2'-O-(2-Methoxyethyl)cytidine
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2'-O-(2-Methoxyethyl)cytidine 속성
- 끓는 점
- 535.3±60.0 °C(Predicted)
- 밀도
- 1.57±0.1 g/cm3(Predicted)
- 저장 조건
- 2-8°C
- 용해도
- DMSO : 250 mg/mL (829.74 mM)
- 산도 계수 (pKa)
- 13.36±0.70(Predicted)
- InChI
- InChI=1S/C12H19N3O6/c1-19-4-5-20-10-9(17)7(6-16)21-11(10)15-3-2-8(13)14-12(15)18/h2-3,7,9-11,16-17H,4-6H2,1H3,(H2,13,14,18)/t7-,9-,10-,11-/m1/s1
- InChIKey
- YKOGMMXZKKVMBT-QCNRFFRDSA-N
- SMILES
- OC[C@H]1O[C@@H](N2C=CC(N)=NC2=O)[C@H](OCCOC)[C@@H]1O
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
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유해·위험 문구: |
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예방조치문구: |
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2'-O-(2-Methoxyethyl)cytidine C화학적 특성, 용도, 생산
용도
A cytidine derivative as building blocks for cross-linking oligonucleotides.Synthesis
2'-O-(2-Methoxyethyl)uridine could be converted into the corresponding cytidine derivative (2'-O-(2-Methoxyethyl)cytidine) by the 4-nitrophenylation[1]. 2'-O-(2-Methoxyethyl)uridine, l-methylpyrrolidine, chlorotrimethylsilane and dry acetonitrile were stirred together at rt. After 1 h, the reaction mixture was cooled to 0 ℃, and trifluoroacetic anhydride was added dropwise over 5 min. After a further period of 30 rain at 0 ℃, 4-nitrophenol was added to the stirred reactants which were maintained at 0 °C. After 3 h, the products were poured into saturated aqueous sodium hydrogen carbonate, and the resulting mixture was extracted with dichloromethane. The combined organic layers were dried, and evaporated under reduced pressure. Concentrated aqueous ammonia was added to a stirred solution of the residue in dioxane, contained in a sealed flask that was then heated at 55°C for 24 h. The resulting yellow solution was concentrated under reduced pressure and the residue was evaporated with absolute ethanol. The products were fractionated by short column chromatography on silica gel and were evaporated under reduced pressure to give 2'-O-(2-Methoxyethyl)cytidine as an off-white solid.2'-O-(2-Methoxyethyl)cytidine 준비 용품 및 원자재
원자재
준비 용품
2'-O-(2-Methoxyethyl)cytidine 공급 업체
글로벌( 87)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Yunbio Tech Co.,Ltd. | +86-010-60605551 +86-18046518538 |
yunbiochem@126.com | China | 321 | 58 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 |
admin@nexconn.com | China | 10247 | 58 |
Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 |
figo.gao@foxmail.com | China | 7019 | 58 |
Nanjing Baifuli Technology Co., Ltd. | +86-15335185688 |
sales@unisyn.cn | CHINA | 332 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49391 | 58 |
career henan chemical co | +86-0371-86658258 15093356674; |
factory@coreychem.com | China | 29826 | 58 |
Antai Fine Chemical Technology Co.,Limited | 18503026267 |
info@antaichem.com | CHINA | 9641 | 58 |
SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 |
contact@trustwe.com | China | 5738 | 58 |
Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 |
sale04@alfachem.cn | China | 12740 | 58 |
BOC Sciences | +16314854226 |
inquiry@bocsci.com | United States | 19743 | 58 |
2'-O-(2-Methoxyethyl)cytidine 관련 검색:
2'-O-Methylcytidine
DMT-2μ-O-Me-rG(ib) amidite
2’-O-Methyl-rA(N-Bz)phosphoramidite
DMT-2′Fluoro-dU Phosphoramidite
2'-O-MOE-A(Bz)-3'-phosphoramidite
2'-O-(2-Methoxyethyl)-5-methyluridine
N-blocked-5'-O-DMT-2'-O-Me CED cytosine phosphoramidite
N4-Benzoyl-5'-O-DMT-2'-O-methyl-5-methylcytidine 3'-CE phosphoramidite
Dmt-2'-f-dc(ac) amidite
2'-O-Methyladenosine
2'-O-Methylguanosine
2'-O-(2-Methoxyethyl)uridine
DMT-2'-O-MOE-rU Phosphoramidite
2'-O-MOE-ADENOSINE
2'-OMe-ibu-G Phosphoramidite
2'-O-(2-Methoxyethyl)guanosine