GW0742
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GW0742 속성
- 녹는점
- 134.5-135.5 °C
- 끓는 점
- 591.5±60.0 °C(Predicted)
- 밀도
- 1.46±0.1 g/cm3(Predicted)
- 저장 조건
- 2-8°C
- 용해도
- DMSO: >5mg/mL
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 3.17±0.10(Predicted)
- 색상
- 하얀색
- InChI
- InChI=1S/C21H17F4NO3S2/c1-11-7-14(4-6-17(11)29-9-19(27)28)30-10-18-12(2)26-20(31-18)13-3-5-15(16(22)8-13)21(23,24)25/h3-8H,9-10H2,1-2H3,(H,27,28)
- InChIKey
- HWVNEWGKWRGSRK-UHFFFAOYSA-N
- SMILES
- C(O)(=O)COC1=CC=C(SCC2SC(C3=CC=C(C(F)(F)F)C(F)=C3)=NC=2C)C=C1C
안전
| WGK 독일 | 3 | ||
|---|---|---|---|
| HS 번호 | 38220090 |
GW0742 C화학적 특성, 용도, 생산
개요
GW0742 is a PPARδ/β agonist very similar in molecular structure to GW501516 (Cardarine) — with the exception of one atom. It is often mentioned in comparison with Cardarine. This drug is mostly used by athletes to improve their stamina. The fat affecting properties of GW0742 also make it a good promoter of energy in the body. Additionally, this drug helps increase the oxidative abilities of your body muscles.화학적 성질
Light Yellow Solid용도
GW0742 is a small molecule agonist of the human Peroxisome Proliferator-Activated Recept δ (PPAR δ). It shows an EC50 of 1.1 nM against PPAR δ with 100-fold selectivity over the other human subtypes.생물학적 활성
GW 0742 is a potent and highly selective PPARδ agonist. EC50 values are 0.001, 1.1 and 2 μM for transactivation of human PPARδ, -α, and -γ receptors respectively. Neuroprotective in rat cerebellar granule neuronal cultures after brief (12-hour) exposure but exhibits inherent toxicity after prolonged (48-hour) incubation. Increases rate of fatty acid oxidation and protects against ischemia/reperfusion injury in neonatal and adult cardiomyocytes.GW0742 준비 용품 및 원자재
원자재
준비 용품
GW0742 공급 업체
글로벌( 204)공급 업체
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| Shanghai Aosiris new Material Technology Co., LTD | 86-15139564871 +8615139564871 |
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