Dynorphin A (1-13)

Dynorphin A (1-13) 구조식 이미지
카스 번호:
72957-38-1
상품명:
Dynorphin A (1-13)
동의어(영문):
Dyn(1-13);YGGFLRRIRPKLK;DYNORPHIN 1-13;DYNORPHIN A (1-13);sh-Oligopeptide-71;Dynorphin A1-13【pig】;Dynorphin A(1-13)【pig】;Dynorphin A(1-13)【rat】;DYNORPHIN A(HUMAN, 1-13);Dynphin A (1-13) Acetate
CBNumber:
CB6699152
분자식:
C75H126N24O15
포뮬러 무게:
1603.95
MOL 파일:
72957-38-1.mol

Dynorphin A (1-13) 속성

밀도
1.39±0.1 g/cm3(Predicted)
RTECS 번호
JV7436666
저장 조건
Inert atmosphere,Store in freezer, under -20°C
물리적 상태
고체
물리적 상태
단단한 모양
산도 계수 (pKa)
3.31±0.10(Predicted)
수용성
Water: ≥ 60 mg/mL (37.41 mM)
시퀀스
H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-OH
InChIKey
OVVIBUHLQIYUEU-JASZZEBFNA-N

안전

WGK 독일 3
HS 번호 2933998090

Dynorphin A (1-13) C화학적 특성, 용도, 생산

개요

Dynorphin A(1-13), a tridecapeptide of the endogenous opioid peptides, has modest effects in reducing mild opiate withdrawal in humans. Previous studies revealed that dynorphin also potentiates the analgesic effect of morphine in morphine-tolerant rats and mice. The therapeutic potential of dynorphin A(1-13) is limited due to extensive metabolism by human metabolic enzymes resulting in an in vivo half-life of less than one minute. Chemical modifications of dynorphin A(1-13), such as N-methylation of Tyr1 and amidation of the C-terminus have been shown to be effective in protecting against the proteolytic enzymes in human plasma[1].

Dynorphin A (1-13) 준비 용품 및 원자재

원자재

준비 용품


Dynorphin A (1-13) 공급 업체

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