시토신
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시토신 속성
- 녹는점
- >300 °C (lit.)
- 끓는 점
- 208.2°C (rough estimate)
- 밀도
- 0,48 g/cm3
- 굴절률
- 1.5000 (estimate)
- 저장 조건
- 2-8°C
- 용해도
- 0.5M HCL에 용해된 50mg/ml의 투명하거나 매우 약간 흐릿한 무색 내지 희미한 노란색 용액.
- 물리적 상태
- 결정성 분말
- 산도 계수 (pKa)
- 4.60, 12.16(at 25℃)
- 색상
- 흰색에서 약간 노란색
- 수용성
- 녹는
- Merck
- 14,2795
- BRN
- 2637
- 안정성
- 안정적인. 강한 산화제와 호환되지 않습니다.
- InChIKey
- OPTASPLRGRRNAP-UHFFFAOYSA-N
- LogP
- -1.962 (est)
- CAS 데이터베이스
- 71-30-7(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xi,Xn | ||
---|---|---|---|
위험 카페고리 넘버 | 36/37/38-20/21/22 | ||
안전지침서 | 26-36-37/39 | ||
WGK 독일 | 1 | ||
RTECS 번호 | UW7350150 | ||
위험 참고 사항 | Irritant | ||
TSCA | Yes | ||
HS 번호 | 29335910 |
시토신 C화학적 특성, 용도, 생산
개요
Cytosine is pyrimidine; along with adenine and guanine they account for the fi ve nucleic acid bases. Pyrimidines are heterocyclic single-ringed compounds based on the structure of pyrimidine. Cytosinelike adenine and guanine, form nucleosides and nucleotides in RNA and DNA. When the bases combine with ribose, a ribonucleoside forms; and when it attaches to deoxyribose, a deoxyribosenucleoside is formed. Names of the nucleoside are summarized in Table 29.1.these in turn combine with phosphoryl groups, in a process called phosphorylation, to form their respective nucleotides that form nucleic acids.the nucleotides can be tri, di, and mono phosphate nucleotides similar to the way in which adenine forms ATP, ADP, and AMP.화학적 성질
White Solid역사
Cytosine is first isolated by hydrolysis of calf thymus tissue by Albrecht Kossel (1853–1927) and A. Neumann during 1893–1894. Thymine’s structure was published in 1900 and confi rmed over the next several years when it was synthesized by several investigators. In 1903, cytosine was synthesized by Henry Lord Wheeler (1867–1914) and Treat B. Johnson, confirming its structure. Uracil was first isolated in 1900 from yeast nucleic acid found in bovine thymus and herring sperm.the methylation of uracil produces thymine; thymine is also called 5-methyluracil because methylation takes place at the fi fth carbon in uracil to produce thymine.용도
Cytosine is a nucleoside used for proteomics research. It is also used as an enzyme substrate or precursor of effector molecules such as cytosine sugars.정의
A nitrogenous base found in DNA and RNA. Cytosine has the pyrimidine ring structure.일반 설명
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.Purification Methods
Cytosine crystallises from H2O as the monohydrate which loses water on heating above 100o. Its solubility in H2O is 0.77%. UV: max 267nm ( 6,100) in H2O pH 8.8 and 275nm ( 10,400) in 0.1N HCl. [Hilbert & Johnson J Am Chem Soc 52 1152 1930, Hilbert et al. J Am Chem Soc 57 552 1935, Beistein 25 III/IV 3654.]Structure and conformation
Cytosine is a pyrimidine containing a single heterocyclic aromatic ring, a keto group at C2, and an amine group at C4. The molecule is planar in shape. Cytosine can form three hydrogen bonds with guanine. Due to these three hydrogen bonds, the cytosine-guanine base pair has an overall higher boiling point and greater bond strength than the adenine-thymine base pair. The high melting point makes the cytosine-guanine base-pair much more resistant to denaturation. The double strand of DNA breaks down into its single constituent strands due to high temperatures.시토신 준비 용품 및 원자재
원자재
준비 용품
6-AMINO-5-BROMOPYRIMIDIN-2(1H)-ONE
시티콜린
4-AMINO-5-BROMO-2-PYRIMIDINOL
Cidofovir
2''-디옥시-5-요오드유리딘
5-IODOCYTOSINE
4-Pyrimidinol
3-메틸시토신
5-메틸시토신
4-Amino-1-3,5-di-O-benzoyl-2-deoxy-2,2-difluoro-a-D-erythro-pentofuranosyl)-2(1H)-pyrimidinone
N-(Trimethylsilyl)-2-[(trimethylsilyl)oxy]pyrimidin-4-amine
카르밤산,(1,2-디하이드로-2-옥소-4-피리미디닐)-,1,1-디메틸에틸에스테르(9CI)
6-AMINO-5-(1-PIPERIDINYLMETHYL)-2(1H)-PYRIMIDINONE
1-phenyl-cytosine
시토신 공급 업체
글로벌( 833)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Hangzhou Measure Life Technology Co., LTD | +8613343730176 |
2924244016@qq.com | China | 83 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12469 | 58 |
Henan Bao Enluo International TradeCo.,LTD | +86-17331933971 +86-17331933971 |
deasea125996@gmail.com | China | 2503 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 18218 | 58 |
hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 |
sales03@chemcn.cn | China | 952 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21688 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9341 | 55 |
Hubei XinRunde Chemical Co., Ltd. | +8615102730682 |
bruce@xrdchem.cn | CHINA | 566 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32715 | 60 |