that the size of the transient pores formed by both these peptides are the same[1].

HKPao 준비 용품 및 원자재

원자재

준비 용품


HKPao 공급 업체

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