2-Fluoro-N-Methyl-5-nitroaniline

2-Fluoro-N-Methyl-5-nitroaniline 구조식 이미지
카스 번호:
110729-51-6
상품명:
2-Fluoro-N-Methyl-5-nitroaniline
동의어(영문):
2-Fluoro-N-Methyl-5-nitroaniline;Benzenamine, 2-fluoro-N-methyl-5-nitro-
CBNumber:
CB52710955
분자식:
C7H7FN2O2
포뮬러 무게:
170.14
MOL 파일:
110729-51-6.mol

2-Fluoro-N-Methyl-5-nitroaniline 속성

끓는 점
270.3±30.0 °C(Predicted)
밀도
1.361±0.06 g/cm3(Predicted)
산도 계수 (pKa)
2.12±0.25(Predicted)
InChI
InChI=1S/C7H7FN2O2/c1-9-7-4-5(10(11)12)2-3-6(7)8/h2-4,9H,1H3
InChIKey
YWKHWTYJUYVMND-UHFFFAOYSA-N
SMILES
C1(NC)=CC([N+]([O-])=O)=CC=C1F

안전

HS 번호 2921490090

2-Fluoro-N-Methyl-5-nitroaniline C화학적 특성, 용도, 생산

용도

2-Fluoro-N-Methyl-5-nitroaniline can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical and pharmaceutical production process.

Synthesis

Synthesis_110729-51-6
2-fluoro-5-nitroaniline (20.0g, 128.2mmol) and paraformaldehyde (16.0g, 533.3mmol) was dissolved in 500mL of methanol then stirred at room temperature. Then added dropwise NaOMe (3.4g, 63mmol) in methanol 100mL. The reaction was stirred at room temperature for 16 hours then was added NaBH4 (9.7g, 255.2mmol) in two aliquots, stirred for 15 minutes. LCMS traced the reaction. After completion of the reaction was poured into 1M KOH aqueous solution, and stirred to precipitate a solid. Filtered to give a yellow solid 2-fluoro-N-methyl-5-nitroaniline (19.0g, 87% yield).

2-Fluoro-N-Methyl-5-nitroaniline 준비 용품 및 원자재

원자재

준비 용품


2-Fluoro-N-Methyl-5-nitroaniline 공급 업체

글로벌( 38)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Sense Chemicals (Shanghai) Co., Ltd.
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Accela ChemBio Inc.
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Fuxin Pharmaceutical
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Hefei TNJ Chemical Industry Co.,Ltd.
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Aromsyn Co., Ltd.
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Aceschem Inc.
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Nanjing New Thinking Chem Co.,Ltd
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Aladdin Scientific
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