눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
4 4'-DIISOTHIOCYANATO-2 2'-STILBENEDISU& C화학적 특성, 용도, 생산
용도
4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid disodium salt hydrate has been used:
as band3 protein inhibitor in rabbits(19)
for the inhibition of bicarbonate transporters in brain slice tissue(20)
as HCO3-/Cl- exchanger (anion exchanger) in embryos(21)
Biochem/physiol Actions
4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid is an anionic alkylating agent containing isothiocyanate residue. It is a negatively charged homobifunctional cross-linking reagent. 4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid is a specific inhibitor of cellular anion permeability used in cell transport studies. The isothiocyanate groups react with primary amines at pH 9.0-10.0. 4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid alkylates lysine residues and inhibits apoptosis indirectly by targeting membrane based anion transporters.In addition, it also inhibits calcium transport in vesicles.
4 4'-DIISOTHIOCYANATO-2 2'-STILBENEDISU& 준비 용품 및 원자재
