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카루모난

카루모난 구조식 이미지

카스 번호:: 87638-04-8

한글명:: 카루모난

동의어(한글):: 카루모난

상품명:: CARUMONAM

동의어(영문):: AMA 1080;CARUMONAM;Ro 17-2301;CarlliIIonaln;CARUMONAM USP/EP/BP;Ro-17-2301：A-masulin;Antibiotic Ro 17-2301;(2S)-2α-(Carbamoyloxymethyl)-3α-[[(Z)-(2-amino-4-thiazolyl)[(carboxymethoxy)imino]acetyl]amino]-4-oxoazetidine-1-sulfonic acid;[[[(Z)-2-[[(2S)-2α-[[(Aminocarbonyl)oxy]methyl]-4-oxo-1-sulfoazetidin-3α-yl]amino]-1-(2-aminothiazol-4-yl)-2-oxoethylidene]amino]oxy]acetic acid;[[[(Z)-2-[[(2S,3S)-2-[[(Aminocarbonyl)oxy]methyl]-4-oxo-1-sulfoazetidin-3-yl]amino]-1-(2-amino-4-thiazolyl)-2-oxoethylidene]amino]oxy]acetic acid

CBNumber:: CB5165269

분자식:: C12H14N6O10S2

포뮬러 무게:: 466.4

MOL 파일:: 87638-04-8.mol

속성

안전

용도

공급 업체 34

카루모난 속성

알파: D26 -45° (c = 1 in DMSO)

밀도: 2.13±0.1 g/cm3(Predicted)

산도 계수 (pKa): -0.43±0.60(Predicted)

안전

카루모난 C화학적 특성, 용도, 생산

개요

Canunonam is an injectable antibiotic, the second monobactam ever developed (the first being Squibb’s aztreonam). It is highly active against Gram negative bacteria, particularly pseudomom, and is reportedly effective in the treatment of pneumonia, cystitis, peritonitis and secondary infections.

정의

ChEBI: An N-sulfonated monobactam antibiotic.

Antimicrobial activity

A synthetic monobactam with activity against common pathogenic organisms similar to that of aztreonam. It is resistant to hydrolysis by the common plasmid and chromosomal β-lactamases, but it can be hydrolyzed by ESBLs.
It is administered intravenously, achieving a concentration of c. 78 mg/L after a 20-min infusion of 1 g. The plasma halflife is 1.7 h and the plasma protein binding 18–28%. Carumonam is almost entirely eliminated in the glomerular filtrate, probenecid having no effect on excretion; 96% of labeled compound is found in the urine, with 3% in the feces. Between 68% and 91% of the dose appears in the urine within 24 h.
Side effects and clinical use are similar to those of aztreonam.

카루모난 준비 용품 및 원자재

원자재

나트륨 붕소수화물 벤질 클로로탄소산 (+)-디-p-톨루오일-D-주석산

준비 용품

카루모난 공급 업체

글로벌( 34)공급 업체

공급자	전화	이메일	국가	제품 수	이점
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-87569265 +86-18612256290	1056@dideu.com	China	2929	58
SIMAGCHEM CORP	+86-13806087780	sale@simagchem.com	China	17367	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	1026@dideu.com	China	9126	58
AFINE CHEMICALS LIMITED	+86-0571-85134551	info@afinechem.com	China	15396	58
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14059	65
Beijing HuaMeiHuLiBiological Chemical	010-56205725	waley188@sohu.com	China	12338	58
Nanjing Sunlida Biological Technology Co., Ltd.	025-57798810	sales@sunlidabio.com	China	3750	55
GIHI CHEMICALS CO.,LTD	0086-571-86217390	Sales@gihichem.com	China	861	58

카루모난 관련 검색:

아조트리오남 DATMA CEFIXIME CARUMONAM CARUMONAM INTERMEDIATE (2S-trans)-3-Amino-2-methyl-4-oxoazetidine-1-sulphonic acid (S)-2-AZETIDINEMETHANOL Carumonam disodium salt CARUMONAM