4-Hydroxyphenylboronic acid
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4-Hydroxyphenylboronic acid 속성
- 녹는점
- >230 °C (lit.)
- 끓는 점
- 351.4±44.0 °C(Predicted)
- 밀도
- 1.32±0.1 g/cm3(Predicted)
- 저장 조건
- Inert atmosphere,Room Temperature
- 용해도
- soluble in Acetonitrile, DMSO, Methanol
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 9.09±0.10(Predicted)
- 색상
- 황백색부터 연한 갈색까지
- 수용성
- 25g/L
- BRN
- 2963491
- InChIKey
- COIQUVGFTILYGA-UHFFFAOYSA-N
- CAS 데이터베이스
- 71597-85-8(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi,C | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 36/37/38-34 | ||
| 안전지침서 | 26-36-37/39-45-36/37/39-27 | ||
| WGK 독일 | 3 | ||
| TSCA | No | ||
| HS 번호 | 2931 90 00 | ||
| 위험 등급 | IRRITANT |
4-Hydroxyphenylboronic acid C화학적 특성, 용도, 생산
화학적 성질
off-white to light brown powder용도
4-Hydroxyphenylboronic acid can be used as a reactant in:- Suzuki-Miyaura coupling and Stille coupling reactions.
- Palladium-catalyzed aminocarbonylation and cross-coupling reactions.
- Suzuki reaction for preparation of bio-supported palladium nanoparticles as phosphine-free catalysts.
- Cu2O-catalyzed aerobic oxidative cross-coupling of tetrazoles.
It can also be used to prepare/promote:
- PDK1 inhibitory activity (cancer cell growth, survival, and tumorigenesis inhibitor).
- Rod-like dendronized polymers containing G4 and G5 ester dendrons via macromonomer approach by living ROMP.
- Estrone-derived cyclopamine analogs as Sonic Hedgehog signaling inhibitors for anti-cancer chemotherapeutics.
- Enzymatic inhibitors for the treatment of Gram-negative bacterial infections.
- Oligoarenes by Suzuki-Miyaura palladium-catalyzed cross-coupling.
Synthesis Reference(s)
Tetrahedron Letters, 37, p. 6705, 1996 DOI: 10.1016/S0040-4039(96)01468-24-Hydroxyphenylboronic acid 준비 용품 및 원자재
원자재
테트라하이드로푸란
4-브로모페놀
보릭산트리이소프로필에스테르
부틸리튬
Boronic acid, B-[4-[[(4-methylphenyl)sulfonyl]oxy]phenyl]-
4-Ethoxyphenylboronic acid
4-Benzyloxybenzeneboronic acid
1,4-Phenylenebisboronic acid
(4-BROMOPHENOXY)TRIMETHYLSILANE
4-ACETOXYPHENYLBORONIC ACID
(4-BROMOPHENOXY)-TERT-BUTYLDIMETHYLSILANE
준비 용품
4-Hydroxyphenylboronic acid 공급 업체
글로벌( 418)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hebei Xinsheng New Material Technology Co., LTD. | +86-16632316109 |
xinshengkeji@xsmaterial.com | China | 1100 | 58 |
| Anhui Ruihan Technology Co., Ltd | +8617756083858 |
daisy@anhuiruihan.com | China | 994 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 18229 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 15957 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21689 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 |
product@chemlin.com.cn | CHINA | 3012 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32686 | 60 |
| Beijing Green Guardee Technology Co., Ltd | 86-010-69706062 |
sales2@greenguardee.com | CHINA | 650 | 58 |
| Zjartschem | +86-571-8723 8903 jocelynpan@zjarts.com |
jocelynpan@zjarts.com | CHINA | 993 | 58 |