2-Amino-5-nitrophenol is used in hair dyes and as an intermediate
in preparing azo dyes.
일반 설명
Brown amorphous granules or powder. Melting point 198-202°C.
공기와 물의 반응
Is slowly oxidized by air at room temperature. Insoluble in water.
반응 프로필
2-Amino-5-nitrophenol is a reducing agent. Incompatible with strong oxidizing agents. Reacts slowly with oxygen in the air at room temperature. Stable at temperatures up to 140°F for two weeks when kept in the dark and under nitrogen. Stable under nitrogen for up to 24 weeks 77°F. Incompatible with strong bases . Incompatible with acid chlorides and acid anhydrides.
화재위험
Flash point data for 2-Amino-5-nitrophenol are not available. 2-Amino-5-nitrophenol is probably combustible.
Carcinogenicity
The potential carcinogenicity of 2-amino-5-nitrophenol
was tested by NTP by oral administration (gavage) in
corn oil to F344/N rats (100 and 200 mg/kg) and B6C3F1
mice (400 and 800 mg/kg) for 2 years. There was some
evidence of carcinogenic activity in low-dose male rats, as
indicated by increased incidence of acinar cell adenomas of
the pancreas. No evidence of carcinogenic activity was found
among female rats and the low-dose groups of male and
female mice. The poor survival rates in the high-dose male
rats and high-dose male and female mice reduced the sensitivity
for detecting potential carcinogenic response.
Purification Methods
Crystallise the phenol from water. [Beilstein 13 IV 803.]
